Beluga whales keep switching mates and it may be saving their species

Beluga whales are among the most challenging marine mammals to study. Much of their lives are spent beneath Arctic waters and sea ice, making direct observation difficult. Now, a long-term DNA study has provided rare insight into how a population of belugas in Bristol Bay, Alaska, forms family connections and maintains genetic health.

The findings suggest that both male and female belugas reproduce with multiple partners over the course of their lives. Researchers believe this behavior may help this relatively small and isolated population avoid inbreeding and preserve genetic diversity.

“We still know very little about beluga whales, despite their immense popularity,” said Dr. Greg O’Corry-Crowe of Florida Atlantic University, lead author of the paper in Frontiers in Marine Science. “The primary reason for this is the difficulty of studying a species that lives beneath the waves in the cold and often frozen north. But this is the challenge that makes discovery, when it happens, more exciting.”

Using DNA to Study Elusive Arctic Whales

Over a period of 13 years, researchers collected small tissue samples from 623 beluga whales. The project involved scientists from Florida Atlantic University, the Alaska Department of Fish and Game, and Alaska Native subsistence hunters from Bristol Bay.

Because little was known about mating patterns in wild belugas, the team developed predictions based on evolutionary theory and what scientists already knew about the species. For example, male belugas are noticeably larger than females, and females typically produce only one calf every few years.

“We predicted that beluga whales had a polygynous mating system where a few of the most competitive and possibly largest males secure most of the matings within a season or even across a few seasons, and that they provide little or no parental care,” said O’Corry-Crowe.

At the same time, belugas live in large social groups that regularly break apart and come back together. Researchers thought this social structure could give females access to many different potential mates over time. As a result, they predicted that females might reproduce with multiple males across different breeding seasons.

DNA Reveals Unexpected Mating Patterns

The genetic analysis produced a surprising result. Both males and females were found to have offspring with different partners over the years. When calves had siblings, they typically shared only one parent rather than both.

Although all whales produced relatively few offspring, there was greater variation among males. Some males fathered more calves than others, but the difference was not as extreme as researchers had expected.

“Beluga males were indeed polygynous, but, surprisingly, only moderately so,” said O’Corry-Crowe. “The three-dimensional aquatic environment likely limits a male’s ability to successfully court or corral multiple females. However, a long life may also be key. Belugas can live 90 years, possibly more. Male beluga whales may, therefore, play a long game of securing a few matings each year over a very long reproductive life!

“The female story is just as fascinating. The genetic profiling revealed that female belugas regularly switch mates across breeding seasons, also over a long reproductive life. This could be a bet-hedging strategy to limit the risk of mating with low-quality males.”

High Genetic Diversity in a Small Population

One of the most unexpected discoveries involved the population’s genetic health.

Despite numbering only about 2,000 individuals, the Bristol Bay belugas showed high levels of genetic diversity and relatively little evidence of inbreeding. Researchers compared the results with both historical samples and other beluga populations and found that genetic diversity in Bristol Bay is comparable to that of much larger populations. It has also remained stable over time.

“A leading concern for small populations is that they tend to lose genetic diversity faster than large populations and the risks of inbreeding are higher,” explained O’Corry-Crowe. “We expected to find low diversity and high inbreeding, but we found something quite different. The mating system may explain this surprising finding. Frequent mate switching limits the number of highly related offspring in the population. This in turn reduces the risk of highly related individuals mating and producing highly inbred offspring. It also minimizes the risk of diversity loss. We cannot afford to be complacent, but we can be optimistic that beluga whale mating strategies provide evidence of nature’s resilience.”

More Questions About Beluga Behavior

The researchers caution that other beluga populations may not behave in the same way.

Belugas in Bristol Bay show relatively small differences in size between males and females compared with some other populations. That could indicate lower levels of competition among males and potentially different mating systems elsewhere.

“To me, the differences in sexual dimorphism among populations of beluga whales could indicate that mating systems also vary, and this is something we are currently working on,” said O’Corry-Crowe. “We also can’t determine if females mate with multiple males within a season using genetics, as a female only produces one calf from one lucky male. But we are working on this, using drones at other locations to determine if we can observe mating behaviors in the wild. More on that soon…”

The study offers one of the clearest views yet into the hidden social lives of beluga whales. It also suggests that their flexible mating behavior may be helping these Arctic animals maintain strong genetic diversity despite living in a relatively small and isolated population.

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Scientists discover a quantum effect that could eliminate batteries

Scientists have uncovered a new way to control an unusual quantum phenomenon that could one day help power electronic devices without batteries.

An international research team led by Professor Dongchen Qi from the Queensland University of Technology (QUT) School of Chemistry and Physics and Professor Xiao Renshaw Wang from Nanyang Technological University in Singapore investigated the physics behind the nonlinear Hall effect (NLHE), a quantum phenomenon with significant potential for future energy-harvesting technologies.

Unlike the classical Hall effect, the NLHE can convert alternating electrical signals directly into direct current. This means energy from wireless transmissions or other ambient sources could potentially be transformed into usable electricity without relying on conventional diodes or other bulky electronic components.

“The NLHE is a sophisticated quantum phenomenon in condensed matter physics where a voltage is generated perpendicular to an applied alternating current, even in the absence of a magnetic field,” Professor Qi said.

“This effect allows us to convert alternating signals straight into direct current, which is what’s needed to power electronic devices. In principle, it means sensors or chips that could operate without batteries, drawing energy from their environment.”

Quantum Material Shows Stable Performance at Room Temperature

To better understand how the effect works, the researchers examined a high-quality topological material known for its unusual electronic behavior.

Their experiments showed that the nonlinear Hall effect remains stable even at room temperature, an important step toward practical applications outside the laboratory.

The team also discovered that temperature plays a key role in determining both the strength and direction of the electrical voltage produced by the material.

How Defects and Atomic Vibrations Control the Effect

At lower temperatures, tiny imperfections within the material had the greatest influence on the quantum effect. As temperatures increased, naturally occurring vibrations in the crystal structure became more important.

This shift caused the direction of the generated electrical signal to reverse, revealing a previously unseen mechanism for controlling the phenomenon.

“Once you understand what’s happening inside the material, you can design devices to take advantage of it,” Professor Qi said.

“That’s when quantum effects stop being abstract and start becoming useful — supporting future applications ranging from self-powered sensors and wearable technology to ultra-fast components for next-generation wireless networks.”

The findings provide new insight into how quantum materials behave and could help researchers develop smaller, faster, and more energy-efficient technologies that harvest power from their surroundings.

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‘I left a children’s home – and was embraced by love’

How a new scheme for young people leaving care is tackling what was once a cliff-edge for this vulnerable group.

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What a hair loss breakthrough could mean for women like me

As scientists edge closer to new treatments for hair loss, Victoria Derbyshire examines what such breakthroughs could mean for women.

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Breakthrough ovarian cancer drug offers patients more time and better quality of life

Women taking the drug, which is kinder on the body, tell the BBC it has given them their lives back.

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‘I Am An Old Man Who Lost His Butt Muscles And Has Back Problems’ — And This On-Sale Gadget Has Been A Game Changer

Studies show that low-impact exercise is especially beneficial for the physical and cognitive health of older adults. If you’re looking to get more movement in without putting undue pressure on your joints (or wallet), we spotted a compact, folding, low-impact stair stepper and climbing machine currently on sale for 15% off. Reviewers call the machine a welcome addition to their home setup, calling it “a great workout for an old man” and “a very significant aerobic workout, plus excellent low-impact strength development.” While it usually goes for close to $150, you can nab it today for under $130 — but you have to act fast — this is a lightning deal that ends soon.

Weighing under 30 pounds, the machine “folds into the size of an ironing board,” making it an easy addition to your home setup.

Made with alloy steel, this compact machine can help you move your legs, glutes and core without forceful landings on your feet, ankles and knees. The machine easily folds up, making it painless to store or move around your space. It can also hold up to 330 pounds.

When you’re ready to move, simply unfold the machine, adjust the handlebars, step height and stride length for intensity and comfort and move as fast or slow as you’d like, gliding your knees up and down. The digital interface tracks your speed, time, steps and calories, and there’s a spot for your phone to follow along with workouts.

“Space-saving design and light enough to transport and maneuver,” one wrote. “…The piston/hydraulic action is smooth and makes very little noise. For reference, I am 5′ 10″ and medium build, have no issues with knocking my knees on the pistons. The legs are sturdy as well and do not shake.”

Reviewers say this machine doesn’t just offer a solid cardio workout; it’s helping them rebuild strength and balance.

This climber lets you move fluidly, without harsh jumps or lifts; fans say it’s helping them regain their confidence while working out and feel physically stronger. Because it has no added resistance, you use your body weight and position to maintain the intensity, ensuring you always feel safe and in control.

“I am an old man who lost his butt muscles and was having back problems. This simple machine has been great for both problems and I’ve only had it a month,” one shopper wrote. “Sturdy, functional, easy to assemble and use-I could not recommend it more.”

66-year-old shopper Errin, who works a sitting desk job, got the machine “to strengthen my quads.” They say, “that set of muscles have gotten noticeably weaker as I’ve aged, and I could tell that the weak quads increased my fall risk. This stepper definitely targets quads! I use it a few times a day, about 50 steps each time. I really think it has helped already.”

Another reviewer, who enjoys the machine for indoor, all-weather fitness, says it’s also been great for their child who has self-described “neurological/motor issues.”

“It is kind of a challenge to find stuff for her to improve her strength and balance,” they wrote. “She uses this, too, and we started at doing ’10 steps’ each time, throughout the day. She’s doing 33 steps each session and does a few throughout the day, plus other activities that help her strength building and balance.”

Others love it for a “FULL BODY workout.

Per the American Sport And Fitness Association, “low-impact exercise” means movements that don’t have forceful landings or cause “shock absorption” in your joints — like running and jumping. Generally, these movements include having one foot on the ground (or pedal) at all times, making them a great option for older folks and people with mobility limitations, according to the National Library of Medicine.

While the machine certainly targets your bottom half, users say it’s surprisingly versatile, offering “a wide range of motion, depending on how you use it.” (Some even say it makes for great cross-training if you also like to use a rowing machine.)

“You can stand up straight on it, reach your arms into the air, and work your upper body and improve your balance. You could even add free weights. This is GREAT for improving your posture and core stability,” Eva wrote. “…If you stand up and lean back while holding the rails, and hunch over slightly, you can engage your abs. A nice bonus is that this stretches out your low back and gives it a little break.”

Reviewers say this folding climber is a step above the rest. Read more 5-star reviews and grab one on sale.

Best 100 bucks I ever spent. I am an old man who lost his butt muscles and was having back problems. This simple machine has been great for both problems and I’ve only had it a month. Sturdy, functional, easy to assemble and use- I could not recommend it more.” — Amazon customer

“1. Affordable 2. Space saving folds into size of an ironing board. 3. Adjustable – I’m a strong 270lb man and on the right settings was able to do a HIIT workout on this machine. Really tests cardio and builds strength in legs without knee strain or impact. At the same time this can be adjusted for grandmothers, kids, ladies doesn’t matter. Can’t recommend this highly enough. Been using it for 4mos and it’s very solid.” — Kevin

My mother bought something similar years ago, 1988. I utilized it with intent to see how long it would last from excessive use. It’s still in her basement and works. This Sunny equipment is well built and sturdy. If size, space, portability, and cost are issues, then this is the one for you. With proper form (slight squat) this will give you the burn and conditioning you’re after. I can watch TV while burning calories and attaining fitness. This will shape your buttocks, thighs, hips, calves, and more without breaking the bank for one of those steppers your see in the gym. I can take this anywhere, like outside and on the porch for fresh air and a good cardio session. I definitely like the longer cylinders for resistance and sleek design. Keep that towel and water bottle within reach, for you will get the burn with this low impact, blood pumping exercise!” — EdMenSal

“i have been using it about three weeks now. It was easy to put together, and very sturdy. I wanted something to strengthen my quads. That set of muscles have gotten noticeably weaker as I’ve aged, and I could tell that the weak quads increased my fall risk. I am 66 yrs old, female, in a desk job during the week, but fairly active on most weekends. (I ride and work with horses, stack hay, and do other work around a small farm.) This stepper definitely targets quads! I use it a few times a day, about 50 steps each time. I really think it has helped already.

July 22, 2020: I can hardly believe I’ve used this for over 5 years now! It’s as good as new despite almost daily use.” — Errin

The Real Deal: We use deal trackers and commerce experience to sift through “fake” hike-and-drop deals and other deceptive sales tactics. Products will usually be rated at least 4 stars with a minimum 15% discount. (And when there’s an exception, we’ll tell you why.)

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The Worst Health Habits You’re Probably Picking Up In Middle Age

Middle age is a time of life where there’s a lot going on.

Many in midlife are simultaneously responsible for the care of both elderly parents and young children (part of the so-called “sandwich generation”) while also facing the stresses of being mid-career and adjusting to the ways their bodies are changing.

There almost seems to be more to do in the same 24 hours during these years and, in turn, even less time for self-care.

But, unfortunately, skimping on that work of taking care of yourself can become normalized real quick — and it eventually adds up. In fact, the habits we pick up in middle age can have a direct effect on our long-term health and well-being.

In the spirit of longevity, HuffPost spoke to experts about the most common bad habits they see people develop in middle age — and what folks can do to turn things around.

Sorry, bed-rotters! Unfortunately, spending non-sleeping time in bed for too long can mess with your sleep schedule.

SushiSu via Getty Images

Sorry, bed-rotters! Unfortunately, spending non-sleeping time in bed for too long can mess with your sleep schedule.

Not Prioritizing Good, Restful Sleep

Dr. Ashley Cremona-Simmons, a board-certified family medicine physician and the founder of @DrCSEquityRX, told HuffPost that one of the most harmful things someone in middle age can do is lose sleep. In fact, she sees more patients complaining about the difficulty of getting a good night’s sleep as they approach middle age.

Cremona-Simmons said that patients should try to go to bed at the same time every night, aiming for 7-9 hours of sleep.

There are a few lifestyle changes she recommends to help support that goal: patients should avoid caffeine after morning and turn off screens to wind down before bedtime.

Cremona-Simmons also noted that habits like “bed rotting” can impact sleep too — and recommends that beds should only be used for shut-eye and intimacy.

She points patients to CDC recommendations that “they should look for signs of poor sleep quality.”

“They should tell their doctor if they have issues falling asleep, feel very tired after sleeping or repeatedly wake up during the night,” Cremona-Simmons said. “These could be symptoms of sleep disorders that need further management.”

Nutritional Setbacks

When life gets busy, it can often feel like there isn’t time to pull together a nutritious meal. That’s part of why adequate nutrition is one of the things that can easily fall off your radar in middle age, leading to less-than-great eating habits becoming the norm.

“There are so many recommendations surrounding what equates to adequate nutrition that it can be hard for patients to navigate,” said Cremona-Simmons. “Setting realistic goals increases the chance that the patient will actually meet them.”

Cremona-Simmons noted that maintaining a healthy weight can directly affect a patient’s likelihood of chronic disease in old age. Though genetics and environmental factors come into play, she always recommends a healthy diet for middle-aged patients. After all, it’s one element that they can control.

“I tell my patients to focus on eliminating processed foods as much as possible, focus on a varied diet with a lot of plant sources, and to increase consumption of fiber,” she said. “A diet heavy in plant sources and fermented foods helps maintain a proper gut biome.”

Not Moving Enough Or Moving Inconsistently

The benefits of physical activity are well-known, Cremona-Simmons said, noting that increasing exercise has been shown to improve muscle mass, symptoms of anxiety and depression, lower fasting glucose levels and more.

The CDC recommendation is for adults to aim for 150 minutes or more of moderate aerobic exercise and two days or more of strength training per week. After 65, they should also work on balance and mobility.

“I tell my patients to start with small goals, especially if they are relatively sedentary,” said Cremona-Simmons. “For example, they can start with just increasing their daily steps, taking the stairs instead of the elevator, or taking breaks to walk around their office building. The goal is to get moving!”

One of the biggest challenges middle-aged patients face is that they’re kind of at the peak of their lives where there are so many things they have to juggle, that it becomes really easy to push physical health to the side because other things require more immediate attention.

– Anna Di, chiropractor and owner of UNITY Chiropractic Wellness in New York City

Though physical activity is clearly vital for good health, Anna Di, a chiropractor and owner of UNITY Chiropractic Wellness in New York City, told HuffPost that it’s not enough to increase exercise one week and skip it the next. Instead, she said, a healthy movement routine hinges on a schedule.

“One of the biggest challenges middle-aged patients face is that they’re kind of at the peak of their lives, where there are so many things they have to juggle, that it becomes really easy to push physical health to the side because other things require more immediate attention,” said Di. “The budgeting of time to take care of your physical and mental health actually becomes even more important at this stage of life, but a lot of people do not realize that until symptoms start showing up.”

Di said accountability is hugely important when maintaining a consistent workout routine. It’s also important to try a range of movements, exercising different areas of the body.

“You are the doctor for that hour, treating yourself. That time is dedicated to getting better. Use this time to give yourself a good cardio workout, a patient but efficient stretch, or to do a few weight-training exercises,” she said. She added that trying new activities with a partner who can keep you accountable can also help prevent loneliness and, in turn, benefit mental health.

Not Addressing Pain When It Comes Up

Di said one of the worst things a middle-aged patient can do is ignore pain. When specific movements become difficult or painful, it’s not a sign to become less active but to seek out support.

“One analogy I like to use is if you are taking a hammer and hitting your thumb over and over and over, eventually once the hammer is gone, even the tiniest tap against your thumb or grazing the skin becomes extremely sensitive because of all the repetitive trauma that builds up over time,” said Di. “That does not mean you can never use a hammer again. It means you need to coordinate better so you stop hitting your thumb and start hitting the nail on the head.”

Ignoring or "playing through" the pain when it comes up instead of addressing it can lead to more issues in the long-term.

andreswd via Getty Images

Ignoring or “playing through” the pain when it comes up instead of addressing it can lead to more issues in the long-term.

She says beginning to move in ways that are not painful requires the conscious effort of “learning proper movement patterns, improving coordination, being patient with yourself during movement and sometimes working with specialists who can help guide you.”

“In middle age, sometimes the habits you had when you were younger really start to show. People notice that they are doing the same activities they used to do before, but now they do not recover as quickly, or they start feeling pain doing things that used to feel completely normal,” Di said. “A lot of people also lose confidence in movement because they are afraid of pain or reinjury.”

“But sometimes pain and bad habits happen because you do not yet have the strength, endurance, coordination, or even mental confidence to perform movements properly,” she continued.

Isolation And Loneliness

Though it may be harder to make new friends in middle age, it is still a prime time to form emotionally healthy relationships and build community, as Gwenyth Lloyd and Sarah Burrows, two mental health professionals at the SUNY New Paltz Psychological Counseling Center, told HuffPost.

Old age becomes a bit of a catch-22 when it comes to a social life. It can feel increasingly difficult to make friends out in the wild and to find the time to see the people you already know and love, but supportive relationships also have an increasingly central role in well-being at this age.

“If they have not cultivated those positive, healthy relationships, [people in middle age] can experience an intense sense of isolation,” Burrows said. “Social support is critical.”

The treatment for isolation is simply finding community and connection.

It can be as simple as striking up conversations with people outside or deeper, like building reliable social networks around things you care about, Lloyd noted, emphasizing how her own faith community created that space for her.

“Whether it’s at church, the community center, no man is an island,” Lloyd said. “We all need that stimulation. We all need to feel loved, to feel accepted.”

Substance Abuse

Lloyd said addictive behaviors can have a detrimental effect on mental health. In fact, substance abuse is considered a co-occurring disorder because of the way it affects the well-being of addicted people.

Overindulging in things like drugs, alcohol and even sex can cause patients to abandon the healthy and stable routines that actually benefit their mental and physical health.

It doesn’t help that things like alcohol just hit your body differently—with many people losing the enzyme that helps us metabolize alcohol (alcohol dehydrogenase) as we get older.

Excessive drinking, drug use or other less-than-healthy coping mechanisms require more attention (and intention) as you age.

Yuliia Kaveshnikova via Getty Images

Excessive drinking, drug use or other less-than-healthy coping mechanisms require more attention (and intention) as you age.

Developing A Negative Inner Voice

Most of us don’t consider the way we talk to and about ourselves when we’re thinking about health, but our outward behaviors are generally a manifestation of what’s happening inside.

And hopelessness begins when we are mean to ourselves, according to Burrows and Lloyd.

“Another bad habit can be how you think. Having a very negative outlook on life, a pessimistic and a very self-critical attitude, internally shaming, guilting, berating yourself, leads to depression and withdrawal, and even fear of connecting with others,” Burrows said.

Negative self-talk can be the result of trauma or family dynamics that were never addressed developmentally or in therapy, Lloyd notes. It results in poor interpersonal relationships, cycles of anger and, ultimately, a diminished quality of life.

But Burrows and Lloyd say cultivating more positive attitudes is something that can be developed at any age.

“The prescription is laugh heartily, smile regularly, and say hello to the world,” Lloyd said.

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Popular GLP-1 weight-loss drugs linked to lower risks of addiction and overdose

Popular GLP-1 drugs including Ozempic, Wegovy, Mounjaro, and Zepbound have already transformed the treatment of type 2 diabetes and obesity. Now, new research suggests these medications may also help prevent and treat addiction across a broad range of substances.

Researchers at Washington University School of Medicine in St. Louis found that GLP-1 medications were associated with lower risks of developing substance use disorders involving alcohol, nicotine, cannabis, cocaine, opioids, and other substances. The drugs were also linked to fewer overdoses, hospitalizations, and drug-related deaths among people already living with addiction.

The findings were published in The BMJ.

GLP-1 Drugs and Addiction

GLP-1 receptor agonists were originally developed to help manage type 2 diabetes, but their popularity has surged in recent years because of their effectiveness for weight loss. Along the way, researchers began noticing something unexpected.

Some patients reported losing interest in alcohol and cigarettes after starting the medications. Earlier observational studies also found links between GLP-1 treatment and lower risks of alcohol and cannabis use disorders, opioid overdose, and alcohol-related hospitalization.

However, most previous studies focused on individual substances. Researchers wanted to determine whether the effects extended across multiple forms of addiction and whether the drugs could help reduce the most serious consequences associated with substance use disorders.

To investigate, the research team analyzed electronic health records from 606,434 U.S. veterans with type 2 diabetes.

Study Examines More Than 600,000 Veterans

Participants were divided into two groups. One group included people without a substance use disorder at the start of the study. The second group consisted of people who already had a diagnosed substance use disorder.

Researchers reviewed up to three years of health records after participants began taking either a GLP-1 receptor agonist, most commonly semaglutide, liraglutide, or dulaglutide, or an SGLT2 inhibitor, another type of diabetes medication.

Among the 524,817 participants who did not have a substance use disorder when the study began, those taking GLP-1 medications were less likely to develop one over time.

Compared with patients taking non-GLP-1 diabetes medications, GLP-1 users had a 14% lower risk of developing any substance use disorder. Risks were lower across every major substance examined, including alcohol (18%), cannabis (14%), cocaine (20%), nicotine (20%), and opioids (25%).

The researchers estimated that this translated to seven fewer new substance use disorder diagnoses per 1,000 GLP-1 users.

Fewer Overdoses and Drug-Related Deaths

The study also examined outcomes among the 81,617 participants who already had a substance use disorder.

In that group, GLP-1 use was associated with fewer addiction-related emergencies and serious health consequences. After three years, participants taking GLP-1 drugs experienced a 30% reduction in emergency department visits, a 25% reduction in hospitalizations, a 40% reduction in overdoses, and a 50% reduction in drug-related deaths.

Overall, the researchers estimated that GLP-1 use was associated with 12 fewer serious addiction-related events per 1,000 users.

“In addiction medicine, a lot of treatments target just one thing, for example, a nicotine patch helps with smoking, but not alcohol, but there is no medication that works across addictive substances, let alone all of them,” said senior author Ziyad Al-Aly, MD, a WashU Medicine clinical epidemiologist and Chief of the Research and Development Service at the VA Saint Louis Health Care System.

“The revelation about GLP-1 medication is that it really works against all major substances, and it works uniformly, not because it acts against alcohol or opioids or nicotine specifically, but because it is likely acting against the craving itself. It blunts that craving that pulls people toward whatever they’re addicted to.”

Targeting the Biology of Craving

Al-Aly said the study was partly inspired by patient reports describing unexpected changes in behavior after starting GLP-1 treatment.

Researchers also considered evidence showing that GLP-1 receptors are present in brain regions involved in reward processing. That raised the possibility that the drugs could influence the cravings that drive addiction.

The findings suggest that GLP-1 medications may act on a shared biological pathway underlying multiple forms of addiction. Rather than targeting a specific substance, the drugs may be affecting the craving itself.

The idea is particularly significant because some addictive substances, including methamphetamine, currently have no approved medication treatments.

“GLP-1s may offer a dual benefit for patients with chronic conditions like diabetes or obesity who are also struggling with a substance use disorder: one medication can treat both conditions at once,” Al-Aly said.

A Potential New Approach to Addiction Treatment

Millions of Americans already use GLP-1 medications, and that number continues to grow. If future studies confirm these findings, the public health implications could be substantial.

The researchers say the results support conducting clinical trials specifically designed to test GLP-1 drugs as addiction treatments, including studies capable of measuring effects on overdose and drug-related death.

“People taking these drugs for obesity often describe a quieting of ‘food noise,’ the persistent preoccupation with food that drives overeating,” Al-Aly said.

“What our study suggests is something broader: GLP-1 drugs may also quiet what I call ‘drug noise,’ the relentless craving that drives addiction across substances. That cross-substance signal points to a shared biology underlying addiction, and it opens the door to a fundamentally different approach: not treating one addiction at a time, but targeting that common biologic signal, that common craving across addictions. Moving beyond food noise to drug noise, GLP-1s are quieting the roar of addiction.”

The research was funded by the U.S. Department of Veterans Affairs. According to the authors, the funders had no role in the study’s design, data collection, analysis, interpretation, manuscript preparation, review, approval, or publication decisions. The researchers also noted that the findings do not represent the views of the Department of Veterans Affairs or the U.S. government.

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Can two hours of strength training a week reduce the risk of dying early?

Regular weight training can help you keep fit and strengthen muscles to live longer, research suggests.

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What are the plans for Liverpool Women’s Hospital?

There are plans to move some maternity services to the Royal Liverpool – which could affect around 130 high-risk births each year

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