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Shrewsbury and Telford maternity review expanded
The investigation into care at the Shrewsbury and Telford NHS Trust is the largest of its kind.
Health24.com | Extra pounds could bring more painful joints
Carrying excess pounds can be painful, literally. A new study finds that being overweight or obese ups the risk of pain in people with musculoskeletal disorders.
“Pain, osteoarthritis and weight share a complicated relationship,” said study author Dr Diana Higgins. She’s a researcher with the VA Boston Healthcare System and Boston University School of Medicine.
“Overall, the more weight a patient with a musculoskeletal disorder carries, the more likely they are to report experiencing pain, which may affect functioning and quality of life,” Higgins said in a VA news release.
Researchers analysed data on nearly two million US veterans with musculoskeletal disorders, such as non-traumatic joint disorder; arthritis; low back, back or neck pain.
Strongest in arthritis patients
Overall, 58% said they had pain. Nearly eight in 10 patients were overweight or obese. The higher a patient’s body mass index (BMI), the more likely they were to report pain. BMI is an estimate of body fat based on weight and height.
Compared to those of normal weight, those with moderate obesity (BMI of 35 to 39) were 9% more likely to report pain. And those with severe obesity (BMI of 40 or higher) were 23% more likely.
The connection between excess weight and increased risk of pain was strongest in patients with arthritis, with 40% of overweight patients and 55% of severely obese patients reporting pain.
The association between weight and pain was less pronounced in patients with back or low back pain, according to the study. The results were published recently in the journal Pain Medicine.
While the study shows a link between weight and pain in arthritis patients, further research is needed to understand this relationship, the authors said.
Strain on the joints from excess weight could lead to arthritis pain, but that relationship might also go the other way, they suggested. Pain caused by arthritis could cause patients to avoid physical activity, which could result in a higher BMI.
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Health24.com | Why so many older women develop UTIs
Many older women struggle with urinary tract infections, and researchers now think they know why.
A big reason is that their bladder walls can be invaded by several species of bacteria, a recent study found.
Urinary tract infections (UTIs) are among the most common type of bacterial infections in women, accounting for nearly 25% of all infections. UTI recurrence rates can range from 16%–36% in younger women to 55% in postmenopausal women.
Researchers at University of Texas Southwestern (UTSW) in Dallas analysed bacteria in bladder biopsies from 14 postmenopausal women with recurrent UTIs. The investigators found that in these patients, several species of bacteria can get inside the bladder’s surface area.
Diverse types of bacteria
Bacterial diversity, antibiotic resistance and immune response all play significant roles in recurrent UTIs, according to the scientists.
“Our findings represent a step in understanding [recurrent] UTIs in postmenopausal women,” senior study author Kim Orth said in a university news release. Orth is a professor of molecular biology and biochemistry at UTSW.
“We will need to use methods other than antibiotics to treat this disease, as now we observe diverse types of bacteria in the bladder wall of these patients,” Orth added.
UTI is the most common reason for antibiotic prescriptions in older adults. The high rate of UTIs has a significant social impact, and treatment costs billions of dollars a year, the study authors noted.
Recurrent UTI “reduces quality of life, places a significant burden on the healthcare system, and contributes to antimicrobial resistance,” Orth said.
Other factors believed to contribute to higher UTI rates in postmenopausal women include pelvic organ prolapse, diabetes, lack of oestrogen, loss of Lactobacilli in the vagina, and higher levels of E. coli in tissues surrounding the urethra, according to the researchers.
The report was published in the Journal of Molecular Biology.
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Coronavirus could lead to thousands more cancer deaths
Disruption to essential cancer services means treatable tumours will have been missed, experts say.
3D hand-sensing wristband signals future of wearable tech
In a potential breakthrough in wearable sensing technology, researchers from Cornell University and the University of Wisconsin, Madison, have designed a wrist-mounted device that continuously tracks the entire human hand in 3D.
The bracelet, called FingerTrak, can sense and translate into 3D the many positions of the human hand, including 20 finger joint positions, using three or four miniature, low-resolution thermal cameras that read contours on the wrist. The device could be used in sign language translation, virtual reality, mobile health, human-robot interaction and other areas, the researchers said.
“This was a major discovery by our team — that by looking at your wrist contours, the technology could reconstruct in 3D, with keen accuracy, where your fingers are,” said Cheng Zhang, assistant professor of information science and director of Cornell’s new SciFi Lab, where FingerTrak was developed. “It’s the first system to reconstruct your full hand posture based on the contours of the wrist.”
Past wrist-mounted cameras have been considered too bulky and obtrusive for everyday use, and most could reconstruct only a few discrete hand gestures.
FingerTrak’s breakthrough is a lightweight bracelet, allowing for free movement. Instead of using cameras to directly capture the position of the fingers, the focus of most prior research, FingerTrak uses a combination of thermal imaging and machine learning to virtually reconstruct the hand. The bracelet’s four miniature, thermal cameras — each about the size of a pea — snap multiple “silhouette” images to form an outline of the hand.
A deep neural network then stitches these silhouette images together and reconstructs the virtual hand in 3D. Through this method, Zhang and his fellow researchers were able to capture the entire hand pose, even when the hand is holding an object.
While the technology has a wide range of possible uses, Zhang said the most promising is its potential application in sign language translation.
“Current sign language translation technology requires the user to either wear a glove or have a camera in the environment, both of which are cumbersome,” he said. “This could really push the current technology into new areas.”
FingerTrak could also have an impact on health care applications, specifically in monitoring disorders that affect fine-motor skills, said Yin Li, assistant professor of biostatistics and medical informatics at the University of Wisconsin, Madison School of Medicine and Public Health, who contributed to the software behind FingerTrak.
“How we move our hands and fingers often tells about our health condition,” Li said. “A device like this might be used to better understand how the elderly use their hands in daily life, helping to detect early signs of diseases like Parkinson’s and Alzheimer’s.”
“FingerTrak: Continuous 3D Hand Pose Tracking by Deep Learning Hand Silhouettes Captured by Miniature Thermal Cameras on Wrist,” was published in the Proceedings of the Association for Computing Machinery on Interactive, Mobile, Wearable and Ubiquitous Technologies. It also will be presented at the 2020 ACM International Joint Conference on Pervasive and Ubiquitous Computing, taking place virtually Sept. 12-16.
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Powerful human-like hands create safer human-robotics interactions
Need a robot with a soft touch? A team of Michigan State University engineers has designed and developed a novel humanoid hand that may be able to help.
In industrial settings, robots often are used for tasks that require repetitive grasping and manipulation of objects. The end of a robot where a human hand would be found is known as an end effector or gripper.
“The novel humanoid hand design is a soft-hard hybrid flexible gripper. It can generate larger grasping force than a traditional pure soft hand, and simultaneously be more stable for accurate manipulation than other counterparts used for heavier objects,” said lead author Changyong Cao, director of the Laboratory for Soft Machines and Electronics at MSU and assistant professor in Packaging, Mechanical Engineering, and Electrical and Computer Engineering.
This new research, “Soft Humanoid Hands with Large Grasping Force Enabled by Flexible Hybrid Pneumatic Actuators,” is published in Soft Robotics.
Generally, soft-hand grippers — which are used primarily in settings where an object may be fragile, light and irregularly shaped — present several disadvantages: sharp surfaces, poor stability in grasping unbalanced loads and relatively weak grasping force for handling heavy loads.
When designing the new model, Cao and his team took into consideration a number of human-environment interactions, from fruit picking to sensitive medical care. They identified that some processes require a safe but firm interaction with fragile objects; most existing gripping systems are not suitable for these purposes.
The team explained that the design novelty resulted in a prototype demonstrating the merits of a responsive, fast, lightweight gripper capable of handling a multitude of tasks that traditionally required different types of gripping systems.
Each finger of the soft humanoid hand is constructed from a flexible hybrid pneumatic actuator — or FHPA — driven to bend by pressurized air, creating a modular framework for movement in which each digit moves independently of the others.
“Traditional rigid grippers for industrial applications are generally made of simple but re- liable rigid structures that help in generating large forces, high accuracy and repeatability,” Cao said. “The proposed soft humanoid hand has demonstrated excellent adaptability and compatibility in grasping complex-shaped and fragile objects while simultaneously maintaining a high level of stiffness for exerting strong clamping forces to lift heavy loads.”
In essence, the best of both worlds, Cao explained.
The FHPA is composed of both hard and soft components, built around a unique structural combination of actuated air bladders and a bone-like spring core.
“They combine the advantages of the deformability, adaptability and compliance of soft grippers while maintaining the large output force originated from the rigidity of the actuator,” Cao said.
He believes the prototype can be useful in industries such as fruit picking, automated packaging, medical care, rehabilitation and surgical robotics.
With ample room for future research and development, the team hopes to combine its advances with Cao’s recent work on so-called ‘smart’ grippers, integrating printed sensors in the gripping material. And by combining the hybrid gripper with ‘soft arms’ models, the researchers aim to more accurately mimic precise human actions.
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Health24.com | A drink or two a day might be good for your brain
- A study found that ‘moderate’ drinking benefited the brains of some Americans
- The benefits largely applied to white Americans
- More frequent drinking was found to reduce the brain benefits and even cause harm
Love a glass of wine with dinner? There’s good news for you from a study that finds “moderate” alcohol consumption – a glass or two per day – might actually preserve your memory and thinking skills.
This held true for both men and women, the researchers said.
There was one caveat, however: The study of nearly 20 000 Americans tracked for an average of nine years found that the brain benefit from alcohol mostly applied to whites, not African Americans. The reasons for that remain unclear, according to a team led by Changwei Li, an epidemiologist at the University of Georgia College of Public Health, in Athens.
‘Low to moderate’ drinking
Among whites, however, low to moderate drinking “was significantly associated with a consistently high cognitive function trajectory and a lower rate of cognitive decline”, compared to people who never drank, the team reported on 29 June in JAMA Network Open.
The study couldn’t prove that moderate drinking directly caused the preservation of thinking and memory, only that there was an association.
The range of drinking considered “low to moderate” in the study was set at less than eight drinks per week for women and less than 15 drinks per week for men. Drink more frequently, and any benefit to the brain begins to fade and even turn into possible harm, the researchers stressed.
Also, although the tests administered to the study participants measured cognitive attributes such as memory (word recall), overall mental status (tests of knowledge, language) and vocabulary knowledge, they were not designed to gauge whether alcohol could shield people from Alzheimer’s or other dementias.
Still, the finding that moderate drinking does no harm to thinking skills, and may even provide a benefit, “could be good news for some of the alcohol-consuming public, which makes up the majority of Americans according to the National Survey on Drug Use and Health,” said geriatric psychiatrist Dr Jeremy Koppel. He’s an associate professor at the Feinstein Institutes for Medical Research, in Manhasset, New York.
Better cognitive function
But there are always downsides to drinking, including its effects on the heart, Koppel added.
“As the study authors note, the benefits of potentially enhanced cognitive performance in alcohol-consuming middle-aged Americans must be weighed against the risks of hypertension and stroke, among other maladies, that this exposure may confer,” said Koppel, who wasn’t involved in the new study.
The research used comprehensive data from an ongoing federal government health study involving almost 20 000 people tracked for an average of nine years between 1996 and 2008. The participants averaged about 62 years of age at the beginning of the study and 60% were women.
Li’s team noted that the “findings are in line with previous research”. Those prior studies include a major study of Californians that found that moderate alcohol consumption was tied to better cognitive function among people averaging about 73 years of age. And data from the ongoing Nurses’ Health Study found that drinking that didn’t exceed more than a drink per day seemed linked to a slowing of cognitive decline for women in their 70s.
None of this means that Americans can go out and raise multiple glasses of booze to good health, however, because problem drinking is a major cause of suffering across the United States. In that regard, “public health campaigns are still needed to further reduce alcohol drinking in middle-aged or older US adults, particularly among men,” Li’s group said.
Image credit: Shutterstock
A new idea on how Earth’s outer shell first broke into tectonic plates
The activity of the solid Earth — for example, volcanoes in Java, earthquakes in Japan, etc — is well understood within the context of the ~50-year-old theory of plate tectonics. This theory posits that Earth’s outer shell (Earth’s “lithosphere”) is subdivided into plates that move relative to each other, concentrating most activity along the boundaries between plates. It may be surprising, then, that the scientific community has no firm concept on how plate tectonics got started. This month, a new answer has been put forward by Dr. Alexander Webb of the Division of Earth and Planetary Science & Laboratory for Space Research at the University of Hong Kong, in collaboration with an international team in a paper published in Nature Communications. Webb serves as corresponding author on the new work.
Dr. Webb and his team proposed that early Earth’s shell heated up, which caused expansion that generated cracks. These cracks grew and coalesced into a global network, subdividing early Earth’s shell into plates. They illustrated this idea via a series of numerical simulations, using a fracture mechanics code developed by the paper’s first author, Professor Chunan Tang of the Dalian University of Technology. Each simulation tracks the stress and deformation experienced by a thermally-expanding shell. The shells can generally withstand about 1 km of thermal expansion (Earth’s radius is ~6371 km), but additional expansion leads to fracture initiation and the rapid establishment of the global fracture network.
Although this new model is simple enough — Earth’s early shell warmed up, expanded, and cracked — superficially this model resembles long-discredited ideas and contrasts with basic physical precepts of Earth science. Before the plate tectonic revolution of the 1960’s, Earth’s activities and the distribution of oceans and continents were explained by a variety of hypotheses, including the so-called expanding Earth hypothesis. Luminaries such as Charles Darwin posited that major earthquakes, mountain-building, and the distribution of land-masses were thought to result from the expansion of the Earth. However, because Earth’s major internal heat source is radioactivity, and the continuous decay of radioactive elements means that there is less available heat as time moves forward, thermal expansion might be considered far less likely than its opposite: thermal contraction. Why, then, do Dr. Webb and his colleagues think that early Earth’s lithosphere experienced thermal expansion?
“The answer lies in consideration of major heat-loss mechanisms that could have occurred during Earth’s early periods,” said Dr. Webb. “If volcanic advection, carrying hot material from depth to the surface, was the major mode of early heat-loss, that changes everything.” Dominance of volcanism would have an unexpectedly chilling effect on the Earth’s outer shell, as documented in Dr. Webb and co-author Dr. William Moore’s earlier work (published in Nature in 2013). This is because new hot volcanic material taken from Earth’s depths would have been deposited as cold material at the surface — the heat would be lost to space. The evacuation at depth and piling up at the surface would have eventually required that the surface material sank, bringing cold material downwards. This continual downward motion of cold surface material would have had a chilling effect on the early lithosphere. Because Earth was cooling overall, the heat production and corresponding volcanism would have slowed down. Correspondingly, the downwards motion of lithosphere would have slowed with time, and thus even as the overall planet cooled, the chilled lithosphere would have been increasingly warmed via conduction from hot deep material below. This warming would have been the source of the thermal expansion invoked in the new model. The new modeling illustrates that if Earth’s solid lithosphere is sufficiently thermally expanded, it would fracture, and the rapid growth of a fracture network would divide the Earth’s lithosphere into plates.
Dr. Webb and his colleagues continue to explore the early development of our planet, and of the other planets and moons in the solar system, via integrated field-based, analytical, and theoretical studies. Their field-based explorations bring them to far-flung sites in Australia, Greenland, and South Africa; their analytical research probes the chemistry of ancient rocks and their mineral components; and their theoretical studies simulate various proposed geodynamic processes. Together, these studies chip away at one of Earth and planetary science’s greatest remaining mysteries: how and why did Earth go from a molten ball to our plate tectonic planet?
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The Azores: Exotic insect species increase on islands through human impact
Various scientific studies have warned of a global decline in the abundance and diversity of insects. These studies have been carried out mainly on the European and North American continents, with other regions, such as islands, have been less studied.
This in mind, an international research team from Portugal, France and Finland studied the insects captured over six years in the native forests of Terceira island, the Azores.
The results revealed that the diversity of exotic species of arthropods increased with time. Exotic species have been introduced into the archipelago consciously or inadvertently through economic activities.
“A greater diversity of exotic species may imply a change in various types of ecosystem services, disrupting processes such as predation and recycling of nutrients,” says Paulo Borges, researcher at the at the University of the Azores, Portugal.
In the Azores, exotic species have their maximum abundance and diversity in habitats created by man.
“The fragmentation of native habitats and the proximity of some of these non-native habitats is promoting a flow of exotic species to the native forest. The process seems to be increasing in recent years possibly due to the combination of climate change and degradation of the native forest due to the spread of invasive plants,”explains Pedro Cardoso, curator at the Finnish Museum of Natural History Luomus, University of Helsinki, Finland.
The study also shows a slight decrease in the abundance of island species that are not found anywhere else on the planet, such as the Azorean money spider (Savigniorrhipis acoreensis), which occurs on all the archipelago with the exception of Corvo island.
The study took place between 2013 and 2018. During that time, 30 thousand arthropods were captured in the native forest of Terceira. The insects collected corresponded to 159 species, 32 of which are endemic.
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