NASA study finds ancient life could survive 50 million years in Martian ice

Future missions to Mars may want to dig into ice rather than rock. Scientists say ancient microbes, or traces of them, could be locked inside Martian ice deposits, preserved for tens of millions of years.

Researchers from NASA Goddard Space Flight Center and Penn State recreated Mars like conditions in the laboratory to test that idea. They found that pieces of amino acids from E. coli bacteria, if trapped in Martian permafrost or ice caps, could survive more than 50 million years even under constant cosmic radiation. The findings, published in Astrobiology, suggest that missions searching for life on Mars should prioritize pure ice or ice rich permafrost instead of focusing mainly on rocks, clay, or soil.

“Fifty million years is far greater than the expected age for some current surface ice deposits on Mars, which are often less than two million years old, meaning any organic life present within the ice would be preserved,” said co author Christopher House, professor of geosciences, affiliate of the Huck Institutes of the Life Sciences and the Earth and Environment Systems Institute, and director of the Penn State Consortium for Planetary and Exoplanetary Science and Technology. “That means if there are bacteria near the surface of Mars, future missions can find it.”

Simulating Mars and Cosmic Radiation in the Lab

The study was led by Alexander Pavlov, a space scientist at NASA Goddard who completed a doctorate in geosciences at Penn State in 2001. The team sealed E. coli bacteria inside test tubes filled with pure water ice. Other samples were combined with water and materials commonly found in Martian sediment, including silicate based rocks and clay.

The frozen samples were placed in a gamma radiation chamber at Penn State’s Radiation Science and Engineering Center. The chamber was cooled to minus 60 degrees Fahrenheit to match temperatures in icy regions of Mars. The bacteria were then exposed to radiation equivalent to 20 million years of cosmic ray bombardment on the Martian surface. Afterward, the samples were vacuum sealed and shipped back to NASA Goddard under cold conditions for amino acid testing. Researchers then modeled an additional 30 years of radiation exposure, bringing the total to 50 million years.

Pure Ice Protects Organic Molecules

The results were striking. In pure water ice, more than 10 percent of the amino acids, which are the building blocks of proteins, survived the full 50 million year simulation. By contrast, samples mixed with Mars like sediment broke down 10 times faster and did not survive.

A 2022 study by the same team had shown that amino acids preserved in a mixture of 10% water ice and 90% Martian soil were destroyed more quickly than samples containing only sediment.

“Based on the 2022 study findings, it was thought that organic material in ice or water alone would be destroyed even more rapidly than the 10% water mixture,” Pavlov said. “So, it was surprising to find that the organic materials placed in water ice alone are destroyed at a much slower rate than the samples containing water and soil.”

Researchers think the faster breakdown in mixed samples may happen because a thin film forms where ice touches minerals. That layer could allow radiation to move more freely and damage amino acids.

“While in solid ice, harmful particles created by radiation get frozen in place and may not be able to reach organic compounds,” Pavlov said. “These results suggest that pure ice or ice-dominated regions are an ideal place to look for recent biological material on Mars.”

Implications for Europa and Enceladus

The team also tested organic material at temperatures similar to those on Europa, an icy moon of Jupiter, and Enceladus, an icy moon of Saturn. At those even colder temperatures, deterioration slowed down further.

Pavlov said the findings are encouraging for NASA’s Europa Clipper mission, which will study Europa’s ice shell and subsurface ocean. Europa is the fourth largest of Jupiter’s 95 moons. Europa Clipper launched in 2024 and is traveling 1.8 billion miles to reach Jupiter in 2030. The spacecraft will perform 49 close flybys to determine whether environments beneath the surface could support life.

Drilling Into Martian Ice

When it comes to Mars, accessing buried ice will require the right tools. The 2008 NASA Mars Phoenix mission was the first to dig down and photograph ice in the Martian equivalent of the Arctic Circle.

“There is a lot of ice on Mars, but most of it is just below the surface,” House said. “Future missions need a large enough drill or a powerful scoop to access it, similar to the design and capabilities of Phoenix.”

In addition to House and Pavlov, the research team included Zhidan Zhang, a retired lab technologist in the Penn State Department of Geosciences, along with Hannah McLain, Kendra Farnsworth, Daniel Glavin, Jamie Elsila, and Jason Dworkin of NASA Goddard.

The work was funded by NASA’s Planetary Science Division Internal Scientist Funding Program through the Fundamental Laboratory Research work package at Goddard Space Flight Center.

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This $20 Hair Mask Made My 60-Something Straw-Like Hair Feel ‘Like Silk Again’

Whether your hair has thinned with age or is hurting from heat damage, you may think fixing will require lots of dough and extra salon trips. Lucky for you, we spotted a collagen and argan oil hair mask from the brand Karseell, which reviewers deem “a five-star professional experience delivered in a jar.”

The at-home mask is made with a blend of nourishing oils, proteins and herbal extracts. Easily used in the shower, it’ll save you the time, effort and inconvenience of leaving home. It’s also currently on sale for 20% off, the lowest price it’s been in weeks, saving you some precious coins, too.

Reviewers say this creamy, dreamy mask “turns back the clock” on their strands, repairing damage they thought was permanent and making hair feel *Madonna voice* “like a virgin again…”

Teresita Rodriguez Bermùdez professes that it’s a “worth every penny” mask and far more than a conditioner; “it is a total hair transformation.”

“My hair went from being dry and brittle to feeling incredibly silky, hydrated and full of life,” they wrote, calling the mask “the gold standard” for high-end hair restoration treatments.

Made with an active collagen blend, wheat and soy proteins, shea butter, and chamomile extract — the coconut-scented mask is equal parts strengthening, soothing and shine-producing. (Note: The mask has wheat in it so it’s NOT gluten-free, for those with allergies and severe sensitivities.)

It’s also incredibly easy to incorporate into your routine without over-complicating it.

Unlike lengthy, often noxious salon strengthening sessions, this at-home mask functions almost like a conditioner. The brand recommends applying it weekly to washed, towel-dried hair, spreading the mask from root to tip, letting it hang for 5-10 minutes and then rinsing. For a longer “mask” feel, some reviewers leave it on all night, “resulting in noticeably softer and smoother hair the next morning,” one said. Yet many reviewers report using it as they would a normal conditioner, for about 3 minutes while showering.

To make the container last longer and keep their routines quick, some reviewers say they mix the mask in with their normal conditioner for a little extra oomph. Another reviewer with type 3C natural hair used the mask before flat-ironing their hair. “My hair is frizz free, silky and has a salon look,” they wrote. “I will buy again. I’m hoping to be frizz free for at least a week.”

Like many brands, Karseell’s mask is designed for all hair types but unlike a lot of those — people with varying hair types and those with different hair challenges say this brought their hair back to life.

Those with menopause, hormonal changes, and general age-related hair changes vouch for the mask strengthening and restoring their strands.

″…One application and my hair is no longer dry and brittle,” a shopper in their 60s said. ”…It’s now soft and feels like it has life back in it!” A user almost 70 calls the mask “the greatest” they’ve ever found, noting it made their straw-like hair feel “like silk again.”

People with color- and chemically-treated hair, “dry and brittle” hair after going through chemo, those who use a lot of hot tools, or who just crave a “mirror-like” shine and frizz management.

It’s also loved by users for helping revive curls. One grandparent calls the mask “miracle in a jar,” for their 16-year-old grandson’s hair.

″…With the application of this product, detailing wasn’t bad and I could see his natural curl pattern shine through,” they wrote. ”…It was the first time in ages that I had seen his hair curl definition…”

Reviewers love this collagen and argan oil hair mask for making their strands smooth and strong. Read more 5-star reviews and take advantage of this great sale.

“This product is very good. I felt like I went to the spa. I am a 67 year old female, with 3 inches below shoulder length, very dry and thinning hair. So opposite of what I used to have. I do not want to start cutting my hair short yet. I have tried dozens and dozens of products over the years. I can honestly say that Karseell hair treatment is by far, the best that I have used. Very easy to use. My hair feels and looks like I turned the clock back. My hair feels softer and more youthful. I only used it once so far, but what a difference. It’s a much try product.” — Amazon customer

My hair is straight, thin, and over-dyed for going on 3 decades. I skip hair trims. I like to use cheap hair dye & dry shampoo & heated tools. My hair usually goes up in a hair-clip as soon as I get up. Saying all that… this conditioner, after one use, made my hair feel like a virgin again… like super soft & shiny & with volume! I don’t understand the science of products and maybe this just coats my hair in a temporary silky substance, but it feels so good & I love it. I just put it on after shampooing & let it stay as long as I can find other things to do in the shower (so like 3 mins?) If one were to leave it on longer as the bottle suggests … holy moly… bet it’s amazing. It works for my hair.” — Jess

“This conditioner is absolutely amazing. I have very dry hair due to menopause and it’s left my hair smooth and glossy. I use it twice a week for best results.” —Brigitte Elzarki

Amazon

Hair-building fibers

Reviewers call this bottle of hair-building fibers “a best kept secret” for making hair appear instantly thicker while also concealing bald spots and grays. The fibers, which are made of a keratin protein, work by clinging to existing hair strands for a seamless look and a performance that’s resistant to rain, wind or sweat. It’s available in nine hair colors.

Promising Amazon reviews:Amazing best kept secret! Most folks have never heard of these hair fibers but they really work! When I pull my hair back into a pony tail, the baby hair along the front of my face is thin and a few gray hairs popping in. All you see is my scalp and looks bad so I ordered these hair fibers and with a little sprinkle, you can not see the obvious part that looks like a bald spot!
My husband uses the gray fiber because he has some thinning on the top of his scalp. The hair fibers makes his hair look so much fuller and can’t see through to his scalp! We both do not use it on a daily basis. Just when we know we will be taking pictures and/or social events. No gimmicks here…works like a charm! A little sprinkle goes a long way! Highly recommend!” — Penny T.

“My hair has thinned around my temples and this product was recommended to me by my hair stylist. I love it! It allows me to wear my hair up it a pony tail without looking thin around the hairline. It’s also great for when my gray roots start coming in and I have a couple days until my next hair appointment. Life saver!” — Jackie Gringle

Sephora

A peptide-infused shampoo for thinning hair

This gentle purifying shampoo claims to visibly thicken and strengthen hair from root to tip using, while also eliminating buildup on the scalp. Hyaluronic acid hydrates and thickens, while ceramides aid in promoting strand elasticity and a gluco-peptide reduces future breakage and hair is strong enough to grow.

Promising Sephora review: “”Definitely stuck on this one now! This makes my hair look and feel thicker and it makes it feel soft too. There’s no gross smell or feel when you use it and I think it’s worth the price.” — kilianm

Amazon

A root cover spray

This popular hair spray is marketed as a solution to temporarily cover grays in between dye jobs, but reviewers also claim that it can help make hair appear thicker by concealing areas where hair is thinner and the scalp is more noticeable. The lightweight formula claims to be water- and smudge-resistant, residue-free and quick-drying. It comes in up to 11 shades that wash out easily on your next shampoo.

Promising Amazon review:I’m a senior with thinning hair and this spray works great. Just be sure to hold it only 4″ approx from your scalp and spray for2-3 seconds and move to a new spot on your head where your scalp is showing thru or your roots are showing. Don’t hold too far away from your scalp and don’t hold it in one spot. It will feel cold, but that stops almost as soon as you are done spraying that spot. It dries in min. It also thickens your hair so your hair will look fuller. Your fingers may get a little spray on them, but it washes right off with a bit of soap. Also this does wash out if you don’t like it. It washes out easily.” — Jan S-dell

Amazon

A weightless volumizing mousse

This isn’t the first notable product from Color Wow, the hair care brand known for the viral Dream Coat anti-humidity spray. The Xtra Large Bombshell Volumizer is a weightless pre-styling foam that’s made from a proprietary polymer and bamboo that thickens tresses and adds a flexible body. The non-drying formula also doubles as a heat-protectant and promises to leave a glossy and bouncy finish that’s free from any sticky residue.

Promising Amazon reviews: “I have tried many products for thin hair but this is the first one that actually worked. My hair looks so much better and thicker and it even looks almost cute when I wake up in the morning because it’s going everywhere and looking thick. That is a first I am now a regular customer” — Theresa Bailey

Amazon

A pre-styling thickening tonic

Aveda’s thickening tonic claims to expand hair strands from root to tip using an organic wheat-based and botanical formula. Just apply the product on towel-dried hair prior to styling for a result that can add visual fullness to tresses in just one use.

Promising Nordstrom review: “I was skeptical and had to think about it a couple of weeks before I ordered. As I age my hair is really thinning to the point you can see my scalp. I have used the Aveda Thickening Tonic daily for a week and I can notice a difference when I use a blow dryer and lightly dry it then shake the bottle well and apply it. I tried applying it to damp, towel dried hair but didn’t get as good results as when I lightly dried it. I will purchase again, so that is a great recommendation from me!” — MeMe4AnJ

The Real Deal: We use deal trackers and commerce experience to sift through “fake” hike-and-drop deals and other deceptive sales tactics. Products will usually be rated at least 4 stars with a minimum 15% discount. (And when there’s an exception, we’ll tell you why.)

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GPs told to guarantee same-day appointments for urgent cases

New contract will require patients in England to be given immediate appointment if needed.

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Something strange is happening in the Milky Way’s magnetic field

For generations, scientists have studied the stars and planets to better understand how our galaxy works. Now, Dr. Jo-Anne Brown, PhD, is focused on charting something we cannot see at all: the Milky Way’s magnetic field.

“Without a magnetic field, the galaxy would collapse in on itself due to gravity,” says Brown, a professor in the Department of Physics and Astronomy at the University of Calgary.

“We need to know what the magnetic field of the galaxy looks like now, so we can create accurate models that predict how it will evolve.”

New Milky Way Magnetic Field Data and Models

This month, Brown and her colleagues published two new studies in The Astrophysical Journal and The Astrophysical Journal Supplement Series. Together, the papers introduce a complete dataset that astronomers around the world can use, along with a new model designed to improve understanding of how the Milky Way’s magnetic field developed over time.

To gather the data, the team relied on a new radio telescope at the Dominion Radio Astrophysical Observatory in B.C., a National Research Council Canada facility. The instrument allowed them to scan the northern sky at multiple radio frequencies, offering a detailed look at the structure of the galaxy’s magnetic field.

“The broad coverage really lets you get at the details about the magnetic field structure,” says Dr. Anna Ordog, PhD, lead author of the first study.

The result is a high quality, wide ranging dataset collected as part of the Global Magneto-Ionic Medium Survey (GMIMS), an international effort to chart the Milky Way’s magnetic field.

Tracking Faraday Rotation Across the Galaxy

The researchers measured a phenomenon known as Faraday rotation to trace the magnetic field. This effect occurs when radio waves pass through regions filled with electrons and magnetic fields, causing the waves to shift.

“You can think of it like refraction. A straw in a glass of water looks bent because of how light interacts with matter,” says Rebecca Booth, a PhD candidate working with Brown and lead author of the second study. “Faraday rotation is a similar concept, but it’s electrons and magnetic fields in space interacting with radio waves.”

By analyzing these subtle changes in radio signals, the team was able to map how the magnetic field is arranged across vast stretches of the galaxy.

A Diagonal Magnetic Reversal in the Sagittarius Arm

In the second study, Booth focused on a striking feature within the Milky Way known as the Sagittarius Arm, where the magnetic field runs in the opposite direction compared to the rest of the galaxy.

“If you could look at the galaxy from above, the overall magnetic field is going clockwise,” says Brown. “But, in the Sagittarius Arm, it’s going counterclockwise. We didn’t understand how the transition occurred. Then one day, Anna brought in some data, and I went, ‘O.M.G., the reversal’s diagonal!'”

Building on Ordog’s findings, Booth used the newly assembled dataset to construct a three dimensional model explaining this reversal.

“My work presents a new three-dimensional model for the magnetic field reversal. From Earth, this would appear as the diagonal that we observe in the data,” Booth explains.

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Can solar storms trigger earthquakes? Scientists propose surprising link

Scientists at Kyoto University have developed a theoretical model examining whether disturbances in the ionosphere could apply electrostatic forces deep within the Earth’s crust. Under certain conditions, these forces might contribute to the start of large earthquakes.

The research is not designed to forecast earthquakes. Instead, it outlines a possible physical mechanism showing how shifts in ionospheric charge levels — triggered by intense solar activity such as solar flares — might interact with already weakened areas of the crust and influence how fractures develop.

How the Ionosphere Could Affect Fault Zones

In this model, cracked regions of the crust are thought to contain water at extremely high temperatures and pressures, possibly in a supercritical state. Electrically, these fractured zones may act like capacitors. They are coupled both to the Earth’s surface and to the lower ionosphere, creating a vast electrostatic system that links the ground to the upper atmosphere.

When solar activity surges, electron density in the ionosphere can rise significantly. This can produce a negatively charged layer in the lower ionosphere. Through capacitive coupling, that charge may generate intense electric fields inside microscopic voids within fractured rock. The resulting electrostatic pressure could approach levels similar to tidal or gravitational stresses that are already known to influence fault stability.

According to the team’s calculations, ionospheric disturbances tied to major solar flares — involving increases in total electron content of several tens of TEC units — might create electrostatic pressures of several megapascals within these crustal voids.

Ionospheric Anomalies Observed Before Major Quakes

Unusual ionospheric behavior has often been detected before powerful earthquakes. Observations have included spikes in electron density, drops in ionospheric altitude, and slower propagation of medium-scale traveling ionospheric disturbances. Traditionally, scientists have interpreted these changes as effects caused by stress building up inside the crust.

This new framework offers an additional perspective. It suggests a two way interaction in which processes inside the Earth can influence the ionosphere, while ionospheric disturbances may also send feedback forces back down into the crust. The model connects space weather and seismic activity without claiming that solar activity directly causes earthquakes.

Solar Activity and the 2024 Noto Peninsula Earthquake

The researchers point to recent major earthquakes in Japan, including the 2024 Noto Peninsula earthquake, as events that occurred shortly after periods of intense solar flare activity. They stress that this timing does not prove cause and effect. However, it aligns with the idea that ionospheric disturbances could act as a contributing factor when faults are already close to failure.

Rethinking Earthquakes Beyond Internal Forces

By drawing on plasma physics, atmospheric science, and geophysics, this approach expands the traditional view that earthquakes are driven solely by forces inside the planet. The findings indicate that tracking ionospheric conditions alongside underground measurements could improve understanding of how earthquakes begin and how seismic risk is assessed.

Future work will combine high-resolution GNSS-based ionospheric tomography with detailed space weather data. The goal is to determine when and how ionospheric disturbances might exert meaningful electrostatic effects on the Earth’s crust.

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190-million-year-old “Sword Dragon” fossil rewrites ichthyosaur history

A remarkably complete skeleton uncovered along the UK’s Jurassic Coast has been identified as a previously unknown species of ichthyosaur — a group of prehistoric marine reptiles that once dominated the world’s oceans.

The dolphin-sized creature, named Xiphodracon goldencapensis and nicknamed the “Sword Dragon of Dorset,” is the only known specimen of its species. Its discovery helps close a major gap in the fossil record and offers new insight into ichthyosaur evolution.

For more than two centuries, the Jurassic Coast has yielded thousands of ichthyosaur fossils, ever since pioneering fossil hunter Mary Anning began making historic finds there. However, this marks the first new genus of Early Jurassic ichthyosaur described from the region in more than 100 years.

Exceptionally Preserved 190-Million-Year-Old Fossil

The fossil was found near Golden Cap in 2001 by Dorset collector Chris Moore. Preserved in nearly perfect three-dimensional detail, the skeleton includes a skull with a huge eye socket and an elongated, sword-like snout. Researchers estimate the animal measured about three meters long and likely fed on fish and squid. There may even be traces of its final meal preserved within the remains. It is thought to be the most complete prehistoric reptile ever discovered from the Pliensbachian period.

The research was carried out by an international team of paleontologists led by ichthyosaur specialist Dr. Dean Lomax, an Honorary Research Fellow at The University of Manchester and an 1851 Research Fellow at the University of Bristol. Their findings appear in the journal Papers in Palaeontology.

Dr. Lomax said: “I remember seeing the skeleton for the first time in 2016. Back then, I knew it was unusual, but I did not expect it to play such a pivotal role in helping to fill a gap in our understanding of a complex faunal turnover during the Pliensbachian. This time is pretty crucial for ichthyosaurs as several families went extinct and new families emerged, yet Xiphodracon is something you might call a “missing piece of the ichthyosaur puzzle.” It is more closely related to species in the later Early Jurassic (in the Toarcian), and its discovery helps pinpoint when the faunal turnover occurred, being much earlier than expected.”

Solving an Evolutionary Mystery

After it was collected in 2001, the skeleton was acquired by the Royal Ontario Museum in Canada, where it joined one of the world’s largest ichthyosaur collections. Despite its importance, it had remained unstudied until now.

Ichthyosaurs from the Pliensbachian (193-184 million years ago) are extremely rare, making this specimen especially valuable. Scientists have long known that ichthyosaur species before and after this time period were very different from one another, even though they occupied similar ecological roles.

Co-author Professor Judy Massare of the State University of NY at Brockport explained: “Thousands of complete or nearly complete ichthyosaur skeletons are known from strata before and after the Pliensbachian. The two faunas are quite distinct, with no species in common, even though the overall ecology is similar. Clearly, a major change in species diversity occurred sometime in the Pliensbachian. Xiphodracon helps to determine when the change occurred, but we still don’t know why.”

Evidence of Injury and a Violent End

The skeleton also provides clues about the challenges of life in Jurassic seas. According to co-author Dr. Erin Maxwell of the State Museum of Natural History Stuttgart, several limb bones and teeth show abnormalities that suggest the animal suffered serious injury or illness while it was alive. The skull also appears to bear bite marks from a much larger predator — likely another large ichthyosaur — which may have caused its death.

Dr. Maxwell said: “This skeleton provides critical information for understanding ichthyosaur evolution, but also contributes to our understanding of what life must have been like in the Jurassic seas of Britain. The limb bones and teeth are malformed in such a way that points to serious injury or disease while the animal was still alive, and the skull appears to have been bitten by a large predator — likely another much larger species of ichthyosaur — giving us a cause of death for this individual. Life in the Mesozoic oceans was a dangerous prospect.”

Unique Features and a Fitting Name

Researchers identified several anatomical traits in Xiphodracon that have never been documented in any other ichthyosaur. One of the most unusual features is a distinctive bone near the nostril (called a lacrimal) that includes prong-like projections.

Dr. Lomax, author of the recent book “The Secret Lives of Dinosaurs,” said: “One of the coolest things about identifying a new species is that you get to name it! We opted for Xiphodracon because of the long, sword-like snout (xipho from Greek xiphos for sword) and dracon (Greek and Latin for dragon) in reference to ichthyosaurs being referred to as “sea dragons” for over 200 years.”

The study was published in the international journal Papers in Palaeontology. The fossil is expected to go on public display at the Royal Ontario Museum in Toronto, Canada.

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Do Exosomes Live Up To Their Anti-Aging Claims? Here’s What Dermatologists Say.

If you’re on the lookout for the latest skin care ingredient that can smooth and plump your complexion, you’ve probably seen influencers talking about exosomes, which claim to offer a wealth of anti-aging benefits. But before you buy into the hype, have you really thought about what they are, and whether they’re effective?

Exosomes are tiny, naturally occurring vesicles that skin and other types of cells release. They transport bioactive molecules (think: peptides, fats and proteins) to other cells, explained Dr. Jacob Beer, a dermatologist at Beer Dermatology in West Palm Beach, Florida.

There are dozens of serums, creams and other skin care products, some selling for hundreds of dollars, that contain exosomes, and medical spas often incorporate them into procedures like microneedling and laser treatments. But it’s important to note that exosomes are not approved by the Food and Drug Administration for cosmetic use.

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Exosomes are a misunderstood skin care trend, though, since their behavior varies widely depending on their source and what they’re transporting, according to the experts we spoke to.

Still, exosomes “show promise” for skin rejuvenation, Beer said. “It’s important to just remember that not all exosomes are the same, not all preparations are the same, and some formulations have more data than others.”

Here’s what to know about exosomes and their potential benefits and risks.

What are exosomes, exactly?

Think of exosomes as tiny “message bubbles that cells send to each other,” explained Dr. Jennifer Holman, a dermatologist with U.S. Dermatology Partners Tyler in Texas. The bubbles contain instructions (in the form of proteins, growth signals and genetic material) that “tell cells how they should behave.”

They can be derived from different sources, such as platelets, stem cells, fat or plants, and carry “biologically active messenger cargo,” such as proteins, lipids or signaling molecules, added Dr. Krishna Vyas, a plastic surgeon in New York City. Those instructions can potentially influence inflammation, repair, recovery and regeneration in the “recipient cells.”

The skin benefits of exosomes.

Some exosomes have been studied more than others, and much of the research has involved small patient samples or hasn’t been done on human subjects, Beer said.

“Not all exosomes are created equal, as they don’t contain the same instructions,” Holman said, so their effectiveness depends on what’s inside the bubble.

Take platelet-derived exosomes, for example. Platelets are cells that are drawn to areas of injury and help the body heal. Holman said platelet-derived exosomes are tiny and combine with or dissolve in fats, so they can be applied topically and tell the skin to heal itself.

Some studies have shown that exosomes applied topically can lead to “collagen production, repair of elastin and new elastin production, decreased inflammation and redness, and speeds post procedural healing time,” Holman said.

Vyas noted: “These effects are thought to occur through regulation of inflammatory pathways and activation of fibroblasts, the cells responsible for collagen and elastin synthesis.”

Exosomes are also sometimes applied to the skin after microneedling, a treatment that uses tiny needles to treat acne scars, wrinkles and sagging skin. Vyas said this approach may enhance the topical penetration of exosomes. While this is an off-label use and potentially risky, a small study suggests that pairing exosomes and microneedling could reduce pore size and improve skin texture.

However, since there are no long-term, randomized clinical trials on exosomes, Vyas said their benefits should be considered “as promising but not conclusively established.”

Are exosomes safe?

Redness and irritation are commonly reported side effects of topical exosomes, Beer said. Those usually go away once you stop using the products.

However, when exosomes are administered with microneedling or injected into the skin (which is done in some medical spas), “all bets are off,” Beer said. There are cases of patients developing scars, discoloration, mycobacterial infections, or an immune response known as a granuloma.

“The greater concern lies in uncertainty surrounding long-term safety, repeated use and product consistency,” Vyas said.

Since exosomes are derived from different sources, there’s a lot of variability in products that makes quality control, reproducibility and safety challenging, he added. Exosomes aren’t FDA-approved for medical or cosmetic use in the U.S. So there’s no universal quality standard for products containing them, Holman said.

“Exosomes can be sold under cosmetic regulations as long as they are not making therapeutic claims,” Holman said.

Should you use exosomes?

Serums and moisturizers containing exosomes for topical use are mostly safe, Beer said.

Still, it’s difficult to know what type of exosome products contain or how they’re sourced because they’re not subject to the FDA’s labeling requirements, Vyas said. Some may make exaggerated claims about the product’s benefits, Holman noted. In South Korea, officials recently started prohibiting the term “exosomes” as a cosmetic advertising term to prevent misleading claims.

However, when it comes to injecting exosomes or pairing them with microneedling, Beer said, “I avoid that like the plague.”

Many providers don’t understand what exosomes are, the data behind them, or what can go wrong with their use (such as infections or immune reactions), Beer added. “I counsel my patients to avoid injecting or microneedling exosomes until we have better data because, however expensive the treatment was, it will likely be much more to correct it later.”

Complications from these procedures could mean numerous laser treatments to treat discoloration and scarring, for example, he noted.

Because of the variability of products, lack of transparency, and limited scientific data, Vyas said, “Exosome-based aesthetic products should be considered investigational rather than established therapies.”

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GPs to get £3,000 bonus to maximise weight loss drug prescriptions

Bid to improve access to Mounjaro in England, but experts warn eligibility still tightly restricted.

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First British baby born using transplanted womb from dead donor

Grace Bell, who was born without a viable womb, says her little boy is “simply a miracle”.

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A hidden force beneath the Atlantic ripped open a 500 kilometer canyon

On land, dramatic canyons such as the Grand Canyon are carved over time by flowing rivers. The ocean does not have rivers capable of cutting into rock on that scale. Even so, the seafloor hosts enormous features that surpass the size of the largest land canyons.

About 1,000 kilometers off the coast of Portugal lies one of the most striking examples. Known as the King’s Trough Complex, this vast underwater structure stretches roughly 500 kilometers and includes a series of parallel trenches and deep basins. At its eastern edge is Peake Deep, one of the deepest locations in the Atlantic Ocean.

What created such an immense formation? A team of international researchers led by the GEOMAR Helmholtz Centre for Ocean Research Kiel has uncovered new clues. Their findings appear in Geochemistry, Geophysics, Geosystems (G-Cubed), published by the American Geophysical Union (AGU).

“Researchers have long suspected that tectonic processes — that is, movements of the Earth’s crust — played a central role in the formation of the King’s Trough,” says lead author Dr. Antje Dürkefälden, marine geologist at GEOMAR. “Our results now explain for the first time why this remarkable structure developed precisely at this location.”

Seafloor Rifting Between Europe and Africa

The new research indicates that between about 37 and 24 million years ago, a plate boundary separating Europe and Africa temporarily passed through this part of the North Atlantic. As the tectonic plates shifted, the crust in this region was pulled apart and fractured, opening progressively from east to west, much like a zipper being undone.

An important piece of the puzzle lies even deeper. Before the plate boundary moved into the area, the oceanic crust there had already become unusually thick and heated. This condition resulted from hot material rising upward from Earth’s mantle. Known as a mantle plume, this steady column of molten rock originates far below the surface. The team believes this was an early offshoot of what is now the Azores mantle plume.

“This thickened, heated crust may have made the region mechanically weaker, so that the plate boundary preferentially shifted here,” explains co-author PD Dr. Jörg Geldmacher, marine geologist at GEOMAR. “When the plate boundary later moved further south towards the modern Azores, the formation of the King’s Trough also came to a halt.”

How Mantle Activity Shapes the Atlantic

The King’s Trough offers a clear example of how deep mantle processes and shifting tectonic plates interact. Activity far below the surface can prepare the crust for later deformation, influencing where major fractures and rifts eventually develop.

These findings also shed light on the broader geodynamic history of the Atlantic Ocean. Similar processes may still be underway today. Near the Azores, a comparable trench system called the Terceira Rift is forming in another region where the oceanic crust is unusually thick.

Mapping the King’s Trough

The conclusions are based on data collected during research expedition M168 aboard the research vessel METEOR in 2020, led by Antje Dürkefälden. The scientists used high resolution sonar to produce a detailed map of the seafloor. They then retrieved volcanic rock samples from several parts of the trench system using a chain bag dredge.

Back in the lab, the team examined the chemical makeup of the rocks. Selected samples were dated at the University of Madison (Wisconsin, USA). Additional bathymetric data came from the Portuguese research centre Estrutura de Missão para a Extensão da Plataforma Continental (EMEPC). Researchers from Kiel University and Martin Luther University Halle-Wittenberg also contributed to the study.

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