Health24.com | How the after-effects of measles could be even more serious than previously thought

The number of vaccine-hesitant people seems to be on the rise, and the debate between people who vaccinate and those who refuse to do so is growing more intense by the day.

Over the last few years, an increasing number of measles outbreaks worldwide have been ascribed to the growing number of “anti-vaxxers”.

Measles is often regarded as a harmless childhood disease, but a new study suggests that the effect of the disease on children’s immune systems is much more serious than previously suspected.

What exactly is meant by by ‘immune amnesia’?

According to the research teams, measles causes something called “immune amnesia”, which means that the virus destroys existing defences against pathogens that the body previously encountered. This means that the body becomes vulnerable to many infections.

Stephen Elledge, professor of genetics and medicine and Harvard Medical School, stated that the evidence that measles destroys the immune system is really strong, making it extremely important to get vaccinated against the disease. 

A news report stated that an analysis of blood from 77 unvaccinated children before and after measles revealed that the virus erased immunity against previous pathogens. Measles eliminated between 11% and 73% of protective antibodies that were built up during previous encounters with viruses.

This research was published 31 October 2019 in the journal Science.

Not just an innocent children’s illness

According to Elledge, measles, apart from being one of the most contagious viruses around. is a lot more harmful than ever suspected,

The measles virus is so contagious that, before the development of he first vaccine in 1963, it affected between three million and four million people per year in the United States alone.

Especially in the poorer parts of South Africa, measles used to take a high toll on children, but vaccination campaigns soon got the problem under control.  

As more and more people were vaccinated, the number of cases of measles plummeted worldwide, but with the growing resistance against vaccination, the disease is on the increase again. 

Serious birth complications

Besides destroying the existing immune system, there are a number of serious complications that can result from measles such as croup; pneumonia; damage to the eyes; seizures caused by high fever; and inflammation of the brain (encephalitis).

Encephalitis is very rare, but the risk increases as children grow older. It can be fatal and can appear weeks or even months after a bout of measles, especially in immune-compromised people.

When measles leaves the immune system compromised, people in developing countries like South Africa are more susceptible to other highly contagious communicable diseases such as tuberculosis.

And when pregnant women contract measles, it can lead to serious birth complications, and even miscarriage and stillbirth.

Vaccination – the only solution

The only recourse against measles is the vaccine known as MMR. Routine measles vaccination is given at nine and 15 months in South Africa. The vaccination at 15 months is given as a combined measles, mumps and rubella (MMR) vaccine, and a booster shot helps to give long-term immunity.

Dr Charlie Weller, Head of Vaccines at Wellcome, stated in a news report: “Measles is highly contagious and its potentially devastating consequences are well known. This study finds that measles also has the potential to weaken our body’s existing immune response to other diseases, leaving us vulnerable to infections.

“These findings further strengthen the vital role the MMR vaccine plays in public health and protecting us from deadly disease. It is yet another reminder of how important vaccines are as a vital resource in eliminating infectious disease.”

Elledge has one message he wants people to take away from the latest research: “Vaccinate your kids. Children who skip the measles vaccine and become infected may actually need to be revaccinated against previous diseases.”

Image credit: iStock

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Hummus recall extended over salmonella scare

Dips stocked by retailers such as Asda, Morrisons and Sainsbury’s have been affected by the recall.

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NHS Scotland given extra £10m to ease winter pressures

The Scottish government says the cash will ease pressure on the health service in the coming months.

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Dietary fiber effectively purifies carbon nanotubes

A new, cheaper method easily and effectively separates two types of carbon nanotubes. The process, developed by Nagoya University researchers in Japan, could be up-scaled for manufacturing purified batches of single-wall carbon nanotubes that can be used in high-performance electronic devices. The findings were published in the journal Applied Physics Express.

Single-wall carbon nanotubes (SWCNTs) have excellent electronic and mechanical properties, making them ideal candidates for use in a wide range of electronic devices, including the thin-film transistors found in LCD displays. A problem is that only two-thirds of manufactured SWCNTs are suitable for use in electronic devices. The useful semiconducting SWCNTs must be separated from the unwanted metallic ones. But the most powerful purification process, known as aqueous two-phase extraction, currently involves the use of a costly polysaccharide, called dextran.

Organic chemist Haruka Omachi and colleagues at Nagoya University hypothesized that dextran’s effectiveness in separating semiconducting from metallic SWCNTs lies in the linkages connecting its glucose units. Instead of using dextran to separate the two types of SWCNTs, the team tried the significantly cheaper isomaltodextran, which has many more of these linkages.

A batch of SWCNTs was left for 15 minutes in a solution containing polyethylene glycol and isomaltodextrin and then centrifuged for five minutes. Three different types of isomaltodextrin were tried, each with a different number of linkages and a different molecular weight. The team found that metallic SWCNTs separated to the bottom isomaltodextrin part of the solution, while the semiconducting SWCNTs floated to the top polyethylene glycol part.

The type of isomaltodextrin with high molecular weight and the most linkages was the most (99%) effective in separating the two types of SWCNTs. The team also found that another polysaccharide, called pullulan, whose glucose units are connected with different kinds of linkages, was ineffective in separating the two types of SWCNTs. The researchers suggest that the number and type of linkages present in isomaltodextrin play an important role in their ability to effectively separate the carbon nanotubes.

The team also found that a thin-film transistor made with their purified semiconducting SWCNTs performed very well.

Isomaltodextrin is a cheap and widely available polysaccharide produced from starch that is used as a dietary fibre. This makes it a cost-effective alternative for the SWCNT extraction process. Omachi and his colleagues are currently in discussions with companies to commercialize their approach. They are also working on improving the performance of thin-film transistors using semiconducting SWCNTs in flexible displays and sensor devices.

Story Source:

Materials provided by Nagoya University. Note: Content may be edited for style and length.

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Simple blood test for early detection of breast cancer

Breast cancer could be detected up to five years before there are any clinical signs of it, using a blood test that identifies the body’s immune response to substances produced by tumour cells, according to new research presented at the 2019 NCRI Cancer Conference today (Sunday).

Cancer cells produce proteins called antigens that trigger the body to make antibodies against them — autoantibodies. Researchers at the University of Nottingham (UK) have found that these tumour-associated antigens (TAAs) are good indicators of cancer, and now they have developed panels of TAAs that are known already to be associated with breast cancer to detect whether or not there are autoantibodies against them in blood samples taken from patients.

In a pilot study the researchers, who are part of the Centre of Excellence for Autoimmunity in Cancer (CEAC) group at the School of Medicine, University of Nottingham, took blood samples from 90 breast cancer patients at the time they were diagnosed with breast cancer and matched them with samples taken from 90 patients without breast cancer (the control group).

They used screening technology (protein microarray) that allowed them to screen the blood samples rapidly for the presence of autoantibodies against 40 TAAs associated with breast cancer, and also 27 TAAs that were not known to be linked with the disease.

Presenting the research at the NCRI Conference, Ms Daniyah Alfattani, a PhD student in the group, said: “The results of our study showed that breast cancer does induce autoantibodies against panels of specific tumour-associated antigens. We were able to detect cancer with reasonable accuracy by identifying these autoantibodies in the blood.”

The researchers identified three panels of TAAs against which to test for autoantibodies. The accuracy of the test improved in the panels that contained more TAAs. The panel of five TAAs correctly detected breast cancer in 29% of the samples from the cancer patients and correctly identified 84% of the control samples as being cancer-free. The panel of seven TAAs correctly identified cancer in 35% of cancer samples and no cancer in 79% of control samples. The panel of nine antigens correctly identified cancer in 37% of cancer samples and no cancer in 79% of the controls.

“We need to develop and further validate this test,” said Ms Alfattani. “However, these results are encouraging and indicate that it’s possible to detect a signal for early breast cancer. Once we have improved the accuracy of the test, then it opens the possibility of using a simple blood test to improve early detection of the disease.”

The researchers are now testing samples from 800 patients against a panel of nine TAAs, and they expect the accuracy of the test to improve with these larger numbers.

“A blood test for early breast cancer detection would be cost effective, which would be of particular value in low and middle income countries. It would also be an easier screening method to implement compared to current methods, such as mammography,” said Ms Alfattani.

The researchers estimate that, with a fully-funded development programme, the test might become available in the clinic in about four to five years.

A similar test for lung cancer is currently being tested in a randomised controlled trial in Scotland, involving 12,000 people at high risk of developing lung cancer because they smoke. They have been randomised to have (or not) an autoantibody blood test called ELISA (Early CDT-Lung). Participants who test positive for the autoantibodies are then followed up with a CT scan every two years in order to detect lung cancer in its early stages when it is easier to treat.

The CEAC group is also working on similar tests for pancreatic, colorectal and liver cancers. Solid tumours like these, as well as lung and breast cancer, represent around 70% of all cancers.

“A blood test capable of detecting any of these cancers at an early stage is the over-riding objective of our work,” concluded Ms Alfattani.

Dr Iain Frame, CEO of NCRI said: “Early diagnosis using simple, non-invasive ways of detecting the first signs of cancer is a key strategic priority for NCRI and something we’d all like to see working in practice. The results from this pilot study for a blood test to detect early breast cancer are promising and build on this research group’s expertise in other cancers, such as lung cancer. It’s obviously early days but we look forward to seeing the results from the larger group of patients that are now being investigated.”

Abstract no: Poster 2966, poster board number 37, area 2. “Clinical utility of autoantibodies in early detection of breast cancer,” by Daniyah Alfattani et al. 19.20 hrs GMT. Silent theatre 2, Exhibition Hall, Sunday 3 November.

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Health24.com | Too little time to exercise? Survey suggests otherwise

“I’d love to exercise more, but I just can’t find the time.”

It’s a common refrain from many but, for most, it might also be untrue, a new survey finds.

Inactive free time

Researchers at the non-profit RAND Corporation polled more than 32 000 Americans over the age of 14.

The survey found that, generally, people have an average of more than five hours of leisure time per day. Men typically had more spare time than women.

On the other hand, not even 7% of that free time was spent doing physical activity, the survey found.

Instead, people appeared to spend most of their free time watching television or using their smartphones or other devices, the findings showed.

The study challenges the notion that “a lack of leisure time is a major reason that Americans do not get enough physical activity,” study co-author Dr Deborah Cohen, a physician researcher at RAND, said in a corporate news release.

“We found no evidence for those beliefs,” she said.

Class makes a difference

For the study, which was conducted between 2014 and 2016, Cohen’s team didn’t include in their free-time calculations activities such as self-care, household activities and family caretaking – things like grooming, shopping and playing with children.

And even with those chores out of the picture, the survey found that, regardless of race/ethnicity or age, no group had less than 4.5 hours of free time per day.

Men typically had over 30 minutes more free time a day than women, according to the study published recently in the journal Preventing Chronic Disease.

Still, regardless of gender, very little leisure time was spent exercising. Men spent an average of 6.6% of their free time on physical activity, compared with 5% for women.

Class seemed to make a slight difference: More affluent men and women spent more of their free time on physical activity and less on screen time, compared to those with lower incomes, the study found.

Fewer hours spent active can take its toll on health. The researchers estimated that low levels of physical activity may account for 8% of deaths in the United States each year.

Get the blood flowing

Dr Sharon Zarabi, an expert in exercise and weight control, wasn’t surprised by the findings. She said, “We all have 24 hours in the day, and how you choose to use it says a lot about what you value.”

Putting a renewed focus on health means finding creative ways to work more activity into your day, said Zarabi, who directs the bariatric programme at Lenox Hill Hospital, in New York City.

That could mean “taking the stairs more often, getting off a train stop ahead, or parking a distance from your destination,” she noted.

And if you love watching TV or scanning your smartphone, “check your e-mails while cycling on the bike,” Zarabi suggested. Or “devise a 10-minute workout routine in the morning including push-ups, squats, sit-ups, planks – anything that gets the blood flowing.”

That could be a challenge for millions of Americans, however. According to the latest US National Health Interview Survey, only about half get the recommended 150 minutes a week of moderate or vigorous activity.

Image credit: iStock

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Health24.com | The 10 healthiest (and least healthy) cooking oils, according to nutritionists

Now that the low-fat life is a thing of the past, you’ve probably considered pouring olive oil over your entire life.

Really, though, with about a thousand different types of cooking oils seemingly deemed a-okay now, it’s tricky to tell which are actually healthy — and which to use for different recipes and cooking methods.

Two key factors to keep in mind: saturated fat content and smoke point.

Though the keto diet has made butter and coconut oil (both of which are high in saturated fat) crazy-popular, the USDA Dietary Guidelines for Americans still recommends limiting saturated fat to less than 10 percent of your daily calories, choosing oils higher in unsaturated fat instead.

Plus, the right smoke point (the temp at which an oil starts burning and breaking down) is also crucial — especially when you’re cooking at high heat, like searing a steak.

Here, dietitians break down seven of the healthiest cooking oils in the game (and three questionable ones), so you can keep your pantry as healthy — and your cooking adventures as catastrophe-free — as possible.

1. Avocado Oil

“This is one of our favourite cooking oils,” say Lyssie Lakatos, and Tammy Lakatos Shames, co-owners of The Nutrition Twins. “The flavour isn’t very strong, so it doesn’t overpower the foods cooked with it.”

Avocado oil contains vitamin E, a fat-soluble vitamin that works as an antioxidant to protect cells from damage.

Plus, since avocado oil is high in healthy unsaturated fats, specifically monounsaturated fats, it’s not only good for you, but also has a higher smoke point than oils rich in polyunsaturated fats.

Latakos and Latakos Shames recommend using this one for high-heat cooking methods, like stir-frying, sautéing, and searing.

Nutrition per tablespoon: 124 calories, 14 g fat (1.6 g saturated, 9.9 g monounsaturated, 1.9 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

2. Hazelnut Oil

Although you probably don’t want to use hazelnut oil to cook potatoes or sear meat, its sweet aroma makes it a fun option for fall vegetables like winter squash, carrots, and parsnips.

Thanks to lots of monounsaturated fats, hazelnut oil has a high smoke point and lends itself well to high oven temperatures. Like avocado oil, hazelnut oil also provides the added bonus of some vitamin E.

Nutrition per tablespoon: 120 calories, 13.6 g fat (1 g saturated, 10.6 g monounsaturated, 1.4 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

3. Extra-virgin Olive Oil (EVOO)

High in antioxidants and monounsaturated fats, extra-virgin olive oil is one of the healthiest oils you can cook with Lakatos says.

“Even though it doesn’t have the highest smoke point, its antioxidants resist oxidation,” she says. The result: You reap more of their benefits.

Lakatos recommends using EVOO for roasting or stewing. (Skip it for higher-heat cooking, like pan-frying.)

Nutrition per tablespoon: 120 calories, 14 g fat (2 g saturated, 10 g monounsaturated, 2 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

4. Regular Olive Oil

Olive oil not labelled “extra-virgin” (sometimes be called “refined olive oil” or “light olive oil”) is another healthy option.

Though the word “refined” doesn’t exactly have a great reputation in the nutrition world, in this case it’s a game-changer, says Lakatos Shames. While refining olive oil strips out some antioxidants, it also raises its smoke point.

Bonus perks: regular ol’ olive oil is less expensive and has a more neutral flavour than EVOO.

Opt for light or refined olive oil for high-heat cooking like pan-frying.

Nutrition per tablespoon: 119 calories, 13.5 g fat (1.9 g saturated, 9.9 g monounsaturated, 1.4 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

5. Peanut Oil

Because it’s pretty much guaranteed to make everything taste like peanuts, peanut oil isn’t the best choice for every kind of cooking.

That said, it works great in any recipe that calls for peanut butter (think cookies, cakes, stews, etc.), or in Asian-inspired recipes, like stir-fries, that could benefit from some extra flavour.

Made up of mostly monounsaturated fats, peanut oil has a high smoke point and can handle whatever type of cooking you want to use it in.

Nutrition per tablespoon: 124 calories, 14 g fat, (2 g saturated, 6.7 g monounsaturated, 4.6 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

6. Algae Oil

“Algae oil contains lots of antioxidants and has a high smoke point,” Lakatos Shames says. Since it also has a neutral flavour, you can use it in just about any kind of cooking.

Just note that algae oil is relatively new to the market, so it tends to be a bit more expensive than other neutral oils.

Nutrition per tablespoon: 120 calories, 14 g fat (0.5 g saturated, 13 g monounsaturated, 0.5 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

7. Canola Oil

Maybe because it’s fairly cheap, or because it’s often used in not-so-healthy fried foods, canola oil gets a bad rap.

However, this oil is made up of mostly unsaturated fats and has a high smoke point, making it a versatile choice for cooking, say Lakatos and Lakatos Shames. When you want to treat yourself to something fried, canola oil can take the heat.

Nutrition per tablespoon: 124 calories, 14 g fat (1 g saturated, 8.9 g monounsaturated, 3.9 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

8. Beware: Vegetable Oils

Steer clear of bottles of oil simply identified as ‘vegetable oil.’ “When the oils aren’t specified and it’s just a mystery blend of oils, you don’t know what you’re getting,” says Lakatos.

Since some of these oils may have a lower smoke point, they’ll burn at a lower temperature, creating carcinogens (which aren’t great for long-term health) as they oxidize.

Nutrition per tablespoon: 122 calories, 13.5 g fat (13.4 g saturated, 0.2 g monounsaturated, 0.4 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

9. Beware: Palm Oil

Many snack foods and peanut butters contain palm oil, because it’s cheap and relatively shelf-stable.

However, while most oils have a relatively low environmental impact, the production of palm oil has been identified as a major contributor to deforestation in Southeast Asia, per the New York Times.

“It’s so environmentally damaging and very high in saturated fat,” Lakatos Shames says. Skip it, both for your health and the planet’s.

Nutrition per tablespoon: 120 calories, 13.6 g fat (6.7 g saturated, 5 g monounsaturated, 1.3 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

10. Proceed With Caution: Coconut Oil

And the ‘Most Controversial Oil of the Year’ award goes to…

Coconut oil is subject to both a lot of praise and a lot of criticism, and both are valid.

Trendy coconut oil is very stable and has a high smoke point, which make it well-suited for high-heat cooking, says Lakatos. Plus, it’s also relatively high in antioxidants.

However, it is high in saturated fat, and though some argue that saturated fat from plants isn’t as harmful as saturated fat from animals, research has yet to confirm the difference.

Still, Lakatos loves the slightly-sweet flavour, and sometimes sprays skillets with coconut oil for stovetop cooking.

While you don’t need need to cut the stuff out completely, don’t make it your go-to oil just yet.

Nutrition per tablespoon: 121 calories, 13.4 g fat (12.2 g saturated, 1 g monounsaturated, 0.2 g polyunsaturated), 0 mg sodium, 0 g carbs, 0 g sugar, 0 g fibre, 0 g protein

This article was originally published on www.womenshealthsa.co.za

Image credit: iStock

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Health24.com | WATCH: Cabin pressure – is the air toxic?

03 November 2019

WATCH: Cabin pressure – is the air toxic?

How healthy is the air you breathe in airplanes? We look into aerotoxic syndrome.

There have long been claims that cabin air contaminated by engine oil is putting at risk passenger health every year. But the airlines deny there is a problem. We look into aerotoxic syndrome.

Image credit: Unsplash

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Yoga teachers ‘risking serious hip problems’

Pushing their bodies to repeat the same yoga positions is leading to a rise in hip problems among teachers, a leading physio warns.

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Nurse Adopts Man with Autism so He Can Have Life-Saving Heart Transplant

An ICU nurse from Georgia adopted a 27-year-old man just two days after meeting him so he could fulfill the requirements for a life-saving heart transplant.

When Jonathan Pinkard fell ill last year, he was taken to Piedmont Newman Hospital, where doctors discovered he needed a heart transplant. If the news wasn’t scary enough, doctors then told Pinkard — who is on the autism spectrum — that he didn’t meet the requirements for a transplant, since one of the conditions is having a support system in place for post-operation recovery, he explained in a video posted to the hospital’s Facebook page.

“I was born and raised with my grandmother, and she passed away in 2012,” Pinkard said. “My mother, she’s in a rehab facility, and she can’t do much.”

Lori Wood, a nurse in the ICU, was assigned to care for Pinkard during his stay at Piedmont. After observing the obstacles Pinkard was facing, Wood felt compelled to help him during his time of need.

“At some point, you know, God places people in situations in your life and you have a choice to do something about it,” Wood, 57, said in the video. “I guess for me, with this situation, there was no choice.”

That’s when Wood asked Pinkard — just two days after meeting him — if she could become his legal guardian.

“I had a room, I was a nurse, I could take care of him,” she recalled. “It wasn’t really anything I struggled about. It was just something that had to happen. He had to come home with me.”

RELATED: Do Vaccines Really Cause Autism?

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“I had to help him. It was a no-brainer,” Wood added to Today. “He would have died without the transplant.”

About 20 people a day die awaiting organ transplants, according to the American Transplant Foundation, and there are over 114,000 people currently on the waiting list to receive a life-saving organ. One donor can save up to eight lives, the foundation says, and can save or enhance the lives of a hundred others.

Pinkard underwent a successful transplant in August, and has since moved in with Wood, who helps him take 34 pills a day, Today reported. She also drives him to doctor’s appointments and is hoping to teach him how to live independently.

RELATED VIDEO: Oklahoma Cop Adopts Abused Boy And His Baby Sister

The two have since bonded over watching Family Feud and sports.

“Jonathan has his chair, and I have my chair,” Wood told Today. “We like game shows and high-five back and forth if we get an answer right. He is very loving.”

“She treats me like one of her sons,” Pinkard told Today. “I am truly thank for that.”

“It’s kind of emotional, but at the same time, this has been a life journey for me,” he said in the hospital’s video. “If it weren’t for her, I wouldn’t be the person I am today.”

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