To avoid a bottleneck of bots, a team of MIT engineers is designing a kit of universal robotic parts that an astronaut could easily mix and match to rapidly configure different robot “species” to fit various missions on the moon. Once a mission is completed, a robot can be disassembled and its parts used to configure a new robot to meet a different task.

The team calls the system WORMS, for the Walking Oligomeric Robotic Mobility System. The system’s parts include worm-inspired robotic limbs that an astronaut can easily snap onto a base, and that work together as a walking robot. Depending on the mission, parts can be configured to build, for instance, large “pack” bots capable of carrying heavy solar panels up a hill. The same parts could be reconfigured into six-legged spider bots that can be lowered into a lava tube to drill for frozen water.

“You could imagine a shed on the moon with shelves of worms,” says team leader George Lordos, a PhD candidate and graduate instructor in MIT’s Department of Aeronautics and Astronautics (AeroAstro), in reference to the independent, articulated robots that carry their own motors, sensors, computer, and battery. “Astronauts could go into the shed, pick the worms they need, along with the right shoes, body, sensors and tools, and they could snap everything together, then disassemble it to make a new one. The design is flexible, sustainable, and cost-effective.”

Lordos’ team has built and demonstrated a six-legged WORMS robot. Last week, they presented their results at IEEE’s Aerospace Conference, where they also received the conference’s Best Paper Award.

MIT team members include Michael J. Brown, Kir Latyshev, Aileen Liao, Sharmi Shah, Cesar Meza, Brooke Bensche, Cynthia Cao, Yang Chen, Alex S. Miller, Aditya Mehrotra, Jacob Rodriguez, Anna Mokkapati, Tomas Cantu, Katherina Sapozhnikov, Jessica Rutledge, David Trumper, Sangbae Kim, Olivier de Weck, Jeffrey Hoffman, along with Aleks Siemenn, Cormac O’Neill, Diego Rivero, Fiona Lin, Hanfei Cui, Isabella Golemme, John Zhang, Jolie Bercow, Prajwal Mahesh, Stephanie Howe, and Zeyad Al Awwad, as well as Chiara Rissola of Carnegie Mellon University and Wendell Chun of the University of Denver.

Animal instincts

WORMS was conceived in 2022 as an answer to NASA’s Breakthrough, Innovative and Game-changing (BIG) Idea Challenge — an annual competition for university students to design, develop, and demonstrate a game-changing idea. In 2022, NASA challenged students to develop robotic systems that can move across extreme terrain, without the use of wheels.

A team from MIT’s Space Resources Workshop took up the challenge, aiming specifically for a lunar robot design that could navigate the extreme terrain of the moon’s South Pole — a landscape that is marked by thick, fluffy dust; steep, rocky slopes; and deep lava tubes. The environment also hosts “permanently shadowed” regions that could contain frozen water, which, if accessible, would be essential for sustaining astronauts.

As they mulled over ways to navigate the moon’s polar terrain, the students took inspiration from animals. In their initial brainstorming, they noted certain animals could conceptually be suited to certain missions: A spider could drop down and explore a lava tube, a line of elephants could carry heavy equipment while supporting each other down a steep slope, and a goat, tethered to an ox, could help lead the larger animal up the side of a hill as it transports an array of solar panels.

“As we were thinking of these animal inspirations, we realized that one of the simplest animals, the worm, makes similar movements as an arm, or a leg, or a backbone, or a tail,” says deputy team leader and AeroAstro graduate student Michael Brown. “And then the lightbulb went off: We could build all these animal-inspired robots using worm-like appendages.'”

Snap on, snap off

Lordos, who is of Greek descent, helped coin WORMS, and chose the letter “O” to stand for “oligomeric,” which in Greek signifies “a few parts.”

“Our idea was that, with just a few parts, combined in different ways, you could mix and match and get all these different robots,” says AeroAstro undergraduate Brooke Bensche.

The system’s main parts include the appendage, or worm, which can be attached to a body, or chassis, via a “universal interface block” that snaps the two parts together through a twist-and-lock mechanism. The parts can be disconnected with a small tool that releases the block’s spring-loaded pins.

Appendages and bodies can also snap into accessories such as a “shoe,” which the team engineered in the shape of a wok, and a LiDAR system that can map the surroundings to help a robot navigate.

“In future iterations we hope to add more snap-on sensors and tools, such as winches, balance sensors, and drills,” says AeroAstro undergraduate Jacob Rodriguez.

The team developed software that can be tailored to coordinate multiple appendages. As a proof of concept, the team built a six-legged robot about the size of a go-cart. In the lab, they showed that once assembled, the robot’s independent limbs worked to walk over level ground. The team also showed that they could quickly assemble and disassemble the robot in the field, on a desert site in California.

In its first generation, each WORMS appendage measures about 1 meter long and weighs about 20 pounds. In the moon’s gravity, which is about one-sixth that of Earth’s, each limb would weigh about 3 pounds, which an astronaut could easily handle to build or disassemble a robot in the field. The team has planned out the specs for a larger generation with longer and slightly heavier appendages. These bigger parts could be snapped together to build “pack” bots, capable of transporting heavy payloads.

“There are many buzz words that are used to describe effective systems for future space exploration: modular, reconfigurable, adaptable, flexible, cross-cutting, et cetera,” says Kevin Kempton, an engineer at NASA’s Langley Research Center, who served as a judge for the 2022 BIG Idea Challenge. “The MIT WORMS concept incorporates all these qualities and more.”

This research was supported, in part, by NASA, MIT, the Massachusetts Space Grant, the National Science Foundation, and the Fannie and John Hertz Foundation.

Video: https://youtu.be/U72lmSXEVkM

Massive stars race through their lifecycles, and only some of them go through a brief Wolf-Rayet phase before going supernova, making Webb’s detailed observations of this rare phase valuable to astronomers. Wolf-Rayet stars are in the process of casting off their outer layers, resulting in their characteristic halos of gas and dust. The star WR 124 is 30 times the mass of the Sun and has shed 10 Suns’ worth of material — so far. As the ejected gas moves away from the star and cools, cosmic dust forms and glows in the infrared light detectable by Webb.

The origin of cosmic dust that can survive a supernova blast and contribute to the universe’s overall “dust budget” is of great interest to astronomers for multiple reasons. Dust is integral to the workings of the universe: It shelters forming stars, gathers together to help form planets, and serves as a platform for molecules to form and clump together — including the building blocks of life on Earth. Despite the many essential roles that dust plays, there is still more dust in the universe than astronomers’ current dust-formation theories can explain. The universe is operating with a dust budget surplus.

Webb opens up new possibilities for studying details in cosmic dust, which is best observed in infrared wavelengths of light. Webb’s Near-Infrared Camera (NIRCam) balances the brightness of WR 124’s stellar core and the knotty details in the fainter surrounding gas. The telescope’s Mid-Infrared Instrument (MIRI) reveals the clumpy structure of the gas and dust nebula of the ejected material now surrounding the star. Before Webb, dust-loving astronomers simply did not have enough detailed information to explore questions of dust production in environments like WR 124, and whether the dust grains were large and bountiful enough to survive the supernova and become a significant contribution to the overall dust budget. Now those questions can be investigated with real data.

Stars like WR 124 also serve as an analog to help astronomers understand a crucial period in the early history of the universe. Similar dying stars first seeded the young universe with heavy elements forged in their cores — elements that are now common in the current era, including on Earth.

Webb’s detailed image of WR 124 preserves forever a brief, turbulent time of transformation, and promises future discoveries that will reveal the long-shrouded mysteries of cosmic dust.

Researchers from the University of Cambridge carried out a study in a tech consultancy firm using two different robot wellbeing coaches, where 26 employees participated in weekly robot-led wellbeing sessions for four weeks. Although the robots had identical voices, facial expressions, and scripts for the sessions, the robots’ physical appearance affected how participants interacted with it.

Participants who did their wellbeing exercises with a toy-like robot said that they felt more of a connection with their ‘coach’ than participants who worked with a humanoid-like robot. The researchers say that perception of robots is affected by popular culture, where the only limit on what robots can do is the imagination. When faced with a robot in the real world however, it often does not live up to expectations.

Since the toy-like robot looks simpler, participants may have had lower expectations and ended up finding the robot easier to talk connect with. Participants who worked with the humanoid robot found that their expectations didn’t match reality, since the robot was not capable of having interactive conversations.

Despite the differences between expectations and reality, the researchers say that their study shows that robots can be a useful tool to promote mental wellbeing in the workplace. The results will be reported today (15 March) at the ACM/IEEE International Conference on Human-Robot Interaction in Stockholm.

The World Health Organization recommends that employers take action to promote and protect mental wellbeing at work, but the implementation of wellbeing practices is often limited by a lack of resources and personnel. Robots have shown some early promise for helping address this gap, but most studies on robots and wellbeing have been conducted in a laboratory setting.

“We wanted to take the robots out of the lab and study how they might be useful in the real world,” said Dr Micol Spitale, the paper’s first author.

The researchers collaborated with local technology company Cambridge Consultants to design and implement a workplace wellbeing programme using robots. Over the course of four weeks, employees were guided through four different wellbeing exercises by one of two robots: either the QTRobot (QT) or the Misty II robot (Misty).

The QT is a childlike humanoid robot and roughly 90cm tall, while Misty is a 36cm tall toy-like robot. Both robots have screen faces that can be programmed with different facial expressions.

“We interviewed different wellbeing coaches and then we programmed our robots to have a coach-like personality, with high openness and conscientiousness,” said co-author Minja Axelsson. “The robots were programmed to have the same personality, the same facial expressions and the same voice, so the only difference between them was the physical robot form.”

Participants in the experiment were guided through different positive psychology exercises by a robot in an office meeting room. Each session started with the robot asking participants to recall a positive experience or describe something in their lives they were grateful for, and the robot would ask follow-up questions. After the sessions, participants were asked to assess the robot with a questionnaire and an interview. Participants did one session per week for four weeks, and worked with the same robot for each session.

Participants who worked with the toy-like Misty robot reported that they had a better working connection with the robot than participants who worked with the child-like QT robot. Participants also had a more positive perception of Misty overall.

“It could be that since the Misty robot is more toy-like, it matched their expectations,” said Spitale. “But since QT is more humanoid, they expected it to behave like a human, which may be why participants who worked with QT were slightly underwhelmed.”

“The most common response we had from participants was that their expectations of the robot didn’t match with reality,” said Professor Hatice Gunes from Cambridge’s Department of Computer Science and Technology, who led the research. “We programmed the robots with a script, but participants were hoping there would be more interactivity. It’s incredibly difficult to create a robot that’s capable of natural conversation. New developments in large language models could really be beneficial in this respect.”

“Our perceptions of how robots should look or behave might be holding back the uptake of robotics in areas where they can be useful,” said Axelsson.

Although the robots used in the experiment are not as advanced as C-3PO or other fictional robots, participants still said they found the wellbeing exercises helpful, and that they were open to the idea of talking to a robot in future.

“The robot can serve as a physical reminder to commit to the practice of wellbeing exercises,” said Gunes. “And just saying things out loud, even to a robot, can be helpful when you’re trying to improve mental wellbeing.”

The team is now working to enhance the robot coaches’ responsiveness during the coaching practices and interactions.

The research was supported by the Engineering and Physical Sciences Research Council (EPSRC), part of UK Research and Innovation (UKRI). Hatice Gunes is a Staff Fellow of Trinity Hall, Cambridge.

Three research teams led by Professor Hyung Joon Cha of the Chemical Engineering Department at Pohang University of Science and Technology (POSTECH), Professor Yun Kee Jo of the School of Convergence at Kyungpook National University (KNU), and Professor Sang Ho Jun of the Department of Oral and Maxillofacial Surgery at Korea University Anam Hospital together developed an osteogenic barrier coating material for dental implants that prevents the invasion of soft tissue cells, attracts osteo-progenitor cells including bone stem cells, and sustainably releases the loaded bone morphogenetic protein-2 (BMP-2), significantly facilitating bone regeneration.

GBR is widely used in dental implant placement. It maintains the space for bones to grow and prevents cells other than osteogenic cells, such as fibroblasts, from populating the bone defect sites, allowing the bone to grow without interference by non-osteogenic cells. However, the GBR approach is still less likely to be successful and requires longer treatment time for those patients with insufficient bone quantity and quality. Depending on the configurations of defect sites, preventing the invasion of the non-osteogenic cells by using barrier membranes alone is not enough to significantly facilitate the bone regeneration.

The joint research team first loaded BMP-2 on top of the bioengineered material where RGD peptide, cell recognitive motif that is capable of attracting cells, is fused with mussel adhesive protein (MAP) that maintains strong adhesiveness in a wet environment. The team then coated the titanium mesh (Ti-mesh) membrane with it. According to the research findings, the coated barrier membrane exhibited cell occlusivity where fibroblasts could not permeate the membrane. The team also found that it induced a high level of bone differentiation in a short period of time inside the membrane by means of high growth of mesenchymal stem cells and release of BMP-2.

Application of the developed MAP-based barrier coating for guided bone regeneration to a titanium membrane in a rat calvarial defect model showed that the coating roughly doubled the speed of bone tissue regeneration.

Professor Hyung Joon Cha who led the research said, “This research was conducted based on long-term research cooperation of the joint research team in the area of bone regeneration for implant placement. Its findings revealed the possibility of improving the success rate of implant treatment regardless of the bone condition.” He added that the research findings could also be applied to regenerate a variety of hard tissues.

The research findings were published in the online edition of the Bioengineering & Translational Medicine, a distinguished journal in the field of bioengineering and regenerative medicine. The study was conducted as a part of the Dentistry Technology R&D Project under the Korea Health Technology R&D Project funded by the Ministry of Health & Welfare, the High Value-added Food Technology Development Program funded by the Ministry of Agriculture, Food & Rural Affairs, and the BK21 Four Program by the National Research Foundation of Korea.

Researchers from UNSW Sydney and the Australian Institute of Botanical Science, part of the Royal Botanic Gardens and Domain Trust, surveyed 33 major online databases of plant photographs to examine the photographic record of Australian plant species. The findings, published in New Phytologist, reveal out of 21,077 native Australian vascular plant species, almost 20 per cent lack a verifiable photograph.

Lead author of the study and UNSW Science PhD student Thomas Mesaglio says Australia is one of the richest areas in the world for native species.

“It was surprising to see how many plant species had just line drawings, illustrations, paintings, or even no media at all,” Mr Mesaglio says.

Dr Hervé Sauquet, co-author of the study and Senior Research Scientist at the Australian Institute of Botanical Science, is based at the National Herbarium of New South Wales.

“All species of plants ultimately rely on specimens in herbarium collections for their identification,” Dr Sauquet says. “Yet, even in this digital age where most herbarium specimens have been scanned and are accessible on the web, photos of live plants in the wild remain in critical need.”

Senior author of the study from UNSW Science Associate Professor Will Cornwell says a lack of detailed photos can have real consequences. Many plant species that are difficult to identify in the wild may go extinct if scientists cannot properly identify them with the help of photos.

“We had assumed every plant species would have simply been photographed by someone, somewhere, throughout history. But it turns out this isn’t the case,” says A/Prof. Cornwell.

“This is where citizen scientists can come in and help us fill this gap with their photos.”

Gaps in the photographic record

Photographs can help botanists and taxonomists who work with plant specimens by preserving characteristics like flower colour that get lost over time in their samples. They can also show additional features, such as the orientation of leaves or bark appearance, and add ecological context.

“Having a comprehensive photographic set helps us to be confident in our identifications,” Mr Mesaglio says. “Particularly when it is practically challenging to collect and preserve the entire plant, photos complement the physical voucher by showing the soil type, the habitat it’s growing in, and other species growing alongside it.”

But it turns out not all plant groups are photographed equally. Just as some animals receive less attention than others, there might also be a bias against less charismatic plants.

The study found the most well-photographed plant groups tend to be shrubs or trees with more noticeable or spectacular features, such as colourful flowers. Banksia, for example, is one of only two Australian plant genera with more than 40 species to have a complete photographic record. Meanwhile, the family with the most significant photo deficit was Poaceae — commonly known as grasses — with 343 unphotographed species.

“We noticed a charisma deficit, so the species that tend to be harder to see are the ones missing out,” Mr Mesaglio says. “They may have innocuous or pale-looking flowers or be smaller and harder to spot grasses, sedges and herbs.”

Geography also affected the photographic record. While most species across the south-eastern states of Australia have comprehensive records, Western Australia had the largest void, with 52 per cent of all unphotographed species found there.

“The primary ‘hotspots’ for unphotographed Australian plants are areas with high plant diversity, but the environments are rugged and often difficult to access, particularly by road,” Mr Mesaglio says. “But it means there’s an exciting opportunity to visit these locations because we might capture something that has never before been photographed.”

Activating citizen scientist snaps

It’s one thing to have comprehensive photographic records for professional scientists to use in identification guides. But when the plant world is under threat from multiple fronts, including habitat clearing and climate change, photos can help engage the public in plant science.

“People can engage with, sympathise with, and get much more excited about plants with photographs, which is vital when our natural environments are more at risk than ever,” Mr Mesaglio says.

“Because digital photography is so accessible now, anyone can also help make a meaningful contribution to science using the camera in their pocket.”

Using a platform like iNaturalist, keen citizen scientists can have their snaps identified by experts and share the data with aggregators like the Atlas of Living Australia and the Global Biodiversity Information Facility to be used in research and conservation.

“Since April last year, we’ve identified nearly 10 per cent of those previously unphotographed species thanks to members of the public uploading their photographs and experts who’ve kindly identified them,” Mr Mesaglio says. “There could be many more in personal collections or behind paywalls just waiting to be shared.”

The researchers recommend a standardised system for scientific plant photography be developed, starting with a requirement in the International Code of Nomenclature for Plants to include at least one field photograph where possible in new species descriptions. They also suggest all new species descriptions be published as Open Access in searchable databases with Creative Commons licensing to maximise their usage.

“We also suspect more photos exist, but they’re hidden away on social media or behind scientific paywalls that aren’t accessible, discoverable, or searchable,” Mr Mesaglio says.

“Of the species with photographs, many have a single photo. We not only want to capture those unrepresented species but also continue building the photographic record for all species.

“Doing so will help us identify, monitor and conserve our native species for generations to come.”

But they also tend to have good intentions, the study found.

The study, published this week in the Journal of Medical Internet Research, provides some of the first insights into the burgeoning, loosely regulated world of so-called “patient influencers,” sharing findings from 26 in-depth interviews about why and how they do it.

“The bottom line here is that patient influencers act as a form of interactive direct-to-consumer (DTC) advertising, sharing their knowledge and experiences on pharmaceutical drugs with communities of followers in which they wield great influence,” said author Erin Willis, an associate professor of advertising, public relations and media design. “This raises ethical questions that need more investigation.”

The study comes amid growing concerns about the harmful consequences of drug promotion on social media.

In recent weeks, in the wake of a slew of TikTok videos and Twitter posts touting the weight loss benefits of the diabetes drug Ozempic, patients who need the medication to manage their disease have faced global shortages. Meanwhile, those taking it “off-label” to slim down have experienced surprising side-effects, including violent diarrhea and extreme facial thinning.

“This is a great example of the power of social media and the unintended consequences,” said Willis.

A new kind of advertising

Controversial from its start in the 1980s, and still only available in the United States and New Zealand, DTC advertising enables drug companies to target consumers directly, rather than exclusively through physicians. About half of the people who ask their doctor about a drug after seeing a TV ad get it.

With trust in pharmaceutical companies and traditional media declining, drug makers are now turning to real patients as messengers, with companies like Health Union connecting them for partnerships.

Willis conducted one-on-one, hour-long Zoom interviews with influencers with a range of conditions, including lupus, fibromyalgia, Parkinson’s disease, asthma, HIV, celiac disease, chronic migraines and perimenopause. Eighteen of the 26 collaborated with a pharmaceutical company in some way.

Most had between 1,000 and 40,000 followers. Such “micro influencers” tend to be less expensive for advertisers to work with than celebrities, and research has shown they have the most influence on purchasing behaviors, said Willis.

Some interviewees posted company press releases directly. Others read studies about drugs and translated results for followers. Some were paid to post content for drug companies.

“Health literacy and digital literacy are both concerningly low in this country,” said Willis, noting that consumers often fail to recognize the difference between a sponsored ad and an altruistic personal post. “The fact that patients with no medical training are broadly sharing drug information should alarm us.”

Good intentions

On the positive side, Willis was heartened by the reasons participants become influencers.

Almost all said they were drawn to their roles by a sense that the answers they sought as patients, didn’t exist in other channels.

“I spent a lot of time looking for diabetes information that related to me — an African American woman from the South,” reported one study participant. “I didn’t see what I needed, so I created it.”

Others were motivated by a wish to destigmatize disability in certain communities.

“There’s still not a lot of talk about Latinos and HIV,” said another participant. “When there was information, it wasn’t culturally appropriate.”

Five said they never share information about drugs, stating that they believed it was “borderline unethical.”

Others said they would only post about drugs they personally had been prescribed and taken and always encouraged followers to consult with their doctor. They all said they generally strived to behave ethically.

“It’s comforting that the people we interviewed generally want to stay abreast of the science and be a credible source,” said Willis. “But I also know that doctors go to medical school for a reason.”

Concerns abound

Several influencers reported that followers frequently private message them to get detailed information about dosage and side effects.

“In an online community, there are other people there to say, ‘That’s not true or that’s not what I experienced.'” Willis said. “But with social media, a lot of the conversation happens privately.”

Willis also worries that influencers may stress the upsides of medications without fully disclosing the side-effects. For instance, she references a famously controversial 2015 post by celebrity influencer Kim Kardashian, singing the praises of a “#morningsickness” drug called Diclegis to her tens of millions of followers on Instagram.

The Food and Drug Administration swiftly flagged the post for omitting the drug’s long list of risks, required Kardashian to remove the post and dinged the drug maker with a warning letter. The Federal Trade Commission (FTC) now requires influencers to disclose whether they are paid via hashtags, such as #ad or #sponcon, and the Food and Drug Administration has rules on what can be said on social posts. But those rules are open to interpretation, and videos, disappearing content and direct messaging can be tough to track.

Willis acknowledged that her sample was a small one and that because many of her interviewees were referred to her by Health Union, they likely skew to the responsible side. In future studies, she intends to include broader sample sizes, explore how influencers impact treatment decisions and investigate compensation for and regulations around patient influencers.

Analysts predict the influencer marketing industry as a whole will be valued at $21.1 billion in 2023.

As patient influencers increasingly find their place in it, Willis contends that regulators should work harder to keep up with all the new platforms.

“This is happening, with or without regulation, and people should be aware of it,” Willis said.