Batteries store and release energy as ions shift between electrodes, usually through a liquid electrolyte. However, ORNL researchers engineered a battery in which sodium ions travel through a more durable and energy-packed solid electrolyte made with enhanced conductivity.

Solid electrolytes are considered the next frontier of batteries, if scientists can address challenges such as understanding how they fail in high-demand conditions. The ORNL-led team ran the battery under high current or voltage within a powerful X-ray beam. At the Advanced Photon Source at Argonne National Laboratory, researchers observed ions depositing in pores of the electrolyte, eventually forming structures that cause a short circuit.

“We can use this information to understand how to improve this really promising solid electrolyte material that could support storing renewable energy for longer periods,” said ORNL researcher Mengya Li.

Bacteria associated with inflammation is found in the gut in higher amounts roughly ten months before patients develop clinical rheumatoid arthritis, a longitudinal study by Leeds researchers has found.

Affecting more than half a million people in the UK, rheumatoid arthritis is a chronic disease that causes swelling, pain and stiffness in the joints because the immune system is mistakenly attacking the body’s healthy cells.

Previous research has linked rheumatoid arthritis to the gut microbiome, which is the ecosystem of microbes in your intestines. But this new study, published today in the Annals of the Rheumatic Diseases, reveals a potential intervention point.

Lead researcher Dr Christopher Rooney, NIHR Academic Clinical Lecturer at the University of Leeds and Leeds Teaching Hospitals NHS Trust, said: “Patients at risk of rheumatoid arthritis are already experiencing symptoms such as fatigue and joint pain, and they may know someone in their family who has developed the disease. As there is no known cure, at-risk patients often feel a sense of hopelessness, or even avoid getting tested.

“This new research might give us a major opportunity to act sooner to prevent rheumatoid arthritis.”

Major opportunity for treatment

Funded by Versus Arthritis, the longitudinal study was conducted on 19 patients at risk of rheumatoid arthritis, with samples taken five times during a 15-month period.

Five of these patients progressed to clinical arthritis, and the research showed they had gut instability with higher amounts of bacteria including Prevotella, which is associated with rheumatoid arthritis, about ten months before progression. The remaining 14, whose disease didn’t progress, had largely stable amounts of bacteria in their gut.

Potential treatments that the researchers want to test at the ten-month window include changes to diet like eating more fibre, taking prebiotics or probiotics, and improving dental hygiene to keep harmful bacteria from periodontal disease away from the gut.

The exact relationship between gut inflammation and rheumatoid arthritis development remains unclear. In a small number of patients within the study, the gut changes occurred before there were any changes to the joints observed by a rheumatologist, but more research is needed to determine whether these influence each other.

Although bacteria is associated with rheumatoid arthritis, the researchers want to make it clear that there is no evidence this is contagious.

Lucy Donaldson, director for research and health intelligence at Versus Arthritis, said: “At Versus Arthritis, we welcome the findings of this study which could give the clinicians of the future a crucial window of opportunity to delay — or even prevent — the onset of rheumatoid arthritis. This success is testament to the dedication of UK researchers who are working to personalise treatment and prevent chronic conditions that have significant impacts on a person’s ability to work, raise families and live independently.”

Years in the making

The research was carried out in collaboration with the National Institute for Health Research Leeds Biomedical Research Centre, under the research themes of Antimicrobial Resistance and Infection and Musculoskeletal Disease.

Leeds Teaching Hospitals NHS Trust, Versus Arthritis and Leeds Hospitals Charity were also partners on the project. Patients at Chapel Allerton Hospital helped to design the research to make stool sampling easier for participants.

The study initially took data from 124 individuals who had high levels of CCP+, an antibody that attacks healthy cells in the blood, which indicates risk of developing rheumatoid arthritis. The researchers compared their samples to 22 healthy individuals and seven people who had a new rheumatoid arthritis diagnosis.

The findings from this larger group showed that the gut microbiome was less diverse in the at-risk group, compared to the healthy control group.

The longitudinal study, which took samples from 19 patients over 15 months, revealed the changes in bacteria at ten months before progression to rheumatoid arthritis.

The Leeds research team will now carry out an analysis of treatments that have already been trialed, to inform future testing of treatments at this potential ten-month intervention point.

Students often appear for high-stakes tests that hold significant weight in determining their futures. One such examination, the Common Test for University Admissions, currently allows examinees using braille an extended examination time of 1.5 times the standard duration. However, with the recent increase in complex questions and questions involving charts and diagrams in such tests, it is necessary to review whether the current accommodations remain adequate.

The researchers assessed the validity of the current time extension for examination questions containing complex tables by measuring the time required to read the text and complex tables. The results showed that 70% of the examinees completed the braille text reading task within 1.5 times the standard duration and 100% completed it within double the duration. However, none of the examinees finished the braille table reading task within 1.5 or even double the extended time. Furthermore, the table reading task revealed considerable individual differences in reading speed, with no correlation observed between this task and braille text reading. This suggests that people who read braille sentences quickly cannot necessarily read braille tables at the same pace.

These findings demonstrate that the current time extension for examinees using braille is insufficient when examination questions include complex tables. This prompts a consideration of how to properly assess the abilities of such examinees and raises the broader question of how to evaluate the skills of each individual regardless of disability status. This research indicates the need to reconsider the current examination framework itself.

This work was supported by the Japan Society for the Promotion of Science (grant number 20H00822).

These massive ripples through the upper atmosphere, known as atmospheric gravity waves, appear in AWE’s images as concentric bands (artificially colored here in red, yellow, and blue) extending away from northern Florida.

“Like rings of water spreading from a drop in a pond, circular waves from Helene are seen billowing westward from Florida’s northwest coast,” said Ludger Scherliess, who is the AWE principal investigator at Utah State University in Logan.

Launched in November 2023 and mounted on the outside of the International Space Station, the AWE instrument looks down at Earth, scanning for atmospheric gravity waves, ripple-like patterns in the air generated by atmospheric disturbances such as violent thunderstorms, tornadoes, tsunamis, wind bursts over mountain ranges, and hurricanes. It does this by looking for brightness fluctuations in colorful bands of light called airglow in Earth’s mesosphere. AWE’s study of these gravity waves created by terrestrial weather helps NASA pinpoint how they affect space weather.

These views of gravity waves from Hurricane Helene are among the first publicly released images from AWE, confirming that the instrument has the sensitivity to reveal the impacts hurricanes have on Earth’s upper atmosphere.

In 79 AD, Mount Vesuvius experienced one of its most significant eruptions, burying the Roman city of Pompeii and its inhabitants under a thick layer of small stones and ash known as lapilli. Many of Pompeii’s inhabitants lost their lives as their homes collapsed under the weight of the lapilli raining down from many kilometres above. Those who survived the initial phase of the eruption eventually succumbed to the dangerous pyroclastic flows. This fast-moving stream of hot gas and volcanic matter instantly enveloped their bodies in a solid layer of ash, effectively preserving their bodies, including their features.

Since the 1800s, casts had been made by pouring plaster into the voids left by these bodies after their decay. The research team extracted DNA from the heavily fragmented skeletal remains embedded in 14 of the 86 famous casts undergoing restoration. This extraction process allowed them to accurately establish genetic relationships, determine sex and trace ancestry. Interestingly, their findings largely contradicted previous assumptions based solely on physical appearance and the positioning of the casts.

Genetic relationships of victims revisited

“This research shows how genetic analysis can significantly add to the stories constructed from archaeological data,” says Professor David Caramelli, from the Department of Anthropology at the University of Florence. “The findings challenge enduring notions such as the association of jewellery with femininity or the interpretation of physical proximity as evidence of familial relationships.” “Moreover,” Caramelli adds, “the genetic evidence adds a layer of complexity to simple kinship narratives. For example, in the House of the Golden Bracelet, the only site where we have genetic information from multiple individuals, the four people traditionally thought to be the two parents and their children actually have no genetic ties to each other.”

“The scientific data we provide do not always align with common assumptions,” says David Reich of Harvard University. “For instance, one notable example is the discovery that an adult wearing a golden bracelet and holding a child, traditionally interpreted as a mother and child, were an unrelated adult male and child. Similarly, a pair of individuals thought to be sisters, or mother and daughter, were found to include at least one genetic male. These findings challenge traditional gender and familial assumptions.”

Cosmopolitan nature of the Roman Empire

The genetic data also provided information about the ancestry of the Pompeians, who had different genomic backgrounds. The finding that they were mainly descended from recent immigrants from the eastern Mediterranean highlights the cosmopolitan nature of the Roman Empire.

“Our findings have significant implications for the interpretation of archaeological data and the understanding of ancient societies,” says Alissa Mittnik of the Max Planck Institute for Evolutionary Anthropology. “They highlight the importance of integrating genetic data with archaeological and historical information to avoid misinterpretations based on modern assumptions. This study also underscores the diverse and cosmopolitan nature of Pompeii’s population, reflecting broader patterns of mobility and cultural exchange in the Roman Empire.”

“It is also likely that the use of these casts for narration purposes could have led to past restorers modifying their postures and placements,” adds David Caramelli. “The combined use of genetic data and other bioarchaeological methods provides us with the chance to better comprehend the lives and habits of the victims of the Vesuvius eruption.”

Gabriel Zuchtriegel, Director of the Pompeii Park, says, “The Pompeii Park has been including ancient DNA analysis in its study protocols for years, not only for human victims, but also for animal victims.” He explains that the Park manages a variety of research projects through its own laboratory. These include isotopic analysis, diagnostics, geology, volcanology and, in particular, reverse engineering. He stresses that “all these elements together contribute to a comprehensive, updated interpretation of the archaeological findings. These efforts are turning Pompeii into a veritable incubator for the development of new methods, resources and scientific comparisons.” Zuchtriegel concludes: “From this point of view, this study marks a true change in perspective, in which the site itself plays a central role in advancing archaeology and research.”

The research, published today in The Astrophysical Journal Letters, introduces a method that could provide direct evidence of photons circling black holes due to an effect known as “gravitational lensing.”

Gravitational lensing occurs when light passes near a black hole and its path is bent by the black hole’s strong gravitational field. The effect allows the light to take multiple paths from a source to an observer on Earth: some light rays might follow a direct route while others could loop around the black hole once — or multiple times — before reaching us. This means that light from the same source can arrive at different times, resulting in an “echo.”

“That light circles around black holes, causing echoes, has been theorized for years, but such echoes have not yet been measured,” says the study’s lead author, George N. Wong, Frank and Peggy Taplin Member in the Institute’s School of Natural Sciences and Associate Research Scholar at the Princeton Gravity Initiative at Princeton University. “Our method offers a blueprint for making these measurements, which could potentially revolutionize our understanding of black hole physics.”

The technique allows the faint echo signatures to be isolated from the stronger direct light captured by well-known interferometric telescopes, such as the Event Horizon Telescope. Both Wong and one of his co-authors, Lia Medeiros, Visitor in the Institute’s School of Natural Sciences and NASA Einstein Fellow at Princeton University, have worked extensively as part of the Event Horizon Telescope Collaboration.

To test their technique, Wong and Medeiros, working alongside James Stone, Professor in the School of Natural Sciences, and Alejandro Cárdenas-Avendaño, Feynman Fellow at Los Alamos National Laboratory and former Associate Research Scholar at Princeton University, ran high-resolution simulations which took tens of thousands of “snapshots” of light traveling around a supermassive black hole akin to that at the center of the M87 galaxy (M87*), which is located around 55 million light-years away from Earth. Using these simulations, the team demonstrated that their method could directly infer the echo delay period in the simulated data. They believe that their technique will be applicable to other black holes, in addition to M87*.

“This method will not only be able to confirm when light orbiting a black hole has been measured, but will also provide a new tool for measuring the black hole’s fundamental properties,” explains Medeiros.

Understanding these properties is important. “Black holes play a significant role in shaping the evolution of the universe,” says Wong. “Even though we often focus on how black holes pull things in, they also eject large amounts of energy into their surroundings. They play a major role in the development of galaxies, affecting how, when, and where stars form, and helping to determine how the structure of the galaxy itself evolves. Knowing the distribution of black hole masses and spins, and how the distribution changes over time, greatly enhances our understanding of the universe.”

Measuring the mass or spin of a black hole is tricky. The nature of the accretion disk, namely the rotating structure of hot gas and other matter spiraling inward towards a black hole, can “confuse” the measurement, Wong notes. Light echoes provide an independent measurement of the mass and spin, however, and having multiple measurements allows us to produce an estimate for those parameters “that we can really believe in,” states Medeiros.

Detecting light echoes might also enable scientists to better test Albert Einstein’s theories of gravity. “Using this technique, we might find things that make us think ‘hey, this is weird!'” adds Medeiros. “The analysis of such data could help us to verify whether black holes are indeed consistent with general relativity.”

The team’s results suggest that it may be possible to detect echoes with a pair of telescopes — one on Earth and one in space — working together to perform what can be described as “very long baseline interferometry.” Such an interferometric mission need only be “modest,” states Wong. Their technique provides a tractable, practical method to gather important, reliable information about black holes.