A small study in South Africa suggests the new variant could partially evade the Pfizer jab.
Category Archives: Body Optimization
Covid booster jab booking system opens to over-40s in England
Another seven million people will be able to book their top up jab, including those in at-risk groups.
Covid: Early signs Omicron spreads more easily, says No 10
But PM’s spokesman says exact impact is yet to be determined, as UK cases of the variant reach 437.
I’m A 40-Something Woman With Wrinkles And Cellulite — And I’ve Stopped Trying To Hide It

It’s shortly after my 40th birthday, I’m enjoying some well-deserved time off with my family, and it’s shaping up to be one of the loveliest days I’ve had in a long time. We’d spent the day out in the water, and everyone was still lounging around in their swimwear by the time dinner rolled around.
At some point, the conversation turned to fitness. After years of yo-yo diets, watching what I ate, and berating myself with all types of internal verbal abuse, I was finally in a healthy space — mentally and physically. I was in a hot pink bikini, and I felt fly and fabulous. To celebrate and acknowledge that, I happily shared how I was feeling with my family: “I’m in the best shape of my life.”
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Ten words were all it took to shatter the moment.
“That’s not true,” my brother scoffed. “I saw the cellulite on your legs.”
My face flushed immediately. My stomach dropped and the air rushed out of me. I was shocked. Then embarrassed. And then furious. His wife immediately called him out on making such an insensitive, backward and rude comment.
I simmered in anger but I also felt bad. Bad that my sister-in-law was arguing on my behalf. Bad that everyone in my family had heard my brother’s comment. Bad that my kids had to witness this ugliness.
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My first instinct was to brush it off and manage everyone’s emotions so we could still salvage the evening. Fifteen years ago, Susan would have left it at that. But 40-year-old Susan? She was tired of constantly shouldering the invisible workload of women.
I shut my brother down. “Yeah, I’m celluLIT,” I responded before telling him that cellulite has zero to do with my fitness level or whether I deserve to feel good about myself. I’d been fighting body image issues for years, and my insecurities with aging were nothing new to me, but I was going to be damned if I let my kids grow up thinking that having cellulite or wrinkles was bad.
When I was a kid, I was no stranger to worrying about aging. I remember watching my mother stand in front of a mirror, nitpicking at her appearance as she noticed her skin sagging or wrinkling. I’d tell her she was beautiful.
“You won’t understand until it happens to you,” she would say. And oh, how right she was.
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When I turned 38, I started noticing the first signs of perimenopause. Suddenly, I had to adjust my lifestyle. The way I ate and what I drank. And just as suddenly, I started noticing changes in my body. My skin sagging where it didn’t use to sag. Wrinkles appearing and deepening where they didn’t use to be.
Goodbye luscious hair, supple skin and strong bones, I thought to myself bitterly as I looked in the mirror, flashing back to the moments my mother would do the same.
But it wasn’t just my mother who hammered in these insecurities. There’s a $58.5 billion anti-aging industry that’s making bank off these thoughts.
You don’t want to be old, says every anti-aging cream. You want to be wrinkle-free, like me, says every airbrushed model image. You want to be desirable, says society.
Last year, a meme comparing Jennifer Lopez and Rue McClanahan from ”Golden Girls” went viral. Both aged 50, there was Rue in an old-fashioned maternal look versus J-Lo, dressed in a sheer and sequin costume, hanging off a pole at the Super Bowl.
Seeing that meme made me angry. Angry that we choose to celebrate women for their ability to look young rather than something more concrete. Angry that we continue to pit women against each other as well, over something as natural and uncontrollable as aging.
“I am no longer happy in spite of my aging body. I am thrilled to see my body evolve — just as it’s supposed to.”
Between the ages of 38 and 40, I comforted myself by focusing on aging gracefully. I’ll be different. I won’t worry over my changing looks, I’ll embrace them and wear them with grace. But the aging part was still happening, graceful or not. And I still found myself scrutinizing my insecurities in front of the mirror as my mother had before me.
I thought aging was wrong because the media spent my entire life telling me so. Because society erases women over a certain age. Because actresses are airbrushed and Botox-ed while actors are called “mature” and ”stately” with their wrinkles. Because there is no space where an aging woman is shown in a positive light.
But you take away my age, and I am still a business owner, a badass entrepreneur who coaches women to their success. A lively, vibrant person. A friend. A mother. A partner.
I pushed myself to be mindful in the moments these insecurities would threaten to take over. I challenged myself to remember that I was fed this BS about aging. It wasn’t the truth.
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I took a hard look at what I surrounded myself with online and started curating my space with content that would lift me up rather than minimize me. And as the male gaze began to shift off of me, I found it liberating to no longer be subject to society’s expectation of desirability or be boiled down to my reproductive value. This freedom started to incite a sense of newfound independence.
Worrying about aging, I soon realized, was stealing my youth. I was losing time, money, confidence and energy to it. Why hide my cellulite and stretch marks? My saggy skin and wrinkles? My body has carried me my whole life and the way it looks is my business.
Choosing to accept aging for what it is — a natural part of life — is one of the most empowering things we can do as women. In my refusal to let societal expectations push me aside, I found myself becoming bolder and louder and prouder. Clapping back instead of sitting in silence. Standing up for myself and my beliefs instead of meekly muttering excuses.
Since I have started mindfully rejecting the aging industry, my internalized ageism has melted away. I am no longer happy in spite of my aging body. I am thrilled to see my body evolve — just as it’s supposed to.
I still have moments of insecurity. Moments when I find myself in front of a mirror, staring a little too hard. But I choose to extend the same compassion I would extend to anyone else. I remind myself of the person I am, of the life I have lived, and the surety that there is still so much more to see, live and experience.
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Drugs plan aims to help 300,000 problem drug users
A new drugs strategy will mean more funding for treatment and a crackdown on gangs, ministers say.
New type of earthquake discovered

A Canadian-German research team have documented a new type of earthquake in an injection environment in British Columbia, Canada. Unlike conventional earthquakes of the same magnitude, they are slower and last longer. The events are a new type of induced earthquake that have been triggered by hydraulic fracturing, a method used in western Canada for oil and gas extraction. With a network of eight seismic stations surrounding an injection well at distances of a few kilometres, researchers from the Geological Survey of Canada, Ruhr-Universität Bochum, and McGill University recorded seismic data of approximately 350 earthquakes. Around ten percent of the located earthquakes turned out to exhibit unique features suggesting that they rupture more slowly, similar to what has previously been observed mainly in volcanic areas.
The group headed by Hongyu Yu – first at RUB, later at the Canadian Geological Survey of Canada – and RUB Professor Rebecca Harrington describes the results in the journal Nature Communications, published online on 25 November 2021.
Several theories on the origins of earthquakes
To date, researchers have explained the occurrence of earthquakes in the hydraulic-fracturing process with two processes. The first says that the fluid pumped into the rock generates a pressure increase substantial enough to generate a new network of fractures in the subsurface rocks near the well. As a result, the pressure increase can be large enough to unclamp existing faults and trigger an earthquake. According to the second process, the fluid pressure increase from injection in the subsurface also exerts elastic stress changes on the surrounding rocks that can be transmitted over longer distances. If the stress changes occur in rocks where faults exist, it can also lead to changes that cause the fault to slip and cause an earthquake.
Recently, numerical models and lab analyses have predicted a process on faults near injection wells that has been observed elsewhere on tectonic faults. The process, termed aseismic slip, starts out as slow slip that does not release any seismic energy. The slow slip can also cause a stress change on nearby faults that causes them slip rapidly and lead to an earthquake. The lack of seismic energy from aseismic slip and the size of the faults involved make it difficult to observe in nature. Researchers have therefore not yet been able to document aseismic slip broadly with any association to induced earthquakes. The work of the current study, provides indirect evidence of aseismic loading, and a transition from aseismic to seismic slip.
Modifying the hydraulic fracturing process
The German-Canadian research team interpret the recently discovered slow earthquakes as an intermediate form of conventional earthquake and aseismic slip – and thus as indirect evidence that aseismic slip can also occur in the vicinity of wells. The researchers therefore dubbed the events hybrid-frequency waveform earthquakes (EHW).
“If we understand at which point the subsurface reacts to the hydraulic-fracturing process with movements that don’t result in an earthquake and, consequently, cause no damage to the surface, ideally we could use that information to adjust the injection procedure accordingly,” as Rebecca Harrington, Head of the Hydrogeomechanics Group at RUB, describes one implication of the study.
Not all quakes spread at the same rate
“We’d assumed that induced earthquakes behave like most other earthquakes and have roughly the same rupture speed of two to three kilometres per second,” explains Rebecca Harrington. But that doesn’t always seem to be the case. While the shaking from a conventional earthquake of magnitude 1.5 in the researchers’ data set had died down after about seven seconds, an EHW earthquake of the same magnitude continued to shake for more than ten seconds.
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Materials provided by Ruhr-University Bochum. Note: Content may be edited for style and length.
Too dry, too hot, or too wet: Increasing weather persistence in European summer

“In our study, we show that persistent weather conditions have an increasing similarity in summer over the North Atlantic, Europe and Siberia, favoring more pronounced extreme weather events. In Europe alone, about 70% of the land area is already affected by more persistent weather situations,” says Peter Hoffmann from the Potsdam-Institute for Climate Impact Research (PIK), lead author of the study published in Nature scientific reports. “This means that people, especially in densely populated Europe, will likely experience more and also stronger and more dangerous weather events.”
Prolonged sunny or rainy conditions lead to extreme events
To prove this, the scientists analysed the persistence of specific weather conditions. They applied established image comparison methods on atmospheric data, comparing millions of successive weather circulation patterns worldwide over the last 40 years. They especially looked at two individual extreme events, the 2010 heat wave over Russia and the extraordinary dry summer over Europe in 2018. “We found that weather patterns in general are more persistent now than some decades ago,” says Hoffmann. “Especially in summer, heat waves often last longer now, and also rainfall events tend to linger longer and to be more intense. The longer these weather conditions last, the more intense the extremes can become, both on the warm and dry side as well as on the steady rain side.”
The rise in persistent weather conditions is to a large extent due to dynamical changes in the atmosphere as the westerly winds tend to stop pushing forward weather systems which therefore become more persistent, turning some sunny days into heatwaves of several weeks as well as intensive rainfall into floods.
Climate models might underestimate rise in persistent weather patterns
Like the eye of a knowledgeable observer, the new image comparison method systematically scans atmospheric fields and helps to assess to which extent successive weather circulation patterns change over time or remain stable. Fred Hattermann, co-author of the study and also scientist at PIK, explains the potential of the new approach: “Our method crucially improves the interpretation of long-term climate impacts. When applying the same methodology to climate model output, we do not see a comparable increase in weather persistence, especially not over Europe. Climate models may have been a bit too conservative, underestimating the rise in weather persistence — thus underestimating weather extremes over Europe.” This becomes ever more important with ongoing climate change.
“Recent events and ongoing research have shown that the number and intensity of extreme events have increased due to the global rise in temperature,” concludes Hattermann. “To counteract this worrying trend, the goal has to be to reduce global greenhouse gas emissions and by doing so limit climate change.”
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Materials provided by Potsdam Institute for Climate Impact Research (PIK). Note: Content may be edited for style and length.
Researchers crack the synthetic code of rare molecules sought after in drug development

A research team at Lund University in Sweden has succeeded in producing two molecules that are otherwise only formed by microorganisms from extremely contaminated wastewater in an abandoned mine in South Korea. The method, which took four years to develop, could pave the way for new types of drugs. The study is published in Journal of the American Chemical Society.
Glionitrin A and B are two molecules with properties that make them useful in drug development. However, researchers who want to use these molecules have faced an uphill battle for almost a decade.
Glionitrin A and B are natural products, and are produced a fungus found in extremely contaminated acidic wastewater from an abandoned South Korean mine. Since the fungus only creates the molecules when triggered by specific bacteria from the same sewage, it has proved difficult to produce .
“We have been working on this problem for four years. Every time we thought we had a solution, the molecules revealed unexpected properties that sent us back to the drawing board,” says Daniel Strand, chemistry researcher at Lund University.
Despite the complex nature of the problem, the solution proved to be both simpler and more effective than the researchers thought. By developing a new so-called asymmetric organocatalytic reaction, Daniel Strand and his colleagues succeeded in the most inaccessible parts of the molecules.
“we thought the problem was solved, the molecule had one last surprise. It turned out that the real structure was the mirror image of we initially thought was glionitrin A. So, all this time we had chased a molecule that ,” says Daniel Strand.
Complex natural products with unique properties such as glionitrin A and B are important tools in develop.
Glionitrin A has shown antibiotic properties against resistant bacteria, while glionitrin B makes cancer cells less to migrate. Being able to produce the molecules synthetically helps researchers not only understand how they work, but also improve their properties.
“There is a great need for new types of antibiotics, especially those that can contribute to the fight against resistant bacteria. We expect our results to inspire further development basic synthetic chemistry but also to be used in drug development,” concludes Daniel Strand.
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Materials provided by Lund University. Note: Content may be edited for style and length.
Viagra may be useful against Alzheimer’s dementia
The impotence pill could have effects in the brain that may help fight dementia, say US researchers.
