Lord Kerslake resigns as King’s College Hospital Trust chair

The House of Lord peer says the government is unrealistic about the challenges facing the NHS.

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Health24.com | A digital pill can tell if you’re taking your meds

Many doctors feel frustrated by patients who don’t follow their instructions and take their medications as prescribed.

But now, pairing medication with an ingestible sensor can help clinicians track how often and when patients actually take their prescription drugs, according to a small new investigational study.

A special configuration

The findings come on the heels of the US Food and Drug Administration’s decision last month to approve the first digital pill for use with the antipsychotic drug Abilify, often prescribed to treat schizophrenia, bipolar disorder and depression.

The new research involved just 15 patients, all of whom had been prescribed the opioid pain drug oxycodone (OxyContin) after sustaining a fracture.

The findings were published in the journal Anesthesia & Analgesia.

The study participants were given a special configuration of oxycodone. The pain med was packaged together with a so-called “digital pill”. This meant that each time a patient took the pain med, they ingested a gelatine capsule that contained the oxycodone as well as a radiofrequency emitter.

The emitter was automatically activated when the capsule was swallowed. It sent signals to a sticky patch placed on the person’s abdomen. That, in turn, conveyed basic pill-taking information to an iPod-sized reader.

Changes in medication-taking behaviour

There are however fears that this kind of system could be regarded as a “biomedical Big Brother” and if used improperly, could foster mistrust.

The system enabled researchers to track how many pills the 15 patients actually took, rather than the number of pills they’d been given.

On average, the patients took just six pills in total – even though they had been provided a supply of 21 pills, according to the report.

“As an investigational tool, the digital pill provides a direct measure of opioid ingestion and changes in medication-taking behaviour,” senior author Dr Edward Boyer said in a news release from Brigham and Women’s Hospital in Boston.

“This technology may also make it possible for physicians to monitor adherence, identify escalating opioid use patterns that may suggest the development of tolerance or addiction, and intervene for a specific medical condition or patient population,” he added.

Boyer is with the medical toxicology division within the hospital’s department of emergency medicine.

Image credit: iStock

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Health24.com | 5 signs you could be at risk for deep vein thrombosis

Deep vein thrombosis (or DVT) is when a blood clot forms in a vein deep in your body, usually in the legs. Symptoms can range from nothing to swelling, pain, cramping, soreness, discoloration or even a feeling of warmth in your leg(s).

But the real trouble starts if one of these clots breaks free and moves to your lungs, says Anthony Carcella, a mountain biker and physician assistant in emergency medicine.

“Having DVT in your leg is usually not a big deal,” Carcella says. “But if it gets to your lungs it can block blood flow, which is really dangerous and possibly fatal.”

So what are the risk factors, and what can you do to diminish them?

1. You’ve inherited some risk

Carcella says some people simply inherit a disorder that makes their blood clot more easily (Factor V Leiden, for instance). But this condition all by itself is not a guarantee of problems. It does, however, increase the likelihood of issues when combined with other risk factors, such as age.

Blood clots can happen at any time in life but are more common after the age of 40; that risk jumps even higher after 60. Add obesity to this equation, and you up the ante even further.

So while you can’t turn back time or change your genetics, you can watch your weight.

2. You sit too much

Whether it’s because they’re sitting for multiple hours on a transatlantic flight or confined to a hospital bed post-surgery, even healthy, active people experience increased DVT risk when they don’t move around for prolonged periods of time.

This is because your calf muscles contract when you walk around, which helps keep blood flowing.

If you’re on a long-haul flight, Carcella recommends getting up and moving around every 30 to 60 minutes.

And even when sitting, you can flex your foot back and forth, which helps contract your calf.

Compression socks can also be helpful because they apply gentle pressure to the calf, ankle and foot, lessening swelling and promoting proper circulation.

3. Your hormones are in flux

It’s a double whammy for women here. When pregnant, the increased pressure on your pelvis and legs also affects your veins, ramping up the chance of DVT. This is especially true if you also have a family history of clotting issues.

Oral contraceptive birth control and hormone replacement therapy have also been linked to DVT, as the oestrogen in these medications can raise your blood’s ability to clot.

4. You’re obese – or a smoker

Having a BMI (or body mass index) over 30 increases your chances for DVT. This measure indicates how much body fat you have compared to your height and weight.

Fortunately, this isn’t an issue for many if not most cyclists, who keep the weight down by cranking out kays on their bike. Most don’t smoke either, which is another DVT risk factor.

Smoking makes your blood stickier than normal and also harms the blood vessel lining, increasing the chance for clot formation.

5. You’ve had cancer, heart problems or surgery

Having surgery, cancer, heart failure or even an irregular heartbeat can all contribute to a greater risk of deep vein thrombosis.

Surgery, especially when below the waist, ups the ante both because it often leaves you temporarily immobile, and also because of the inherent damage done to blood vessels during the procedure.

Cancer patients, meanwhile, have seen a greater DVT occurrence, which has been linked to chemotherapy treatment.

In cases of heart failure, your body’s ability to pump blood is reduced, which increases the chance and impact of DVT.

And people with an irregular heartbeat are more susceptible to blood not being thoroughly pumped through your heart’s ventricles.

This article was originally published on www.bicycling.co.za

Image credit: iStock

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Teachers call for ban on energy drinks in schools

A teaching union compares energy drinks to “legal highs” and says pupils are consuming them in “excessive quantities.”

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