Health24.com | Heart attacks striking more young adults

Although Americans are suffering fewer heart attacks, the rate is dramatically increasing among those under 40.

In fact, 20% of people who have a heart attack are 40 or younger, a rate that has risen 2% a year for 10 years, new research reports.

Moving in the wrong direction

Some of these people are now in their 20s and early 30s, said senior study author Dr Ron Blankstein, a cardiologist at Brigham and Women’s Hospital in Boston. He said it used to be “incredibly rare” to see anyone under age 40 with a heart attack.

“Based on what we are seeing, it seems that we are moving in the wrong direction,” he said.

These young heart attack victims also have the same risks of dying from another heart attack or stroke as older patients.

“Even if you’re in your 20s or 30s, once you’ve had a heart attack, you’re at risk for more cardiovascular events and you have just as much risk as someone who may be older than you,” Blankstein said.

Risk factors such as diabetes, high blood pressure, smoking, family history of premature heart attack and high cholesterol were the same among older and young people who suffered a heart attack, researchers found.

Younger patients drank less alcohol but were more likely to be substance abusers – 18% used marijuana and 9% used cocaine.

Aggressive treatment

For the study, Blankstein and colleagues collected data on close to 2 100 patients under age 50 admitted to two hospitals for heart attacks.

“Many people think that a heart attack is destined to happen, but the vast majority could be prevented with earlier detection of the disease and aggressive lifestyle changes and management of other risk factors,” Blankstein said

To protect yourself, he recommends avoiding tobacco, getting regular exercise, eating a heart-healthy diet, losing weight if you need to, managing your blood pressure and cholesterol, avoiding diabetes, and staying away from cocaine and marijuana.

In a related study, Blankstein’s team found that one in five patients who suffer a heart attack before age 50 also have diabetes. Diabetics are more likely to have repeated heart attacks and die from a heart attack than other people.

These patients need aggressive treatment, Blankstein said. Some diabetes medications can reduce heart attack risk, he added.

The findings are to be presented March 17 at the American College of Cardiology’s annual meeting in New Orleans. Research presented at meetings is considered preliminary until published in a peer-reviewed journal.

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Health24.com | Hookah smoke can contain more toxins than cigarettes

Hookah users inhale high levels of toxic chemicals that endanger the heart and blood vessels.

That’s the stark warning in a new American Heart Association (AHA) scientific statement.

Impact on heart rate and blood pressure

A single half-hour session of smoking tobacco in a hookah typically exposes the user to more carbon monoxide than a single cigarette. Even short-term exposure to carbon monoxide in the water pipes is toxic and can reduce exercise capacity, according to the statement published in the journal Circulation.

Hookah smoke also contains other potentially harmful chemicals that can affect the heart and blood vessels, authors of the statement said. Those chemicals include nicotine, air pollutants, particulate matter, volatile organic chemicals, polycyclic aromatic hydrocarbons, acrolein, lead, cadmium and arsenic. Levels of most are higher in hookah smoke than cigarette smoke.

“Hookah smoke contains harmful substances and the American Heart Association strongly recommends avoiding the use of tobacco in any form,” said Aruni Bhatnagar, chairman of the group that wrote the scientific statement. He’s director of the University of Louisville Diabetes and Obesity Center.

Hookah smoking addictive

Evidence that hookah smoking has a serious impact on heart rate and blood pressure is mounting, and chronic use has been linked to an increased risk of coronary artery disease.

“Many young people mistakenly believe that smoking tobacco from a hookah is less harmful than cigarette smoking because the tobacco is filtered through water, but there is no scientific evidence that supports that claim,” Bhatnagar said in an AHA news release.

“However, there is evidence to suggest that hookah smoking is addictive and can lead to the use of other tobacco products such as cigarettes,” he said.

Nearly 5% of high school students and close to 14% of 18- to 24-year-olds in the United States use hookahs, recent surveys suggest. Young adults account for 55% of hookah smokers nationwide.

Hookah use is also associated with an increased likelihood of smoking cigarettes.

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McDonald’s: Tom Watson urges chain to drop Monopoly campaign

The campaign is a “danger to public health” as it encourages people to eat more, says MP Tom Watson.

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Health24.com | Parents, don’t be so quick to jump to an ADHD diagnosis

A growing number of US children are being diagnosed with attention-deficit/hyperactivity disorder.

But parents shouldn’t be too quick to get their child checked for ADHD, a child expert says.

“The key to determining if your child has the disorder is the consistent demonstration of at least six specific traits for a minimum of six months, and in two settings such as at home and at school,” said Ronald Brown.

“Also, the traits must be impairing how your child functions, and cause him or her to fall behind the normal development for his or her age,” he added.

Brown is dean of the University of Nevada, Las Vegas’ School of Allied Health Sciences.

People with ADHD have a number of traits within three main symptom categories: inattention, hyperactivity and impulsivity.

“Some people have problems within one of the groups and others exhibit characteristics within two or three,” Brown said.

Traits within the inattention symptom group may include: disorganisation; difficulty paying attention to details and a tendency to make careless mistakes; trouble staying on topic while talking, not listening to others, not following social rules; being easily distracted by things such as unimportant noises usually ignored by others.

Traits within the hyperactivity symptom group may include: fidgeting and squirming when seated; getting up frequently to walk or run around; running or climbing frequently at inappropriate times; and having trouble playing quietly.

Traits within the impulsivity symptom group may include: having a hard time waiting for a turn; blurting out answers before someone finishes asking a question; frequently interrupting or intruding on others; starting conversations at inappropriate times.

“Many of these symptoms happen from time to time in all youngsters, and sometimes among adults,” Brown said in a university news release.

“The difference between an active, imaginative child and one diagnosed with ADHD is functional impairment. Those with the disorder may have consistently poor academic performance, trouble interacting with peers and friends, and even challenges at home,” he explained.

Among American kids aged 4 to 17, there was a 42% increase in ADHD diagnoses between 2003 and 2011, according to the US Centers for Disease Control and Prevention.

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Health24.com | Irregular sleep could impact your heart health

It’s not just lack of sleep and poor sleep that can put the heart at risk – getting to bed on time may also matter, new research suggests.

The new study took the unique approach of looking at how much night-to-night difference a person had in sleep duration and what time he or she fell asleep. People with irregular sleep patterns had a higher risk for a cardiovascular event, including stroke, congestive heart failure and coronary heart disease, the study found.

Sleep-monitoring wrist devices

“Sleep regularity is an understudied area with critical relevance to everyone. Understanding its relationship with cardiovascular disease has important public health implications and may identify novel strategies for cardiovascular disease prevention,” said Tianyi Huang, lead author of the study presented this week at the American Heart Association’s Epidemiology and Prevention/Lifestyle and Cardiometabolic Health Scientific Sessions in Houston.

Researchers looked at data from nearly 2 000 people without cardiovascular disease at the start of the study. Participants wore sleep-monitoring wrist devices for seven-day periods from 2010 to 2013 and were followed for an average of four years. During that time, 95 people experienced or died from a stroke, heart failure or heart disease.

After adjusting for various factors, researchers found that people whose night-to-night sleep length during a seven-day period varied by more than two hours on average were 2.2 times more likely to have a cardiovascular event than people whose sleep length varied by an hour or less.

The time they fell asleep each night had a similar impact. Compared to people who went to bed within the same 30-minute window each night, those with a bedtime that varied by more than 90 minutes had double the risk of a cardiovascular event.

Digital distraction may be making the problem worse. Spending a lot of time staring at smartphones, tablets and other glowing screens could be messing with our sleep regularity, said Huang, an associate epidemiologist at Brigham and Women’s Hospital and Harvard Medical School.

“If our results are confirmed, the general public – particularly those at high risk for cardiovascular disease – needs to pay more attention to their sleep schedules,” he said. “People should be encouraged to reduce use of mobile devices or TV viewing before sleep to improve sleep regularity and maximise cardiometabolic benefits.”

A state of ‘jetlag’

Huang said the study is the first of its kind and called for larger studies with longer follow-ups, especially those that explore gender and age differences. He said studies are needed that focus on how irregular sleep is related to specific cardiovascular outcomes.

“I think it’s important for doctors to ask their patients about their sleep habits beyond the number of hours of sleep they get at night,” said sleep and nutrition researcher Marie-Pierre St-Onge. “Questions like, ‘How stable is your sleep?’ and ‘Do you have wide swings in the duration of sleep?’ would help to identify areas for improvement.”

St-Onge, an associate professor of nutritional medicine at Columbia University in New York City, was not involved in the new research and said the study seems to confirm that people with poor sleep habits can’t simply “catch up” on sleep.

“You can make an analogy between sleep and physical activity, where you have ‘weekend warriors’ who are absolutely sedentary during the week and then they hammer out two hours of physical activity in one day and think they’ll be fine. That’s not what we recommend, and it’s the same with sleep,” she said. “For optimal health, there has to be regularity to these behaviours, and that includes sleep.”

Another issue is that big changes in sleep timing can lead to a state of jetlag – referred to as “social jetlag” – without people even realising it.

“People might not have outward signs – they might not even feel sleepy or yawn, just like people don’t feel it if they have high blood pressure or high cholesterol levels. But the risk factor is still there,” she said. “People need to pay more attention and be more aware of the adverse impact poor sleep is having.”

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Health24.com | Raw dog food is risky business for pet and family alike

High levels of harmful bacteria found in many raw meat dog foods may be dangerous for more than just Fido, a new study suggests.

Not only can these foods put a dog at risk, but people who live with that dog, particularly the elderly, young and immunocompromised, are vulnerable, scientists say.

Harmful pathogens in raw food

“This research offers further compelling evidence to support vets’ concerns about the potential animal and public health risks associated with feeding pets a raw meat-based diet,” said veterinarian Dr Daniella Dos Santos. She is junior vice president of the British Veterinary Association.

“Bacteria such as E. coli and salmonella can cause significant gastrointestinal disease in animals,” Dos Santos explained.

“Pets can also shed potentially harmful pathogens present in raw food into their environment, so there is a risk to owners both in handling the food and coming into contact with the animal. Pet owners who choose to feed a raw food diet should be aware of the potential health risks and take full precautions while storing and handling the food,” she warned.

Raw meat-based diets have become popular for dogs in recent years. Unlike commercial dog foods, raw meat products are not heat-treated or freeze-dried to pasteurise their contents.

Researchers led by Dr Ingrid Hansson, from the Swedish University of Agricultural Sciences in Uppsala, Sweden, analysed samples from 60 packs of raw meat products for dogs. The food came from 10 different manufacturers in Sweden, Norway, Finland, Germany or England. The products contained either uncooked meat and/or edible bones and/or organs from cattle, chicken, lamb, turkeys, pigs, ducks, reindeer or salmon.

Dangers of E. coli

The samples were checked for bacteria that could potentially pose a health risk to animals and people: Enterobacteriaceae species; Clostridium perfringens, salmonella and campylobacter species.

All 60 samples contained Enterobacteriaceae species, which are indicators of faecal contamination. Levels varied, but 31 (52%) of the samples had levels above the European Union (EU) maximum of 5 000 bacteria per gram.

Most of the species detected in the samples are not known to cause infection, but E. coli – found in a third of the samples – does produce infection.

Another marker of faecal contamination and hygiene standards, C. perfringens, was found in 18 samples (30%). Two of the samples exceeded the maximum limits set by Swedish guidelines.

Salmonella and campylobacter bacteria can be passed from animals to people and cause infection. EU regulations don’t permit salmonella in any animal food.

But the researchers found salmonella in four (7%) of the samples, and campylobacter species were found in three samples from three different manufacturers.

Risk of antibiotic resistance

The study was published online in the journal Vet Record.

Raw meat dog food should be: kept frozen until use, and thawed at 50 degrees Fahrenheit (10 degrees Celsius); kept separate from other food; and handled with separate kitchen equipment or with equipment that is washed thoroughly after use, the researchers advised.

Never let dogs lick people’s faces immediately after they eat raw meat dog food. Also, don’t give dogs raw meat products it they’re being given antibiotics, because this could increase the risk of antibiotic resistance.

“Dogs in families with infants, elderly people or immunocompromised individuals should also not be fed [raw meat products], as these groups are more susceptible to infections,” Hansson’s team wrote.

The British Veterinary Association also does not recommend making a raw food diet at home without veterinary guidance due to the potential for nutritional deficiencies in homemade diets, Dos Santos said.

“We would advise any owner wanting to try a raw meat-based diet for their pet to first consult a veterinary surgeon,” she said in a journal news release.

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Health24.com | Treatment may allow allergic kids to eat eggs safely – study

An egg allergy is no joke, but some children who have it could safely eat eggs after immunotherapy treatment, a new study claims.

“Egg allergy is one of the most common food allergies and usually appears in early childhood. It has significant risk for severe allergic reactions and negatively affects quality of life for children with the allergy,” said first author Dr Edwin Kim, director of the Food Allergy Initiative at the University of North Carolina, Chapel Hill.

Though the allergy seems to go away with age, it can last into the second decade of life.

“Any treatment that can allow the introduction of egg into the diet of someone with egg allergy provides nutritional benefits and peace of mind for the patient and their family,” Kim said.

This study included 5- to 11-year-olds who were allergic to egg. Forty received egg oral immunotherapy (eOIT) treatment for up to four years; 15 received a placebo.

After patients completed eOIT, they were told to add concentrated egg (scrambled, fried or boiled) and/or baked egg (eggs used in cookies or a cake, for example) into their diet. For five years, they reported how much egg they ate and in what form, and how they felt afterward.

At the end of eOIT, half of the participants had sustained unresponsiveness (SU) to eggs, meaning eggs did not provoke an allergic reaction. Twenty-eight percent were desensitised, meaning they could eat about 2 teaspoons of pure egg without reaction, and 22% were not desensitized.

SU patients could eat both both baked and concentrated egg, while others had a higher risk of allergy symptoms.

“These results further support the effectiveness of eOIT as a safe way of desensitising children and youth with egg allergy,” Kim said in a university news release.

“Past research also suggests that eating egg may actually shorten the amount of time a patient has the allergy, so any amount of egg that is incorporated into an allergy patient’s diet is helpful.”

The study was presented recently at the American Academy of Allergy, Asthma and Immunology annual meeting in San Francisco.

Research presented at meetings is typically considered preliminary until published in a peer-reviewed journal.

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Nitrogen pollution’s path to streams weaves through more forests (and faster) than suspected

Nitrogen in rain and snow falls to the ground where, in theory, it is used by forest plants and microbes. New research by a scientific collaboration led by the USDA Forest Service shows that more nitrogen from rain and snow is making it to more streams than previously believed and flowing downstream in forests of the United States and Canada. The study, “Unprocessed atmospheric nitrate in waters of the Northern Forest Region in the USA and Canada,” was published this week in the journal Environmental Science & Technology.

Scientists found that some nitrate, which is a form of nitrogen that plants and microbes can use, occasionally moves too fast for biological uptake, resulting in “unprocessed” nitrate bypassing the otherwise effective filter of forest biology. The study links pollutant emissions from various and sometimes distant sources including industry, energy production, the transportation sector and agriculture to forest health and stream water quality.

“Nitrogen is critical to the biological productivity of the planet, but it becomes an ecological and aquatic pollutant when too much is present,” said Stephen Sebestyen, a research hydrologist with the USDA Forest Service’s Northern Research Station based in Grand Rapids, Minn., and the study’s lead author.

“From public land managers to woodlot owners, there is a great deal of interest in forest health and water quality. Our research identifies widespread pollutant effects, which undermines efforts to manage nitrogen pollution.”

Sebestyen and 29 co-authors completed one of the largest and longest examinations to trace unprocessed nitrate movement in forests. Scientists from several federal agencies and 12 academic institutions in the United States, Canada, and Japan collected water samples in 13 states and the province of Ontario, ultimately compiling more than 1,800 individual nitrate isotope analyses over the course of 21 years.

“We generally assumed that nitrate pollution would not travel a great distance through a forest because the landscape would serve as an effective filter,” Sebestyen said. “This study demonstrates that while we have not been wrong about that, we needed more information to be better informed.” Forests overall use most nitrate, unless rainfall and snowmelt runoff during higher flow events lead to brief, but important windows when unprocessed nitrate flows to streams; sometimes at levels that are unexpectedly high.

Too much nitrogen contributes to forest decline and growth of nuisance vegetation in lakes and ponds. Tree species have varying levels of tolerance for nitrogen. Too much nitrogen can change forest composition and provide a foothold for non-native plants. “I’m concerned with how air pollution affects forests and watersheds,” said Trent Wickman, an Air Resource Specialist with the USDA Forest Service’s Eastern Region and a co-author of the study. “There are a number of federal and state programs that aim to reduce nitrogen air pollution from vehicles and industrial sources. Understanding the fate of nitrogen that originates in the air, but ends up on land, is important to gauge the effectiveness of those pollution reduction programs.”

Sebestyen and the study’s co-authors suggest that because unprocessed nitrogen is not being filtered by natural vegetation to the extent previously believed, monitoring coupled with this baseline information is needed to give land managers a more nuanced view of forest health issues.

Story Source:

Materials provided by USDA Forest Service – Northern Research Station. Note: Content may be edited for style and length.

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Sweat holds most promise for noninvasive testing

Making a revolutionary biosensor takes blood, sweat and tears. And saliva, naturally.

University of Cincinnati professor Jason Heikenfeld examined the potential of these and other biofluids to test human health with tiny, portable sensors for the journal Nature Biotechnology.

Heikenfeld develops wearable technology in his Novel Device Lab in UC’s College of Engineering and Applied Science. His lab last year created the world’s first continuous-testing device that samples sweat as effectively as blood but in a noninvasive way and over many hours.

“Ultimately, technological advances in wearables are constrained by human biology itself,” the study said.

Remarkably, many of the innovations in the field of biosensors and sweat technology were developed in Cincinnati. The first glucose monitor for diabetes was commercialized in the region. The inventor of the the world’s first antiperspirant, called Odorono, was a Cincinnati physician named Abraham Murphey.

“We have such a strong history in this field here. It’s really fascinating,” Heikenfeld said.

Heikenfeld credits the hard work of his team for his lab’s success.

“We have been able to go far and fast here,” Heikenfeld said. “We resonate with a certain type of student. As much as we have brilliant faculty at UC, if we didn’t have talented students here, this technology wouldn’t exist. We would just be talking theoretically about the potential.”

In the Nature article, Heikenfeld identified four waves of discovery when it comes to testing human health. First, doctors began drawing and shipping blood to labs in an invasive, time-consuming and labor-intensive process that patients still undergo today.

Starting around the 1980s researchers, including pioneering UC engineering professor Chong Ahn, developed point-of-care lab tests that allowed doctors to get immediate results. Instead of shipping samples to a lab, doctors could test samples themselves using tiny self-contained devices.

“Dr. Ahn has been at the forefront of developing these point-of-care devices,” Heikenfeld said.

Now, Heikenfeld said, we’re in the midst of a third wave — continuous health monitoring with wearable devices like those developed at UC. These provide data over time so doctors can track health trends instead of relying on the snapshot that a single blood test provides.

“That’s super powerful because it tells me am I getting better? Am I getting worse?” Heikenfeld said.

Eventually, the field will see devices implanted in the body for long-term diagnosis or monitoring, he said. But first researchers will have to create robust sensors that can provide accurate information over a much longer time frame.

“That’s the big challenge,” Heikenfeld said. “Sensors are chemically reactive themselves. So they don’t last.”

After examining the use of saliva, tears and interstitial fluid, Heikenfeld concluded in the Nature article that sweat holds the most promise for noninvasive testing because it provides similar information as blood and its secretion rate can be controlled and measured.

In his Novel Device Lab at UC, Heikenfeld and his students have been creating new sensors on a wearable patch the size of a Band-Aid that stimulates sweat even when a patient is cool and resting. The sensor measures specific analytes over time that doctors can use to determine how the patient is responding to a drug treatment.

The sensors can be tailored to measure anything from drugs to hormones to dehydration, Heikenfeld said.

Last year the lab created the world’s first continuous-monitoring sensor that can record the same health information in sweat that doctors for generations have examined in blood. The milestone is remarkable because the continuous sensor allows doctors to track health over time to see whether a patient is getting better or worse. And they can do so in a noninvasive way with a tiny patch applied to the skin that stimulates sweat for up to 24 hours at a time.

“This is the Holy Grail. For the first time, we can show here’s the blood data; here’s the sweat data — and they work beautifully together,” Heikenfeld said.

Heikenfeld and his students published their latest experimental findings in December in the journal Lab on a Chip. UC’s study tracked how test subjects metabolized ethanol. The study concluded that sweat provided virtually the same information as blood to measure a drug’s presence in the body.

The latest breakthrough at UC marked the culmination of more than seven years of research, he said.

“For medications, we can use sweat to get an exact measurement of concentrations in the blood,” Heikenfeld said. “That’s important because once we can measure concentrations of therapeutics in blood, we can look at drug dosing. And that could make current dosing look like something from the Stone Age.”

Cincinnati is home to several companies that are turning technologies for drug prescribing, delivery and monitoring into commercial products. The list includes Assurex Health, Enable Injections and Heikenfeld’s Eccrine Systems, where he is co-founder and chief science officer.

Study co-author and computational biologist Tongli Zhang said devices like these will help doctors to provide personalized care. Zhang is an assistant professor in the Department of Pharmacology and Systems Physiology at the UC College of Medicine.

“You don’t give children the same drug dose as adults. Likewise, we can specify a dose based on a patient’s weight,” Zhang said. “But some patients might have liver or kidney failure. And others might metabolize a drug 10 times faster. So the same dose might be ineffective in some patients and toxic in others.”

Zhang said continuous sensors could change treatments in fundamental ways.

“Personalized or individualized medicine is becoming a bigger deal. We realize it’s important. If we can understand what’s going on in the body, we can tailor the treatment accordingly,” he said.

UC is at the forefront of developing new biosensors that Heikenfeld thinks will revolutionize the way we track disease and wellness.

“UC continues to build on our rich regional history in revolutionizing diagnostics through this third wave of continuous biochemical sensing,” he said.

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