There May Be A New Way To Clear Alzheimer’s Proteins From The Brain

For a long time, the development of dementia has been associated with the buildup of proteins like amyloid plaques and tau.

Amyloid plaques are sticky bundles of abnormal protein fragments, while tau tangles are made up of stringy proteins. Combined, this pair has been compared to the “trigger and bullet” in dementia formation.

But scientists might have just made a step forward in dealing with them.

Presenting her team’s findings at the Alzheimer’s Association International Conference in London last week, neuropsychologist Dr Sephira Ryman, who led a team of researchers from The University of New Mexico School of Medicine and the Mind Research Network (MRN), said that carbon dioxide can help to “pump” out tau before it can accumulate.

This follows earlier Parkinson’s research

In 2025, Dr Ryman and her team published a paper which suggested that exposing the brain to low-level bursts of CO2 could help to “clear potentially toxic brain byproducts”.

It did this, they said, by activating our body’s glymphatic system. The glymphatic system removes waste from our brain (especially as we sleep) and seems to be impaired in people with conditions like Parkinson’s.

This initial paper found that three 10-minute sessions of inhaling higher-than-usual amounts of CO2 seemed to help Parkinson’s patients’ brains clear unwanted buildup – in this case, alpha-synuclein.

At the time, Dr Ryman said: “we realised that we could reproduce, in the awake state, the glymphatic clearing response usually linked to deep sleep using intermittent CO2”.

Since then, the group have conducted a study on 12 people – eight of which had normal tau levels, and four of which had more tau buildup, New Scientist shared. Three of the four people had mild cognitive impairment, sometimes seen as a precursor to dementia.

The researchers scanned participants’ brains as they wore masks which released bursts of higher-CO2 air, switching from normal levels of the gas to 10 times the usual amount every 35 seconds for half an hour.

This seemed to activate their glymphatic system, and after the procedure was done, tau clearance appeared to be improved among those with high levels of it.

And all participants’ blood had higher levels of beta-amyloid (which can lead to the amyloid plaques we mentioned earlier) after the session too.

“This suggests this neurodegenerative marker was being cleared more out of the brain,” Dr Ryman said.

Researchers wonder whether this means breathing techniques might be good for our brains

In a paper for the Journal of Cerebral Blood Flow and Metabolism, Dr Ryman and her colleagues said: “Breath-centered practices such as yoga, tai chi, and qigong have been utilised for centuries to manage stress and promote psychological well-being.

“Emerging research reveals an additional benefit: these practices also stimulate cerebrospinal fluid oscillations, potentially activating the glymphatic pathway during wakefulness.”

However, more research is needed to confirm their findings.

It’s also worth noting that the amyloid and tau-clearing power of the treatment seemed to stop an hour later (though the glymphatic system doesn’t work 24/7, either).

Additionally, some experts say we’re not yet sure whether clearing processes like these will definitely help to prevent or slow cognitive decline, even if they succeed.

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Madonna’s Rep Denies Rumours Singer Was Spotted In Donald Trump’s World Cup Suite

Madonna has hit back at the suggestion that she spent a portion of the World Cup final in the same suite as US president Donald Trump.

On Sunday night, the Queen of Pop was one of the headliners at Fifa’s first ever World Cup halftime show, performing a mash-up of her classic song Music and recent hit Danceteria alongside some iconic football cameos.

After the final, footage began doing the rounds on social media which some suggested showed Madonna hanging out in the same suite as the US leader and First Lady (one such post has racked up almost 24 million views at the time of writing, in the two days since it was first shared).

However, a rep for the Like A Prayer singer has since clarified to Rolling Stone that it is not her in the video, and that she was not ever in Trump’s suite at the World Cup.

Donald Trump on Sunday night at the World Cup final
Donald Trump on Sunday night at the World Cup final

via Associated Press

Since Trump’s political career began in the 2010s, Madonna has been among his vocal detractors.

At the Women’s March ahead of his 2017 inauguration, the Grammy winner raised eyebrows when she delivered a speech claiming that she’d thought “an awful lot about blowing up the White House” since his election.

This prompted a response from Trump himself at the time, who branded Madonna “disgusting” and claimed that her remarks were “disgraceful to our country”.

Following the controversy that ensued, she later clarified that her comment had been taken “wildly out of context”, insisting: “I am not a violent person, I do not promote violence and it’s important people hear and understand my speech in its entirety rather than one phrase.”

After Trump’s victory in the most recent US election was declared, Madonna made headlines when she posted a picture of a cake emblazoned with the message “fuck Trump” on Instagram, fuming at the time that she was “trying to get my head around why a convicted felon, rapist, bigot was chosen to lead our country because he’s good for the economy”.

Last year, Madonna continued to make a string of comments against Trump, accusing his administration ofslowly dismantling all the freedoms we have been fighting for and WON over the years”, referring specifically to LGBTQ+ rights.

“Don’t give up the fight!” she urged her followers.

The chart-topping musician later lamented that “fascism” had “become banal and the norm”, and months afterwards, criticised him again in an impassioned post to commemorate World AIDS Day.

Madonna – a vocal advocate for HIV and AIDS awareness throughout her career – wrote on social media: “Donald Trump has announced that World AIDS Day should no longer be acknowledged.

“It’s one thing to order federal agents to refrain from commemorating this day, but to ask the general public to pretend it never happened is ridiculous, it’s absurd, it’s unthinkable.

She added: “I bet he’s never watched his best friend die of AIDS, held their hand, and watched the blood drain from their face as they took their last breath at the age of 23.”

Madonna’s criticism of Trump, in fact, stretches back a lot further than his presidency, as she was branding him a “wimp” in the press as far back as 1990.

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Martin Lewis Weighs In On How Andy Burnham Should Handle The Cost Of Living

New prime minister Andy Burnham has announced that the government will cut VAT (value added tax) from electricity bills as part of his campaign to lower the cost of living. Some think he may cap bus fares at £2, too.

His government’s new chancellor, John Healey, who replaced Rachel Reeves on Monday, said: “For too long, too many people have struggled with the cost of living. Today’s energy tax cut will give families some breathing room on bills, and provide some reassurance this winter.”

On X, Money Saving Expert’s founder and executive chair, Martin Lewis, has spoken about how he thinks the new PM should tackle the cost of living.

“For me, there are three main areas,” he shared in a video.

These are:

1) The cost of living

This is “pretty obvious”, the money guru said. He claimed: “We’ve had high inflation for a long time, and though inflation has come down now, that just means prices aren’t rising as quickly as they were”.

In other words, though price hikes have slowed, we may still be paying more than previous years due to former periods of high inflation. Costs aren’t rocketing up as fast, but they’re not lowering either.

“So, things feel expensive,” Lewis continued, adding that cutting VAT from electricity bills is a “totem of help”.

However, he said: “It’s only a small amount… there needs to be more policy costs coming off energy bills. We need to look at banning mid-contract price hikes on mobile and broadband [services].”

Lewis also addressed water bill hikes, which have risen by 40% in some areas, and high mortgages and rents.

2) Intergenerational problems

“What I mean by this is basically, young people being shafted,” the expert said. “The job market is tough, AI is going to make that even more difficult.”

Job vacancies fell to half their 2022 levels in the three months leading to May 2026.

Lewis also stated that “the current government is making it worse for the millions of people with outstanding Plan 2 student loans… it’s going to freeze the repayment threshold from April”.

When Plan 2 student loans were announced, the government said the £21,000 earnings threshold would be updated every year in line with earnings from 2016 (in other words, it’d take a higher wage until the government asked you to pay your loan back).

But this was frozen from 2016 to 2018, and again from 2021 to 2025, and in last year’s budget, it was announced it would be frozen again for three years.

“If you freeze this repayment [and] people’s earnings are going up, then they’re paying more back,” Lewis said, claiming: “It is a breach of the original promise”.

He said he hopes the new government overturns the freeze as one of its first acts.

Calling the entire student loan system “broken”, Lewis continued: “the level of interest needs to be cut, repayment [thresholds] need to be higher”.

The money pro pointed out that the amount of money that qualifies someone for a maintenance grant has stayed the same since 2008, even though costs have gone up.

3) The ‘helped and helped-nots’

Lewis called discussions around “who do you help and who don’t you help when it comes to the cost of living” the “biggest of all the challenges”.

He said that some of the “visceral anger” he perceived towards former PM Keir Starmer comes from people who feel they’ve been “left out of help”.

“They are just above getting benefits, just above qualifying for social tariffs, just above qualifying for pension credit,” he said. “They’re on low to low-middle incomes, and they haven’t got any help.”

Lewis said that Burnham faces a “real challenge” in deciding “exactly where to draw the line” on support.

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Astronomers find the first atmosphere on a rocky world in the habitable zone

Astronomers have reached a major turning point in the search for life beyond Earth by detecting an atmosphere around a rocky, Earth-like planet located in another star’s habitable zone.

The discovery offers the strongest evidence so far that planets with broadly Earth-like temperatures and rocky compositions may exist beyond our solar system while also retaining conditions that could potentially support life.

“An atmosphere is essential for a planet to support life as we know it,” said lead author Collin Cherubim, who recently earned his Ph.D. in Earth and Planetary Sciences from Harvard University.

“This is the first time anyone has found an atmosphere on a rocky planet in the habitable zone of another star.”

Helium Reveals an Exoplanet Atmosphere

The study, published July 16 in Science, describes observations of helium escaping from LHS 1140 b, a rocky exoplanet located about 48 light-years from Earth. The signal supports earlier theoretical predictions that the planet possesses an atmosphere.

LHS 1140 b circles a red dwarf star within its habitable zone. This is the region around a star where temperatures and other environmental conditions may allow liquid water to remain on a planet’s surface.

Scientists have identified thousands of exoplanets, including several rocky worlds in habitable zones. However, confirming whether those planets have atmospheres has been one of the most difficult challenges in exoplanet research.

“Twenty years ago we wondered whether other terrestrial-type planets even existed,” said Robin Wordsworth, Gordon McKay Professor of Environmental Science and Engineering and Professor of Earth and Planetary Sciences at Harvard and one of Cherubim’s dissertation advisors. “Then we learned they’re common, and found some in the habitable zone. The next question was whether any of them had managed to keep an atmosphere. Now we know at least one has.”

A Rocky World That Kept Its Atmosphere

Previous research has identified rocky planets orbiting within the habitable zones of their stars. This study, however, is the first to clearly show that one of those worlds has an atmosphere that may have endured for billions of years.

Cherubim and his colleagues developed a theoretical model predicting that the upper atmosphere of LHS 1140 b would contain large amounts of helium slowly escaping into space.

The researchers tested that prediction using the Warm Infrared Echelle (WINERED) Spectrograph at the Magellan Observatory in Chile. Their observations took advantage of an unusual event in which LHS 1140 b and another planet crossed in front of their star during the same night.

The second planet showed no sign of an atmosphere. LHS 1140 b, however, produced a clear signal of helium escaping from the planet, providing evidence that it still retains an atmosphere.

A Prediction Confirmed by Telescope Data

Cherubim’s joint advisor David Charbonneau, head of the Harvard Department of Astronomy and astronomer in the Center for Astrophysics | Harvard & Smithsonian, initially doubted whether the plan would succeed. The prediction came from a mathematical model, and this type of signal had never before been observed from a rocky world.

The results changed his mind.

“Collin analyzed the planets we knew about and predicted that this one would have a helium atmosphere,” Charbonneau said. “Then he organized telescope time, got the data, and the detection was statistically rock solid.”

The discovery indicates that astronomers may be able to study the atmospheres of rocky exoplanets from the ground by looking for gases escaping into space.

A Promising Target in the Search for Life

Astronomers estimate that the atmosphere of LHS 1140 b has survived for more than three billion years. That longevity makes the planet an especially promising target for additional observations.

Cherubim hopes to identify the atmosphere’s complete chemical composition and eventually determine whether the planet has surface oceans or other features connected with habitability. He and his colleagues also plan to use the model to search for additional rocky worlds with atmospheres.

“This has been a model validation, and hopefully it’s just the first of many more observations to come,” he said.

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Ancient DNA reveals a chilling secret at China’s 4,000-year-old Shimao city

Ancient DNA is revealing new details about the people who lived at Shimao, one of the most important late Neolithic settlements in China. The findings, published in Nature, clarify the population’s origins, family relationships, and social organization. They also identify genetic connections with communities farther south and provide evidence that mass burials linked to human sacrifice at the site largely contained men.

The project was led by Prof. Qiaomei Fu of the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) at the Chinese Academy of Sciences. Researchers from the Shaanxi Provincial Academy of Archaeology and several other institutions also contributed to the work.

Over 13 years, the team conducted large-scale, high-resolution analyses of nuclear DNA from 169 ancient human samples (144 unrelated individuals). The remains came from Shimao, nearby archaeological sites, and locations in the southern Shanxi region.

A Vast Walled Settlement in Ancient China

Shimao dates to approximately 4200-3700 years before the present and is located in northern Shaanxi Province, China. Covering about four square kilometers, the enormous stone-walled settlement was divided into separate functional areas.

Archaeological evidence indicates that Shimao had a strongly stratified society with organized political and social systems. The site has also produced extensive evidence of ritual activity and human sacrifice.

Local Roots and Distant Connections

Researchers compared the newly obtained genomes with previously published ancient DNA from populations across China. Their results indicate that most of Shimao’s inhabitants descended from local people who had lived in the region about 1,000 years earlier.

The analysis also uncovered both genetic and cultural links to Yangshao Culture, a major Neolithic civilization that developed across the Loess Plateau near the Yellow River. These connections provide important clues about where the Shimao population came from and how its society developed.

The Shimao people were also closely connected to communities associated with Taosi Culture (southern Shanxi), steppe Yumin-related groups, and southern rice-farming populations. These relationships point to extensive contact and exchange among prehistoric farming and pastoral communities across a wide geographic area.

Ancient DNA Reconstructs Shimao Families

Around 80 human skulls have been discovered near Shimao’s East Gate. Before the late Shang period, no other archaeological site in China had produced such a large collection of human skulls.

Genetic analysis allowed the researchers to reconstruct family pedigrees covering as many as four generations. The results suggest that Shimao’s social hierarchy was organized through patrilineal descent, meaning ancestry and status were traced through fathers. The population also followed patrilocal residence, in which women typically moved to live with or near the families of their male partners.

Together, these patterns offer a rare view of how family relationships may have shaped authority, inheritance, and social rank within the settlement.

Male Sacrifice at Shimao’s East Gate

The findings also overturn a long-held idea about the people sacrificed near Shimao’s East Gate. Earlier interpretations suggested that most of the victims were female, but the genetic evidence shows that nine out of ten burials examined there were male.

A clear pattern emerged across different areas of the settlement. Male sacrificial victims were concentrated near the East Gate, while female sacrificial remains were found in elite cemeteries including Huangchengtai and Hanjiagedan.

This separation suggests that sacrifice at Shimao was carefully organized. Men and women may have been selected for different ceremonies, with their roles determined by the purpose of the ritual and the location where it took place.

New Clues to the Rise of Early States

The genetic evidence indicates that Shimao’s population primarily developed from local groups with Yangshao cultural ancestry in northern Shaanxi. This establishes at least 1,000 years of cultural and genetic continuity in the region.

At the same time, the population’s links to distant communities show that Shimao was not isolated. Its people participated in broad networks connecting agricultural and pastoral societies across northern, central, and southern China.

The study also provides the first direct genetic evidence that can be used to investigate how power was inherited at Shimao, who belonged to its ruling families, and how different social classes were formed. These insights may help researchers better understand the family systems and political structures that contributed to the emergence of early states in East Asia.

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Scientists found mystery bacteria inside one of the ocean’s most elusive whales

Pygmy sperm whales (Kogia breviceps) are some of the least understood mammals in the ocean. They spend most of their lives far from shore, usually traveling in small groups and diving deep to hunt squid and fish. Because they are quiet, secretive, and rarely seen at the surface, scientists have had few opportunities to observe them in the wild.

Much of what researchers know about pygmy sperm whales has come from animals that wash ashore. Strandings are especially common along the southeastern United States, where this species appears more frequently than almost any other large marine mammal.

Whale Strandings Reveal Hidden Health Problems

Examinations of stranded whales have uncovered several recurring medical problems, including stomach ulcers. These ulcers are sometimes associated with Helicobacter, a group of bacteria that can live in the stomach and intestines of many animals, including humans and whales.

After reviewing more than 20 years of stranding records and preserved tissue samples, researchers at Florida Atlantic University’s Harbor Branch Oceanographic Institute and collaborating institutions identified three Helicobacter genotypes that had never been documented before.

The study, published in the Journal of Wildlife Diseases, marks the first confirmed discovery of these bacterial genotypes in pygmy sperm whales. The researchers named them Kogia Helicobacter 1, 2 and 3. Beyond offering new insight into an elusive whale species, the findings raise broader questions about how bacterial infections may affect marine wildlife and ocean health.

“Helicobacter bacteria have long been associated with gastrointestinal disorders in humans and other animals, including chronic gastritis, ulcers, and even gastric cancer,” said Annie Page, D.V.M., Ph.D., senior author, an associate research professor and clinical veterinarian at FAU Harbor Branch. “To find novel strains of these bacteria in a deep-diving whale species is intriguing.”

Three Bacterial Genotypes New to Science

From 1999 through 2020, FAU Harbor Branch responded to 59 pygmy sperm whale strandings. Post-mortem examinations were completed on 80% of those animals.

In four cases, scientists found spiral-shaped, “spirilliform” bacteria within stomach tissue. The team later reexamined the preserved samples using histopathology, molecular testing and DNA sequencing. That analysis revealed several previously unknown Helicobacter genotypes.

“Two of the genotypes, Kogia Helicobacter 1 and 2, are genetically similar to known Helicobacter species previously found in other cetaceans — such as dolphins and porpoises — and in humans,” said Wendy Marks, corresponding author and a research coordinator of the marine wildlife veterinary medicine and research lab at FAU Harbor Branch. “But Kogia Helicobacter 3 belongs to a more divergent lineage, which emphasizes the possibility that there are far more undiscovered bacteria in the ocean than we realize.”

Researchers found both Kogia Helicobacter 1 and 3 in the forestomach tissue of one whale.

Infected Whales Showed Stomach Damage

Each of the four whales that tested positive also showed clear signs of gastrointestinal disease.

“All four whales that tested positive for Helicobacter had visible gastric pathology,” said Page. “We saw signs of gastritis, gastric ulcers, fibrosis and nematode infestations. In one case, there was also colitis, which suggests that the infection may not be limited to the stomach. While Helicobacter wasn’t listed as the cause of death in any of the whales, these lesions raise questions about its role in gastrointestinal disease.”

The researchers did not conclude that Helicobacter directly caused the whales’ deaths. However, the repeated presence of inflammation, ulcers, tissue scarring and other digestive problems suggests the bacteria could contribute to chronic illness.

Helicobacter was first reported in marine mammals in 2000. Since then, related bacteria have been detected in several cetacean species around the world. In some animals, infection has been connected with low energy, loss of appetite, regurgitation, stomach ulcers and inflammation. Many of these symptoms are similar to those seen in infected humans.

Possible Risks for Vulnerable Whale Populations

“Whales, like humans, appear to be susceptible to certain microbial infections that we’re only beginning to understand,” said Marks. “If chronic Helicobacter infections are causing health issues in these animals, it could have implications not only for individual whale health, but for entire populations — especially for species that are already vulnerable.”

Because pygmy sperm whales are so difficult to study at sea, researchers still do not know how widespread the newly identified bacteria may be or how much they affect the animals over time. Additional testing will be needed to determine whether these infections contribute to illness, strandings or population-level health problems.

The project brought together researchers from FAU Harbor Branch, the University of Florida’s College of Veterinary Medicine, Colorado State University and Marine Mammal Pathology Services.

Decades of Stranding Research Pay Off

“This research underscores the value of long-term marine mammal stranding response programs,” said Page. “Without the ability to study these stranded animals over decades, we never would have discovered these bacteria. Every whale tells a story, and sometimes that story leads us into entirely new scientific territory.”

Study co-authors are Jessy Castellanos-Gell, Ph.D.; Steven Tillis, Ph.D.; James F.X. Wellehan, D.V.M., Ph.D., DACZM; and April Childress, all with the College of Veterinary Medicine, University of Florida; Nicole Pegg, FAU Harbor Branch; David Rotstein, D.V.M., Marine Mammal Pathology Services; Sushan Han, D.V.M., Ph.D., Diagnostic Medicine Center, Colorado State University; and Steve Burton, director, stranding and population assessment, FAU Harbor Branch.

The research was supported by the Florida State Specialty License Plate Program through the “Protect Florida Whales” grant, which is administered by the Harbor Branch Oceanographic Institute Foundation.

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‘If only people knew what a tick could do’ – the deadly meat allergy caused by tick bites

Mammalian meat allergy is a growing problem along Australia’s east coast – and it’s caused by tick bites.

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A Common Tea Could Make Your Workouts More Effective

We’ve written before at HuffPost UK about how good green tea can be for our brain and how its powerful antioxidants could even help to lower dementia risk.

As it turns out, it could prove an excellent way to boost your performance at the gym, as well as aiding in your recovery.

Research suggests that either the drink itself, or a green tea extract, could improve everything from your antioxidant balance during exercise to how well your muscles hold up afterwards.

How can green tea help my workouts?

1) Green tea extract could help your muscles to recover

A 2018 paper found that green tea extract could help to “reduce the marker of muscle damage after exercise”, though it didn’t make participants’ muscles less sore after a gruelling workout.

This “suggests the green tea extract supplementation has positive effects on muscle recovery after strenuous exercise”.

2) Green tea might diminish oxidative stress

Meanwhile, 2021 research suggested that the antioxidants present in green tea (the kind you drink, not a supplement or extract) could help to diminish “oxidative stress” on our bodies while we’re pushing ourselves in the gym.

Oxidative stress is an imbalance of free radicals, which can harm cells, and antioxidants, which neutralise them. This imbalance can sometimes lead to cell damage and can happen during excessive or very heavy exercise.

This research found that “the consumption of green tea during and following exercise can lower oxidative stress,” though the authors added more research is needed. A separate study noted that most people will need to consume green tea regularly for at least a week to see “significant differences” here.

3) Green tea extract could help you last longer during exercise – and may help you burn more fat while doing so

Lastly, green tea extract might help you to burn more fat and push yourself further during workouts, too.

At least, that’s according to a 2025 paper, which focused on the effects of ginger and green tea extracts on active men in different temperatures.

Only green tea extract seemed to consistently improve their cycling endurance and energy efficiency while working out – meaning it relied more on the burning of fat than carbohydrates to power the men’s workouts.

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Rachel Reeves Sacked As Andy Burnham Axes Keir Starmer Loyalists In Brutal Reshuffle

Rachel Reeves has been sacked as chancellor as Andy Burnham axed a raft of Keir Starmer loyalists from cabinet.

In a brutal reshuffle, the new prime minister also dumped David Lammy, Peter Kyle, Steve Reed, Lord Hermer and Liz Kendall.

They are expected to make way for key Burnham supporters, including Louise Haigh.

It is understood that she was offered “a big job” by Burnham but turned it down.

Announcing her departure on X, Reeves said it had been “the privilege of my life to serve as the Chancellor of the Exchequer”.

She said: “The economy today is stronger, fairer and more resilient because of the choices we have taken as a Labour government over the past two years.

“Stability restored, investment delivered and reform to our economy under way. I said when I was appointed chancellor that I would judge my time in office if the lives ordinary working class people have been improved. I’m proud to say that they have.

“And to every young woman and girl let my time in office show there should be no ceilings on your ambitions, your hopes or your dreams.

“I wish the very best of luck to my successor, Andy and his cabinet. You have my full support, and I will continue to play my part in helping this Labour government deliver the change the country needs.”

Lammy, who was Keir Starmer’s deputy PM as well as justice secretary, said he “would have been proud to continue serving” in the cabinet, but had been sacked.

He said: “A new prime minister is entitled to build his own team, and I wish Andy Burnham and the new cabinet every success.”

Housing secretary Steve Reed, one of Starmer’s staunchest defenders, said he was “disappointed to be leaving government now”.

Kyle, who was business secretary, was another Starmer ally ousted as Burnham’s draws up his own top team.

Lord Hermer, who was Starmer’s attorney general, also said it had been “the privilege of my life to serve my country”.

“I will continue to support this Labour government from the backbenches, as it delivers the change this country desperately needs,” he said on Bluesky.

“Andy and his team know they have my utmost support and I wish them nothing but success.”

This is a breaking news story and will be updated. Follow HuffPost UK on Twitter, Facebook and Instagram.

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Who Is In Andy Burnham’s Government – And Who Is Out?

Andy Burnham has started to announce his ministerial picks on his first official day as prime minister.

The new PM is looking to draw a line in the sand between Keir Starmer’s government and his own, and so will likely root out those most closely linked to his predecessor.

However he has said he wants to run a more “collaborative” type of politics, suggesting he would be happy to have a range of ideologies in his top team.

Here’s what we know so far.

Cabinet Dismissals

Rachel Reeves has been sacked as the chancellor, having been closely tied to Starmer’s government and helped him enact any major economic policies.

She wrote on X: “I wish the very best of luck to my successor, Andy and his cabinet. You have my full support, and I will continue to play my part in helping this Labour government deliver the change the country needs.”

She was reportedly offered a role in Burnham’s government but turned it down.

Steve Reed was dismissed as housing and communities secretary, too.

He was loyal to Starmer to the very end so it is unsurprising he added a brutal parting shot for the new administration in his resignation letter.

The Labour MP wrote: “Keir Starmer showed loyalty to me by appointing me to his Cabinet. I make no apology for returning that loyalty. It’s what is expected of functioning teams, and I hope those who did not show loyalty to Keir will now show it to you.”

David Lammy was also kicked out of government after serving as deputy prime minister, justice secretary and previously his foreign secretary.

The Starmer loyalist wrote on X: “I would have been proud to continue serving in cabinet. But a new prime minister is entitled to build his own team, and I wish Andy Burnham and the new cabinet every success.”

Peter Kyle was also sacked as business secretary while Liz Kendall was fired as the work and pensions secretary.

Attorney General Lord Hermer and close friend to Starmer was kicked out, too, though he said the incoming government will have “my utmost support”.

The new prime minister is yet to confirm who he wants in his cabinet.

Wider Government

James Timpson, who was appointed to the Lords to serve as prisons and probation minister back in 2024, announced he was “retiring” today.

He spent longer in the post than anyone else appointed to the ministerial position over the last 15 years.

Science minster Patrick Vallance – and the government’s chief scientific adviser during the pandemic – quit on Monday morning, citing “personal reasons”.

It comes amid speculation the science department could be disbanded under Burnham.

This is a breaking news story. Check back for updates or follow HuffPost UK on X at @HuffPostUK or on Facebook.

Listen to Commons People, the podcast that makes politics easy. Every week, Kevin Schofield and Kate Nicholson unpack the week’s biggest stories to keep you informed. Join us for straightforward analysis of what’s going on at Westminster.

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