The ambulance service said the person who left the message should “remember crews are there to save lives”.
Category Archives: Mind Building
Severe allergic reactions rise in children in England over past five years
The parents of Natasha Ednan-Laperouse, who died in 2016, call the increase “deeply alarming”.
NASA’s Mars 2020 will hunt for microscopic fossils
Scientists with NASA’s Mars 2020 rover have discovered what may be one of the best places to look for signs of ancient life in Jezero Crater, where the rover will land on Feb. 18, 2021.
A paper published in the journal Icarus identifies distinct deposits of minerals called carbonates along the inner rim of Jezero, the site of a lake more than 3.5 billion years ago. On Earth, carbonates help form structures that are hardy enough to survive in fossil form for billions of years, including seashells, coral and some stromatolites — rocks formed on this planet by ancient microbial life along ancient shorelines, where sunlight and water were plentiful.
The possibility of stromatolite-like structures existing on Mars is why the concentration of carbonates tracing Jezero’s shoreline like a bathtub ring makes the area a prime scientific hunting ground.
Mars 2020 is NASA’s next-generation mission with a focus on astrobiology, or the study of life throughout the universe. Equipped with a new suite of scientific instruments, it aims to build on the discoveries of NASA’s Curiosity, which found that parts of Mars could have supported microbial life billions of years ago. Mars 2020 will search for actual signs of past microbial life, taking rock core samples that will be deposited in metal tubes on the Martian surface. Future missions could return these samples to Earth for deeper study.
In addition to preserving signs of ancient life, carbonates can teach us more about how Mars transitioned from having liquid water and a thicker atmosphere to being the freezing desert it is today. Carbonate minerals formed from interactions between carbon dioxide and water, recording subtle changes in these interactions over time. In that sense, they act as time capsules that scientists can study to learn when — and how — the Red Planet began drying out.
Measuring 28 miles (45 kilometers) wide, Jezero Crater was also once home to an ancient river delta. The “arms” of this delta can be seen reaching across the crater floor in images taken from space by satellite missions like NASA’s Mars Reconnaissance Orbiter. The orbiter’s Compact Reconnaissance Imaging Spectrometer for Mars instrument, or CRISM, helped produce colorful mineral maps of the “bathtub ring” detailed in the new paper.
Scientists from NASA’s Mars 2020 mission and the European Space Agency-Roscosmos ExoMars mission are in the Australian Outback to hone research techniques before their missions launch to the Red Planet in summer 2020. They are hoping to better understand how to search for signs of ancient life on Mars. The Pilbara region of North West Australia is home to “stromatolites,” the oldest confirmed fossilized lifeforms on Earth.
“CRISM spotted carbonates here years ago, but we only recently noticed how concentrated they are right where a lakeshore would be,” said the paper’s lead author, Briony Horgan of Purdue University in West Lafayette, Indiana. “We’re going to encounter carbonate deposits in many locations throughout the mission, but the bathtub ring will be one of the most exciting places to visit.”
It isn’t guaranteed that the shoreline carbonates were formed in the lake; they could have been deposited before the lake was present. But their identification makes the site’s western rim, called “the marginal carbonate-bearing region,” one of the richest troves of these minerals anywhere in the crater.
The Mars 2020 team expects to explore both the crater floor and delta during the rover’s two-year prime mission. Horgan said the team hopes to reach the crater’s rim and its carbonates near the end of that period.
“The possibility that the ‘marginal carbonates’ formed in the lake environment was one of the most exciting features that led us to our Jezero landing site. Carbonate chemistry on an ancient lakeshore is a fantastic recipe for preserving records of ancient life and climate,” said Mars 2020 Deputy Project Scientist Ken Williford of NASA’s Jet Propulsion Laboratory in Pasadena, California. JPL leads the 2020 mission. “We’re eager to get to the surface and discover how these carbonates formed.”
Jezero’s former lake shoreline isn’t the only place scientists are excited to visit. A new study in Geophysical Research Letters points to a rich deposit of hydrated silica on the edge of the ancient river delta. Like carbonates, this mineral excels at preserving signs of ancient life. If this location proves to be the bottom layer of the delta, it will be an especially good place to look for buried microbial fossils.
The Mars 2020 rover will launch in July or August 2020 from Cape Canaveral, Florida. The Mars 2020 Project at JPL manages rover development for the Science Mission Directorate at NASA Headquarters in Washington. NASA’s Launch Services Program, based at the agency’s Kennedy Space Center in Florida, is responsible for launch management.
Mars 2020 is part of a larger program that includes missions to the Moon as a way to prepare for human exploration of the Red Planet. Charged with returning astronauts to the Moon by 2024, NASA will establish a sustained human presence on and around the Moon by 2028 through NASA’s Artemis lunar exploration plans.
The Johns Hopkins University Applied Physics Laboratory in Laurel, Maryland, leads MRO’s CRISM investigation.
For more information about Mars 2020, go to:
Health24.com | No need for alarm over newly identified HIV strain
It’s a headline you don’t want to read, but experts say it’s actually good news. Researchers from the University of Missouri, Presbyterian Mission Agency, and healthcare company Abbott last week confirmed the discovery of a new subtype of the human immunodeficiency virus (HIV).
The new strain was classified as HIV-1 Group M, subtype L. The results of their research were published in the Journal of Acquired Immune Deficiency syndromes (Jaids).
This breakthrough can be traced to the Democratic Republic of Congo, and the strain is a subtype of a known existing group. Samples of the newly identified strain of the virus were collected in the 1980s, 1990s and then again in 2001.
However, in order for a new subtype to be declared, three separate cases of the strain need to be discovered independently.
Because of the limited technology at the time, sequencing the third sample was difficult to do, which meant that the frozen blood sample had to be kept on ice since 2001 – which is why it’s being labelled a newly-identified strain, and not a new strain.
No need to panic
HIV has two types: HIV-1 and HIV-2. There are hundreds of subtypes, and they are designated alphabetically. Group M is a strain of HIV-1. New subtypes are being discovered all the time, and the discovery of subtype L is not something to be alarmed about, say experts.
As a matter of fact, the discovery may be helpful in staying ahead in the fight against the virus.
“By advancing our techniques and using next-generation sequencing technology, we are pulling the needle out with a magnet,” Dr Mary Rogers, one of the authors of the study said.
“This scientific discovery can help us ensure we are stopping new pandemics in their tracks.”
How close are we to a cure?
Only a small number of people are infected with the newly identified strain, and current treatment will remain effective against it. In future, however, people who test for HIV will need to be tested for the newly-discovered strain as well.
According to UNAIDS Global HIV & AIDS statistics – 2019 fact sheet, 37.9 million people globally are living with HIV, and 74.9 million people have become infected with HIV since the start of the epidemic.
Although there have been many advancements in the field of HIV/Aids, there’s no cure as yet. Existing drugs aim to decrease the risk of transmission of the virus, and those have been very effective.
According to the Centers for Disease Control and Prevention: “Studies have shown that PrEP reduces the risk of getting HIV from sex by about 99% when taken daily. Among people who inject drugs, PrEP reduces the risk of getting HIV by at least 74% when taken daily.”
There are also vaccines that are being trialled around the world, with results said to be expected around 2023.
Discoveries like the latest one will hopefully help to end the HIV pandemic, said Carole McArthur one of the authors of the study: “We must continue to out-think this continuously changing virus and use the latest advancements in technology and resources to monitor its evolution.”
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Hospital waiting times at worst-ever level
Record numbers in England are on hospital waiting lists, while A&E delays highest since target introduced.
Health24.com | OPINION: World Diabetes Day – ‘Obesity is the main driver of South Africa’s type 2 diabetes epidemic’
Diabetes mellitus exists in two distinct forms: type 1, which usually occurs in younger people who require insulin injections from the time of diagnosis, and type 2, which usually occurs in older, overweight people who start treatment on lifestyle modifications and tablets.
Type 2 diabetes is a progressive disease, and after five years as many as 50% of people living with type 2 diabetes may require insulin injections to control their blood glucose levels.
High obesity levels in SA
Obesity is the main driver of the current type 2 diabetes epidemic. People living with diabetes also frequently have high blood pressure and high cholesterol levels that require treatment.
In South Africa, diabetes is of particular concern. South Africa has the highest prevalence of overweight or obese citizens in Sub-Saharan Africa. Indeed, close to four out of 10 men and seven out of 10 women are either overweight or obese.
The prevalence of type 2 diabetes varies depending on age and ethnic group. This ranges from 7% of the population to as high as 25% in some communities. South Africans of Indian descent are particularly at risk.
Alarmingly, the International Diabetes Federation predicts that between the years 2000 and 2030 there will be a 261% increase in diabetes in Sub-Saharan Africa. Worldwide, more people die from diabetes than from tuberculosis (TB), HIV and malaria put together. In 2016, Statistics South Africa revealed that diabetes was second only to TB as a natural cause of death.
The majority of people living with diabetes receive treatment in the public sector primary care environment. Early in the disease, treatment consisting of lifestyle modifications and oral medication is straightforward and done according to acceptable guidelines and algorithms.
However, over time, management becomes more complex and complications such as foot ulcers and amputations, renal disease including renal failure, eye disease including blindness and stroke and heart attacks may occur. This complexity demands care that is often not available or suboptimal, most often due to resource constraints such as medical personnel and equipment.
Early detection and treatment
In response to these challenges in diabetes management in the primary care sector, which affect thousands of South Africans, the Department of Internal Medicine at the University of Pretoria is leading a multidisciplinary team of physicians, nutritionists, sport scientists, nurses and public health experts in finding innovative and evidence-based ways to improve care for people living with diabetes.
The team interacting with the clinics consists of a project leader, a nurse coordinator, nurses and clinical associates. The Tshwane Insulin Project (TIP) is a translational research programme funded over five years by the Lilly Global Health initiative. This project aims to improve early detection and treatment of diabetes at primary care in the Tshwane district, which includes approximately 68 health facilities (primary care clinics and community health centres).
Of particular significance is the focus on addressing the challenges of safely initiating and titrating insulin in diabetes patients at primary care level should they require it. The goal is to design, implement and evaluate a nurse-led, community worker-assisted and patient-centred innovative model of care that will facilitate insulin use in primary care.
Nationally, many clinics do not have doctors available on site, and the TIP study will evaluate the use of a mobile app to facilitate communication between healthcare workers (nurses and community health workers) with a designated primary care physician.
This novel approach has significant operational as well as economic benefits in the delivery of care. Patients are started on insulin and the dose is adjusted weekly as required. A unique feature of the TIP strategy is the implementation of home-based visits. The patient is visited at home by a trained community health care worker and a team leader who is a registered nurse.
This ensures treatment compliance as well as safety of the people who are injecting insulin and testing their blood glucose with glucose meters provided to them by the project. During the home visits, patients receive personalised education sessions around diabetes and living with insulin. Through those education sessions, they are empowered and equipped to better take care of their diabetes and take control of their disease.
Complete spectrum of care
Initial baseline surveys with healthcare workers and patients were conducted during 2019 to evaluate the barriers and opportunities regarding insulin use in primary care. These highlighted the desire of nurses to be empowered to use insulin, the challenge of time dedicated to diabetes education, other clinical tasks and unavailability of glucose meters and glucose strips, as well as the fear of injections and reluctance to start insulin by the patients.
Through training interventions facilitated by the TIP experts, we work with the Department of Health and City of Tshwane to empower primary care nurses and doctors to improve the complete spectrum of care for people living with diabetes. These efforts are an important long-term investment which will lead to improved disease control as well as earlier detection and management of complications.
In 2020, the TIP study will expand with a bold aim, which is to initiate at least 400 people on insulin all around the Tshwane District and improve their quality of life as they bravely live flourishing lives despite having diabetes.
TIP is an embodiment of the ethos of the University of Pretoria as passionate and dedicated UP staff members implement innovative ground-breaking research which has the potential to positively impact the lives of thousands of South Africans living with diabetes.
Professor Paul Rheeder is a Senior Lecturer in the University of Pretoria’s Department of Internal Medicine based at Pretoria’s Steve Biko Academic Hospital.
Disclaimer: Health24 encourages freedom of speech and the expression of diverse views. The views of columnists published on Health24 are therefore their own and do not necessarily represent the views of Health24.
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Future rainfall could far outweigh current climate predictions in UK
Homes and communities across the UK have felt the full force of torrential downpours in recent weeks. And the UK’s uplands could in future see significantly more annual rainfall than is currently being predicted in national climate models, according to new research by the University of Plymouth, UK.
Scientists analysed rainfall records from the 1870s to the present day and compared them against those featured in the Met Office’s UK Climate Projections 2018 (UKCP18) report.
Their findings show that there has been a significant increase in spring, autumn and winter precipitation, greatest in upland windward areas of the region, with winter increases broadly consistent with UKCP18 projections.
However, their results show for spring, summer and autumn precipitation there could be large divergence by the mid to late 21st century, with the observed mismatch greatest in upland areas.
The study, published in Climate Research, was conducted by research student Thomas Murphy and academics from the University’s School of Geography, Earth and Environmental Science and School of Biological and Marine Sciences.
Dr Paul Lunt, Associate Professor in Environmental Science and one of the study’s authors, said: “Our study helps to contextualise the latest UK climate change projections, and suggest caution is required when making assumptions on climate impacts based on climate models. Current models predict that by 2050, summer rainfall on Dartmoor will fall by as much as 20%, but our results from past records show that in the uplands it is on an upward trajectory.
“This study shows there have been significant increases in spring, autumn, winter and annual precipitation for upland regions in South West England between 1879 and 2012. Meanwhile the moderate increases in summer precipitation represent a deviation from the drier summers predicted within current and previous climate models.
“In that regard, this research highlights the complex challenges facing those trying to predict the effects of climate change. Upland areas are among the most important UK regions in terms of biodiversity and carbon sequestration, but they are also the most vulnerable to increased precipitation.”
Upland areas more than 300m above sea level cover around one third of the UKs land area and are considered of national and international importance due to their biodiversity and cultural heritage. They are also the source of 68 per cent of the UK’s freshwater and have a significant role in flood risk mitigation.
Levels of precipitation in the uplands are typically twice the average of those for UK lowland sites. As a result, there contribution to flood risk and downstream flood damage is disproportion to their catchment area.
The research focused on Dartmoor and Plymouth, aiming to scrutinise one of the longest running upland and lowland precipitation records anywhere in Western Europe. It also looked at shorter-term records from a number of upland sites.
The results show that over the past 130 years rainfall in upland areas has increased in all seasons, with spring, autumn and winter increasing by more than 12%. In Plymouth, rainfall has increased by more than 5% in all seasons apart from summer, where there has been slight decrease. Annual levels in the uplands and Plymouth have risen by 11% (226mm) and 5% (46mm) respectively over the same period.
The researchers also say that while these results are important at a local scale, they are also relevant for upland coastal sites across the North East Atlantic.
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‘Are we alone?’ Study refines which exoplanets are potentially habitable
In order to search for life in outer space, astronomers first need to know where to look. A new Northwestern University study will help astronomers narrow down the search.
The research team is the first to combine 3D climate modeling with atmospheric chemistry to explore the habitability of planets around M dwarf stars, which comprise about 70% of the total galactic population. Using this tool, the researchers have redefined the conditions that make a planet habitable by taking the star’s radiation and the planet’s rotation rate into account.
Among its findings, the Northwestern team, in collaboration with researchers at the University of Colorado Boulder, NASA’s Virtual Planet Laboratory and the Massachusetts Institute of Technology, discovered that only planets orbiting active stars — those that emit a lot of ultraviolet (UV) radiation — lose significant water to vaporization. Planets around inactive, or quiet, stars are more likely to maintain life-sustaining liquid water.
The researchers also found that planets with thin ozone layers, which have otherwise habitable surface temperatures, receive dangerous levels of UV dosages, making them hazardous for complex surface life.
“For most of human history, the question of whether or not life exists elsewhere has belonged only within the philosophical realm,” said Northwestern’s Howard Chen, the study’s first author. “It’s only in recent years that we have had the modeling tools and observational technology to address this question.”
“Still, there are a lot of stars and planets out there, which means there are a lot of targets,” added Daniel Horton, senior author of the study. “Our study can help limit the number of places we have to point our telescopes.”
The research will be published online Nov. 14 in the Astrophysical Journal.
Horton is an assistant professor of Earth and planetary sciences in Northwestern’s Weinberg College of Arts and Sciences. Chen is a Ph.D. candidate in Northwestern’s Climate Change Research Group and a NASA future investigator.
The ‘Goldilocks zone’
To sustain complex life, planets need to be able to maintain liquid water. If a planet is too close to its star, then water will vaporize completely. If a planet is too far from its star, then water will freeze, and the greenhouse effect will be unable to keep the surface warm enough for life. This Goldilocks area is called the “circumstellar habitable zone,” a term coined by Professor James Kasting of Penn State University.
Researchers have been working to figure out how close is too close — and how far is too far — for a planet to sustain liquid water. In other words, they are looking for the habitable zone’s “inner edge.”
“The inner edge of our solar system is between Venus and Earth,” Chen explained. “Venus is not habitable; Earth is.”
Horton and Chen are looking beyond our solar system to pinpoint the habitable zones within M dwarf stellar systems. Because they are numerous and easier to find and investigate, M dwarf planets have emerged as frontrunners in the search for habitable planets. They get their name from the small, cool, dim stars around which they orbit, called M dwarfs or “red dwarfs.”
Crucial chemistry
Other researchers have characterized the atmospheres of M dwarf planets by using both 1D and 3D global climate models. These models also are used on Earth to better understand climate and climate change. Previous 3D studies of rocky exoplanets, however, have missed something important: chemistry.
By coupling 3D climate modeling with photochemistry and atmospheric chemistry, Horton and Chen constructed a more complete picture of how a star’s UV radiation interacts with gases, including water vapor and ozone, in the planet’s atmosphere.
In their simulations, Horton and Chen found that a star’s radiation plays a deciding factor in whether or not a planet is habitable. Specifically, they discovered that planets orbiting active stars are vulnerable to losing significant amounts of water due to vaporization. This stands in stark contrast to previous research using climate models without active photochemistry.
The team also found that many planets in the circumstellar habitable zone could not sustain life due to their thin ozone layers. Despite having otherwise habitable surface temperatures, these planets’ ozone layers allow too much UV radiation to pass through and penetrate to the ground. The level of radiation would be hazardous for surface life.
“3D photochemistry plays a huge role because it provides heating or cooling, which can affect the thermodynamics and perhaps the atmospheric composition of a planetary system,” Chen said. “These kinds of models have not really been used at all in the exoplanet literature studying rocky planets because they are so computationally expensive. Other photochemical models studying much larger planets, such as gas giants and hot Jupiters, already show that one cannot neglect chemistry when investigating climate.”
“It has also been difficult to adapt these models because they were originally designed for Earth-based conditions,” Horton said. “To modify the boundary conditions and still have the models run successfully has been challenging.”
‘Are we alone?’
Horton and Chen believe this information will help observational astronomers in the hunt for life elsewhere. Instruments, such as the Hubble Space Telescope and James Webb Space Telescope, have the capability to detect water vapor and ozone on exoplanets. They just need to know where to look.
“‘Are we alone?’ is one of the biggest unanswered questions,” Chen said. “If we can predict which planets are most likely to host life, then we might get that much closer to answering it within our lifetimes.”
Horton and Chen are both members of CIERA (Center for Interdisciplinary and Exploratory Research in Astrophysics).
The study was supported by the Future Investigators in NASA Earth and Space Science and Technology graduate research award (80NSSC19K1523) and a NASA Habitable Worlds grant (80NSSC17K0257). Computational work was completed at Northwestern’s QUEST high-performance computing facility.
Health24.com | High-tech pacifier might monitor baby’s blood sugar
Parents of babies with type 1 diabetes have to prick their child’s skin multiple times a day to check their blood sugar. But researchers may have developed a much easier way to check – a sugar-sensing pacifier.
While baby sucks on the pacifier, it collects saliva, tests the sugar (glucose) levels and wirelessly sends results to a receiver that a parent/caregiver can see.
Few small parts
In a proof-of-concept study, researchers had adults with type 1 diabetes use the pacifier before and after a meal. Initial tests showed that the device can, in fact, measure changes in saliva sugar levels that corresponded to changes in blood sugar levels.
“We modified the pacifier as little as possible so that the baby could not tell the difference from a common one and reject it,” said study co-author Juliane Sempionatto, a doctoral candidate at the University of California, San Diego.
The researchers also designed the pacifier with as few small parts as possible, and positioned the sugar-sensing technology on the outside to keep it as far away from the baby’s mouth as possible. As the baby sucks on the pacifier, saliva is pumped into a collecting channel.
The technology is similar to standard blood sugar meters.
“The device gave us good correlation with the blood glucose when tested in adults. We were able to tell when their blood glucose was high with great accuracy,” Sempionatto said.
Current blood sugar levels are one of the factors that helps decide how much insulin a diabetic needs.
Challenges remain
Insulin is a hormone that helps usher the sugar from foods into the body’s cells to be used as fuel. Without enough insulin, the sugar stays in the blood, where it can cause short- and long-term damage. Getting the right amount of insulin is crucial – too much or too little can cause problems.
Despite encouraging trial results, challenges remain in bringing the patented pacifier device to market.
One is concern about the small parts that make up the device. Sempionatto said these all have to be contained into a single piece to ensure that the device isn’t a choking hazard.
Another concern is that babies may have food residue in their mouths. That’s one of the main reasons why the device was tested in adults.
“We could ask the adult volunteers to brush their teeth and then collect some amount of saliva in the sensor. With babies, it’s completely different,” Sempionatto said, adding that babies often spit up, and milk residue in their mouths could interfere with the way the device works.
In spite of those challenges, however, researchers are hopeful about this type of device. Besides helping check sugar levels in babies with diabetes, the device might also be helpful in detecting low sugar levels in children with other conditions. Sempionatto said the technology might also be used one day for detecting infections.
Non-invasive option
Sanjoy Dutta, vice president of research at JDRF (formerly the Juvenile Diabetes Research Foundation), said the new research was “very innovative”.
Dutta said, “We’re keen on alternative technologies, and on people having choices for managing their diabetes,” adding that JDRF had funded a number of alternative blood sugar testing technologies. He said he’s seen testing through tears, breath, saliva and even a tattoo, but so far nothing has proved as accurate as blood sugar monitoring.
And, Dutta said, continuous glucose monitoring – tiny sensors inserted underneath the skin that provide blood sugar readings every few minutes – “has set the bar higher”.
Sempionatto acknowledged that continuous glucose monitors are “desirable” for people with type 1 diabetes. But the idea of the pacifier is to have a “truly non-invasive option” for measuring babies’ sugar, she said.
“Even the smallest sensor, needle or device is too big for a newborn, and anything can hurt them,” Sempionatto said. “The pacifier has the advantage that it does not need to be placed on the baby’s body.”
The findings were recently published in Analytical Chemistry, a journal of the American Chemistry Society.
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Complementary cancer therapies ‘do more harm than good’
Garlic and ginger pills can delay the healing of skin wounds when breast cancer spreads, expert says.






