Health24.com | 3 lines of defence in treating hyperpigmentation

In partnership with SA’s top medical aesthetic companies 

As discussed in 5 possible causes of pigmentation problems, the type of pigmentation – and whether it’s superficial (epidermal) or deep-seated (dermal), or even both – determines how this common and distressing problem should be treated.

The aim of all treatments is to break down and remove existing pigmentation and to prevent new pigmentation from forming. How they achieve this, however, differs in the techniques used, intensity of treatment,and also the cost of treatment.

First line of defence: Superficial options

Using a safe and effective cosmeceutical skin treatment is your most accessible option, and will often be used alongside any other form of treatment, as well as for aftercare.

NeoStrata’s Enlighten range is a complete skincare routine, from cleanser to serum, which work together to provide lasting brightening and skin tone evening-out results. The dermatologist-recommended range uses advanced ingredients to tackle the various causes of hyperpigmentation.

The star product, Enlighten Illuminating Serum, contains 12 active brighteners (both patented and clinically proven) that target six pigment control systems to help break up and reduce the appearance of existing pigmentation and discourage new spots from forming.

Obagi Medical’s Nu-Derm Fx system penetrates the skin’s surface to correct the damage within, zeroing in on age spots, hyperpigmentation, skin yellowing and redness, as well as roughness. Available in systems for Normal to Dry and Normal to Oily skin, Obagi Nu-Derm is so effective because of the active ingredient,  Arbutin which is present in a 7% concentration. This natural hydroquinone derivative extracted from bearberries is a very powerful lightening agent that helps to eliminate and fade those unwanted dark marks.

Sun protection is your absolute essential when dealing with hyperpigmentation. You will find the superior sunscreen solutions you need on the Online Skin Care Shop.  

Second line: Getting under your skin

When dealing with post-inflammatory hyperpigmentation on skin that has been physically damaged or inflamed by disorders like acne, you probably need a combined strategy of skincare, peels and/or injectables:

NeoStrata ProSystem Free-Glycolic Peel is a medical system of peels that can only be used under the supervision of an aesthetic doctor.

NeoStrata, pioneers in AHA and the use of glycolic acid, have devised a system of glycolic acid peels that vary in strength from 20% to 70% – the appropriate strength is used to suit your skin. The peel works to thin out the outer most layer of skin and plump up the living layers of the epidermis. This helps even out skin tone and pigmentation and decreases fine lines and wrinkles. It is perfect for all skin tones and skin types, including sensitive skin. Usually a course of four to six peels spaced four weeks apart is recommended to see a clinical result or outcome.

The other option (which can be used alongside peels) is injectables such as Mesotherapy. Used correctly, tiny amounts of active ingredient (in this case pigmentation-busting TA) are delivered directly into the mesoderm (middle layer of skin) by micro injections to target hyperpigmentation. For needle-phobes, transdermal mesotherapy, where the ingredients are pushed in to the skin with current rather than needles, is also an option.

The third line: Bring out the big guns

For severe pigmentation or dermal pigmentation (or if you have superficial pigmentation but no budget restrictions), treatments such as the Platelet Rich Plasma (vampire facial), lasers such as the Fraxel DUAL and lights have the ability to reach the deepest layers of the dermis, addressing pigmentation issues at the deepest levels.

The Fraxel™ DUAL incorporates two lasers in one: the original 1550nm restores wavelength, targets skin texture and improves deep lines and acne scars, while the addition of the 1927 Thulium laser ensures that all forms of pigmentation can be treated. This gentle, FDA-approved treatment resurfaces the skin from the inside out, showing dramatic results in the treatment of sun damage and pigmentation with hardly any downtime. 

Dr. Maureen Allem, founder of Skin Renewal says: “It is quite a challenge to try and sort out all your ageing concerns in the same treatment session, but every so often aesthetic technology leaps ahead and gives us a gem like the Fraxel™ DUAL.”

The two lasers can be used together or separately, and show results in as little as two to three treatments.

Other light therapies that work effectively to treat dark pigmentation marks include: 

Laser Genesis: award-winning, non-invasive light therapy that effectively treats dark marks, uneven texture and blemishes without pain or downtime
Limelight: non-invasive IPL specifically for brown and red marks
Photo Genesis: the super-safe, next-generation IPL photo rejuvenation
Pearl rejuvenation laser: gives you very targeted skin resurfacing, without weeping skin or significant downtime. Suitable for fair to medium-depth complexions.

 

Visit the skin experts at Skin Renewal branches to identify your type of pigmentation and discover your treatment options both in salon and at home. Find out more at www.skinrenewal.co.za and on the Online Skin Shop.

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Health24.com | 7 tips on how to eat out with IBS

Crippling stomach cramps, diarrhoea or constipation and an intolerance to certain foods can turn any dining experience or social event involving food and drinks into a nightmare.

Luckily there are tips to improve your dining experience when suffering from IBS (irritable bowel syndrome).

IBS  is the term used for a spastic colon. According to Health24, the common symptoms of IBS are:

  • Excessive gas 
  • Bloating
  • Pain in the lower abdomen
  • Nausea
  • A change in bowel movements (diarrhoea or constipation), which often brings a sense of relief to abdominal pain

There are several causes of IBS, which can be aggravated by foods containing FODMAPs, an acronym that stands for fermentable oligo-, di-, mono-saccharides and polyols”. This basically means certain foods such as dairy products, legumes and fruit. Not everyone with IBS is FODMAP intolerant, but it is certainly common. To lessen symptoms of IBS, nutritionists advise patients to eliminate FODMAPs from their diet.

1. Plan ahead

If you are invited to a restaurant, research the menu online for meal options. Check out the gluten-free options on the menu. At a steakhouse, it’s easy  to order a wheat-free, dairy-free (which is known to trigger symptoms) options such as a portion of grilled meat with a side of veggies or salad. If you do have special requests, call ahead and explain your dietary preferences. Most restaurants will be happy to adapt a meal for you.

eating out with IBS

iStock

2. Treat the symptoms

If you know what to expect, lessen your symptoms with over-the-counter remedies. If you know you are prone to diarrhoea, have medicine at hand to treat this. That way, you can be prepared if your symptoms appear when you are out. 

Eating out with IBS

3. Steer clear of the sauces

IBS-triggering FODMAPS are often hidden in sauces and condiments. If a portion of meat is marinated, ask the waiter if the chef can prepare your meat without the marinade. Stick to olive oil and lemon juice to add flavour to your salads. 

eat out with IBS

4. Locate the restroom

Scout the venue beforehand to know where the restroom is located. That way, you can relax and know where to go once your stomach starts acting up.

eating out with IBS

5. Drink smart

Alcohol, caffeine and dairy products are the worst culprits for triggering IBS. Stick to drinks you are comfortable with. Drink plenty of water throughout the night to keep the bloat at bay. Although some alcoholic beverages are more likely to trigger IBS than others, people react differently to different beverages. Stick to what you know. 

Eating out with IBS

6. Have an exit strategy

If you know your symptoms will flare up, arrange your own transport or inform your partner so that you can leave the party or event whenever you start feeling uncomfortable. 

eat out with IBS

iStock

7. Focus on the company

Breathe, relax and enjoy the presence of the people surrounding you. Don’t make the event all about the food, but rather focus on the conversation and the company.

Eat out with IBS

Read more:

Beating IBS with the low fodmap diet

Do you suffer from IBS?

IBS changes brain structure

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Health24.com | National Health Insurance approved and gazetted

The National Health Insurance (NHI) white paper will finally be gazetted today (Friday, 30 June 2017) after being approved by Cabinet last week.

Health Minister Aaron Motsoaledi announced on Thursday at a press conference in Pretoria that plans were still under way to use tax credits on medical aids, that add up to R20 billion per year, to fund initial priority areas of the NHI.

Some people will be upset

These priority areas include dental care, spectacles, hearing aids and speech therapists for school-going children who suffer from physical barriers to learning. The Department of Health conducted an audit of about 3.2 million children and found approximately 500 000, disproportionately from poorer schools, suffered from one or more of these barriers.

“We need to massively reorganise the health system… [And this] will upset some,” he said.

He said that tax rebates, given to medical scheme members annually, serve to make the rich even richer and need to be used to assist the poor. He said his office had had negotiations with National Treasury on the earmarking of these rebates since former Finance Minister Pravin Gordhan suggested they be used for the NHI in his February budget speech.

“The ball is now in the Treasury’s court,” said Motsoaledi.

Along with substantive changes to legislation, he said that, under the NHI, teaching hospitals would become more autonomous and report directly to the National Department instead of the current provincial system.

No one will be turned away

Last week he told Health-e News these intuitions are “national treasures” and should be given the power to spend on what they need without having to deal with budget and bureaucratic restrictions.

According to the Health Ministry the NHI is, by definition, a “health financing system that pools funds to provide access to quality health care services to all South Africans, based on their health needs and irrespective of their socio-economic status”.

He said it would function like a big medical scheme, but that it would be different because everyone would have to contribute and no-one could be turned away based on their financial status.

“People in medical aids are stratified. The higher your position is, the higher your salary is, the better health package you are given,” he said. “But that type of system cannot be allowed. Because high blood pressure is high blood pressure [regardless].”

He lamented the fact that 80% of the country’s specialists serve the private sector where only 16 percent of the population have access to care. The state also shoulders the entire tuberculosis treatment and care burden, despite it being South Africa’s number one infectious disease killer.

“Some think we are driven by ideology, but we are driven by simple facts like this,” he said. “It’s wrong and the whole world knows it’s wrong.” – Health-e News.

Read more:

10 NHI facts

Medical scheme tax credit a step towards NHI

NHI reflects global trend

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Ancient South Carolina whale yields secrets to filter feeding’s origins

The blue whale is the largest animal that has ever lived. And yet they feed almost exclusively on tiny crustaceans known as krill. The secret is in the baleen, a complex filter-feeding system that allows the enormous whales to strain huge volumes of saltwater, leaving only krill and other small organisms behind. Now, researchers who have described an extinct relative of baleen whales in Current Biology on June 29 offer new insight into how baleen first evolved.

The findings shed light on a long-standing debate about whether the first baleen whales were toothless suction feeders or toothed whales that used their teeth like a sieve to filter prey out of water, the researchers say. The teeth of the newly discovered species of mysticete, called Coronodon havensteini, lend support to the latter view.

“We know from the fossil record that the ancestors of baleen whales had teeth,” says Jonathan Geisler of the New York Institute of Technology College of Osteopathic Medicine. “However, the transition from teeth to baleen is controversial. Our study indicates that early toothed whales used spaces between their large complex teeth for filtering and that baleen gradually replaced teeth over millions of years.”

The new whale species was found in the early 2000s by a scuba diver in South Carolina’s Wando River. He was looking for shark teeth and found the fossilized whale instead. The whale, which lived some 30 million years ago, was later recognized as a representative of a new transitional species.

“The skull of this species indicates that it split off very early in mysticete whale evolution, and our analyses confirm that evolutionary position,” Geisler says.

Geisler and his colleagues realized that meant the whale could offer important clues about the teeth to baleen transition. The whale under study also had other interesting features. It was larger than other toothed mysticetes, with a skull nearly one meter long. Its large molars in comparison to other whales further suggested an unusual feeding behavior.

Closer examination of the shape and wear on the whale’s teeth led the researchers to conclude that the whale used its front teeth to snag prey. But the whale’s large, back molars were used in filter feeding, by expelling water through open slots between the closed teeth.

“The wear on the molars of this specimen indicates they were not used for shearing food or for biting off chunks of prey,” he says. “It took us quite some time to come to the realization that these large teeth were framing narrow slots for filter feeding.”

As confirmation, the researchers found wear on the hidden cusps bordering those slots between the teeth.

The findings offer another example of a broader evolutionary pattern in which body parts (in this case teeth) that evolved for one function are later co-opted for another function. The researchers say they are now examining closely related species from the Charleston, SC, area in search of additional evidence.

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Materials provided by Cell Press. Note: Content may be edited for style and length.

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Most modern horses are descendants of recently imported Oriental stallions

Researchers who have analyzed the Y chromosomes of more than 50 horses representing 21 breeds have found that the paternal lines of nearly all modern horses trace to stallions brought to Europe from the Orient over the last 700 years. The findings reported in Current Biology on June 29 reveal the overwhelming influence of breeding schemes driven by strong selection on males.

With the genetic genealogies in hand, it’s now possible to elucidate the origin and relationship of any stallion line in detail, the researchers say.

“Apart from stallion lines in Northern European breeds, all stallion lines detected in other modern breeds derive from more recently introduced Oriental ancestors,” says Barbara Wallner at the University of Veterinary Medicine, Vienna. “Our data therefore illuminate the enormous impact modern horse breeding strategies — characterized by strong selection of males and the import of Oriental stallions — during the past few hundred years had on Y chromosome diversity.”

Y chromosomes are passed down from fathers to their sons. This inheritance pattern makes the Y chromosome a good place to look for clues about the unique history of males of a species. In the new study, the researchers focused on a portion of the Y chromosome that is passed down from one generation to another faithfully. Any changes to that portion of the Y chromosome are the result of new mutations.

“Since random mutations accumulate over time, males who originate from a common patrilineal ancestor will share a particular collection of Y chromosome mutations,” Wallner explains, forming what’s known as a haplogroup.

It had been difficult to reconstruct the history of stallions before because there is extremely low diversity in the Y chromosomes of modern horses to start. The researchers got around that problem by using deep, next-generation DNA sequencing, allowing them to pick up on even the smallest changes.

Their analysis of the 52 Y chromosomes showed that the paternal lineages of various modern horses split much more recently than the domestication of the species, which goes back more than 5,000 years. Apart from a few private Northern European haplotypes, all modern horse breeds included in the study clustered into a roughly 700-year-old haplogroup, transmitted to Europe by the import of Oriental stallions, they report. The haplogroup includes two major subgroups (or clades): the Original Arabian lineage from the Arabian Peninsula and the Turkoman horse lineage from the steppes of Central Asia.

By linking the Y chromosome lineages with genealogical information derived from written records, the researchers say it’s now possible to define Y haplotypes for certain founder stallions. Using this approach, they unraveled the origin of English Thoroughbreds, tracing them to Turkoman founder stallions.

“Our results pave the way for a fine-scaled genetic characterization of stallion lines, which should become routine in the near future,” Wallner says.

The researchers say they now plan to create a global Y chromosome phylogeny to include stallion lineages from more rural horses, which most likely lack any recent Oriental influence.

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Materials provided by Cell Press. Note: Content may be edited for style and length.

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Genetic ‘fossils’ reveal long-term viral partnerships in grass

Defective viruses incorporated into grass genomes may adapt to form partnerships with other genome-incorporated viruses in order to complete their life cycle, according to a new PLOS Pathogens study. The findings suggest that partner viruses evolve in concert, enabling them to maintain their relationship over time.

The genomes of animals, plants, and fungi contain stretches of DNA that originated in viruses, integrated into ancient host genomes after infection, and were passed down to host offspring. These viral “fossils” provide an opportunity to study interactions between viruses within host cells on an evolutionary scale.

To better understand viral interactions, Sunlu Chen and colleagues at Hokkaido University, Japan, focused on viral fossils passed down from ancient grasses in the Poaceae grass family. Specifically, they were interested in fossils of viruses known as pararetroviruses (PRVs), which don’t integrate into host DNA as part of their normal life cycle, but may incidentally leave viral “fossil” in host genomes while retaining the ability to complete their life cycle.”

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Evidence suggests that the other two defective PRVs may have developed a mutualistic partnership, with each species providing complementary protein machinery lacked by the other species.

The research team found that the two species in each partnership have frequently exchanged DNA stretches called noncoding regulatory sequences (NRSs) with each other over time. This concerted evolution has resulted in the partnered species sharing highly similar NRSs, and it appears to have enabled development and maintenance of the partnerships over time.

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Materials provided by PLOS. Note: Content may be edited for style and length.

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