Led by Jie V. Zhao, Yitang Sun, Junmeng Zhang, and Kaixiong Ye from the University of Hong Kong and the University of Georgia, the research team focused on phenylalanine and tyrosine. Their findings suggest that higher tyrosine levels are associated with shorter life expectancy in men, raising the possibility that longevity strategies may need to differ by sex.

Amino Acids, Brain Function, and Aging

Phenylalanine and tyrosine are amino acids that play important roles in metabolism and brain activity. They are naturally present in protein rich foods and are also sold as dietary supplements. Despite their widespread use, scientists still do not fully understand how these compounds may affect the aging process over time.

Tyrosine is especially notable because it helps produce neurotransmitters such as dopamine, which influence mood, motivation, and cognitive performance. Because of its role in brain chemistry, tyrosine has drawn increasing interest in aging research.

Large UK Biobank Study Examines Lifespan

To investigate potential links to longevity, the researchers analyzed health and genetic data from more than 270,000 participants in the UK Biobank. They used both observational data and genetic techniques to assess whether blood levels of phenylalanine and tyrosine were related to overall mortality and predicted lifespan.

At first, both amino acids appeared to be associated with a higher risk of death. However, after deeper analysis, only tyrosine showed a consistent and potentially causal relationship with reduced life expectancy in men. Genetic modeling suggested that men with elevated tyrosine levels could live nearly one year less on average. No meaningful association was found in women.

The connection remained even after accounting for other related factors, including phenylalanine. This strengthens the possibility that tyrosine itself may independently influence aging. Researchers also noted that men generally have higher tyrosine levels than women, which may help explain part of the longstanding lifespan gap between the sexes.

“Phenylalanine showed no association with lifespan in either men or women after controlling for tyrosine.”

Possible Biological Explanations

Scientists are still working to understand why tyrosine might affect lifespan in men. One possibility involves insulin resistance, a condition linked to many age related diseases. Tyrosine is also involved in producing stress related neurotransmitters, which may influence metabolic and hormonal pathways differently in men and women. Variations in hormone signaling could help explain why the effect appeared only in men.

Supplement Use and Longevity Questions

Tyrosine is often marketed as a supplement to improve focus and mental performance. Although this study did not directly test tyrosine supplements, the findings raise questions about its long term impact on health and lifespan.

The researchers suggest that individuals with high tyrosine levels might benefit from dietary adjustments. Approaches such as moderating overall protein intake could potentially lower tyrosine levels and support healthier aging.

More research will be needed to confirm these results and to determine whether changes in diet or lifestyle can safely reduce tyrosine levels and promote longer life.

New research led by the University of Colorado Boulder and published in Nature Geoscience explains what happened in 2023, when the glacier lost about eight kilometers of ice in just 60 days. The study found that the key factor was the flat bedrock beneath the glacier. As the ice thinned, this smooth foundation allowed large sections to lift off the ground and float, triggering an unusual and sudden calving event.

The findings could help scientists pinpoint other Antarctic glaciers that might be vulnerable to similar rapid collapse. Hektoria Glacier is relatively small by Antarctic standards, covering about 115 square miles, roughly the size of Philadelphia. However, if a much larger glacier were to retreat this quickly, the consequences for global sea level rise could be severe.

“When we flew over Hektoria in early 2024, I couldn’t believe the vastness of the area that had collapsed,” said Naomi Ochwat, lead author and CIRES postdoctoral researcher. “I had seen the fjord and notable mountain features in the satellite images, but being there in person filled me with astonishment at what had happened.”

Satellite Data Revealed a Sudden Collapse

Ochwat and her colleagues, including CIRES Senior Research Scientist Ted Scambos, were initially studying the region for a different project. They were investigating why sea ice detached from a glacier years after a nearby ice shelf broke apart in 2002.

While reviewing satellite and remote sensing data, Ochwat noticed something unexpected. The images showed that Hektoria Glacier had retreated dramatically within a short window of time. That discovery led her to focus on a pressing question: why did this glacier collapse so quickly?

Ice Plain Topography and Grounding Lines

Many Antarctic glaciers are tidewater glaciers, meaning they sit on the ocean floor and extend into the sea, where they release icebergs. The landscape beneath them can vary widely. Some rest over deep troughs or underwater mountains, while others lie across broad, flat plains.

Hektoria sat on what scientists call an ice plain, a flat stretch of bedrock below sea level. Geological evidence shows that between 15,000-19,000 years ago, glaciers positioned over similar ice plains retreated at extraordinary speeds, sometimes moving back hundreds of meters per day. That historical insight helped researchers interpret what they were seeing at Hektoria.

When a tidewater glacier thins enough, it can lift off the seabed and begin floating on the ocean surface. The location where it transitions from grounded to floating ice is known as the grounding line. By analyzing multiple satellite datasets, the team identified several grounding lines at Hektoria, a sign of ice plain conditions beneath the glacier.

Rare Calving Process Triggered Rapid Ice Loss

Because the glacier rested on a flat bed, large portions were able to lift off almost at once. Once afloat, the ice was exposed to powerful ocean forces. Cracks opened along the base of the glacier and eventually connected with fractures at the surface. This chain reaction caused extensive calving, breaking apart nearly half the glacier in a matter of weeks.

By combining frequent satellite observations, the researchers reconstructed the sequence of events in detail.

“If we only had one image every three months, we might not be able to tell you that the glacier lost two and a half kilometers in two days,” Ochwat said. “Combining these different satellites, we can fill in time gaps and confirm how quickly the glacier lost ice.”

Glacier Earthquakes Confirmed Ice Loss

The team also deployed seismic instruments that detected a series of glacier earthquakes during the period of rapid retreat. These tremors confirmed that the glacier had been firmly grounded on bedrock before lifting off. The data not only verified the presence of an ice plain but also showed that the ice loss directly contributed to rising global sea levels.

Ice plains have been identified beneath many other Antarctic glaciers. Understanding how they influence retreat rates will help scientists better forecast which glaciers might be prone to sudden collapse in the future.

“Hektoria’s retreat is a bit of a shock — this kind of lighting-fast retreat really changes what’s possible for other, larger glaciers on the continent,” Scambos said. “If the same conditions set up in some of the other areas, it could greatly speed up sea level rise from the continent.”

Their findings appear in a review published in Nature Photonics, which examines the rapid advances in creating, controlling, and measuring structured quantum light. The paper highlights a growing set of powerful tools, including on-chip integrated photonics, nonlinear optics, and multiplane light conversion. Together, these methods are transforming structured quantum states from laboratory concepts into practical systems for imaging, sensing, and quantum networks.

From Empty Toolbox to Advanced Quantum Control

Professor Andrew Forbes of Wits University, the study’s corresponding author, says the transformation in this field over the past 20 years has been remarkable. “The tailoring of quantum states, where quantum light is engineered for a particular purpose, has gathered pace of late, finally starting to show its full potential. Twenty years ago the toolkit for this was virtually empty. Today we have on-chip sources of quantum structured light that are compact and efficient, able to create and control quantum states.”

A major advantage of shaping photons is that it allows researchers to use high-dimensional encoding alphabets. In simple terms, each photon can carry more information and resist interference more effectively. That makes structured quantum light especially attractive for secure quantum communication systems.

Challenges in Long-Distance Quantum Communication

Despite the progress, real-world conditions still pose obstacles. Certain communication channels are not well suited for spatially structured photons, which limits how far these signals can travel compared to more traditional properties such as polarisation. “Although we have made amazing progress, there are still challenging issues,” says Forbes. “The distance reach with structured light, both classical and quantum, remains very low … but this is also an opportunity, stimulating the search for more abstract degrees of freedom to exploit.”

To address this limitation, researchers are exploring ways to give quantum states topological properties. Topological features can make quantum information more stable against disturbances. “We have recently shown how quantum wave functions naturally have the potential to be topological, and this promises the preservation of quantum information even if the entanglement is fragile,” says Forbes.

Multidimensional Entanglement and Future Applications

The review also outlines fast-moving developments in multidimensional entanglement, ultrafast temporal structuring, advanced nonlinear detection techniques, and compact on-chip devices that can generate or process higher-dimensional quantum light than ever before. These breakthroughs are paving the way for high-resolution quantum imaging, extremely precise measurement tools, and quantum networks capable of transmitting more data through multiple interconnected channels.

Overall, the field appears to be reaching a pivotal moment. Researchers believe quantum optics based on structured light is poised for major growth, with the future looking “very bright indeed” — but additional work is required to increase dimensionality, raise photon output, and design quantum states that can withstand realistic optical environments.