BBC research shows one-in-three new doctors in England last year came from outside the UK and EU.
Category Archives: Body Optimization
Did we all believe a myth about depression?
A study some claim debunks antidepressants has gone viral. Was it read wrong?
Chrissy Teigen and John Legend announce pregnancy
The US model says she and John Legend are expecting a baby, nearly two years after a stillbirth.
Afra Rafeeq: India teen who died but raised millions to save her brother
Afra Rafeeq, who died this week, had raised millions of rupees to help get a crucial drug for her baby brother.
Highest coral cover in central, northern Reef in 36 years

The northern and central Great Barrier Reef have recorded their highest amount of coral cover since the Australian Institute of Marine Science (AIMS) began monitoring 36 years ago.
Published today, AIMS’ Annual Summary Report on Coral Reef Condition for 2021/22 shows another year of increased coral cover across much of the Reef.
In the 87 representative reefs surveyed between August 2021 and May 2022 under the AIMS Long-Term Monitoring Program (LTMP), average hard coral cover in the region north of Cooktown increased to 36% (from 27% in 2021) and to 33% in the central Great Barrier Reef (from 26% in 2021).
However, average coral cover in the southern region (from Proserpine to Gladstone) decreased from 38% in 2021 to 34%.
AIMS CEO Dr Paul Hardisty said the results in the north and central regions were a sign the Reef could still recover, but the loss of coral cover in the southern region showed how dynamic the Reef was.
“A third of the gain in coral cover we recorded in the south in 2020/21 was lost last year due to ongoing crown-of-thorns starfish outbreaks,” he said.
“This shows how vulnerable the Reef is to the continued acute and severe disturbances that are occurring more often and are longer-lasting.”
Dr Hardisty said the increased frequency of mass coral bleaching events was “uncharted territory” for the Reef, with this year’s bleaching event the fourth in seven years and the first to occur during a La Niña.
“In our 36 years of monitoring the condition of the Great Barrier Reef we have not seen bleaching events so close together,” he said.
“Every summer the Reef is at risk of temperature stress, bleaching and potentially mortality and our understanding of how the ecosystem responds to that is still developing.
“The 2020 and 2022 bleaching events, while extensive, didn’t reach the intensity of the 2016 and 2017 events and, as a result, we have seen less mortality. These latest results demonstrate the Reef can still recover in periods free of intense disturbances.”
AIMS monitoring program team leader Dr Mike Emslie said the 2022 results built on the increases in coral cover reported for 2021, with most of the increase continuing to be driven by fast-growing Acropora corals.
“These corals are particularly vulnerable to wave damage, like that generated by strong winds and tropical cyclones,” he said.
“They are also highly susceptible to coral bleaching, when water temperatures reach elevated levels, and are the preferred prey for crown-of-thorns starfish. This means that large increases in hard coral cover can quickly be negated by disturbances on reefs where Acropora corals predominate.”
Dr Emslie said climate change was driving increasingly frequent and longer-lasting marine heatwaves.
“The peak of the most recent bleaching event in March occurred when the accumulated heat stress caused widespread bleaching but not extensive mortality,” he said.
“The increasing frequency of warming ocean temperatures and the extent of mass bleaching events highlights the critical threat climate change poses to all reefs, particularly while crown-of-thorns starfish outbreaks and tropical cyclones are also occurring. Future disturbance can reverse the observed recovery in a short amount of time.”
Background
The 36-year-long dataset of AIMS’ Long-Term Monitoring Program (LTMP) is the largest, longest, and most comprehensive information source on the health of the Great Barrier Reef. It helps determine long-term trends in the condition of coral communities across the Reef.
Percent hard coral cover describes the proportion of the reef that is covered in living hard coral. In 2021-22, most reefs surveyed had between 10 and 50 percent.
Bleaching is a coral’s response to stressful conditions such as heat. During bleaching, the coral animal loses its symbiotic algae and pigments, causing it to turn white and potentially die. Corals can survive a bleaching event, but they are under more stress.
Report; https://www.aims.gov.au/monitoring-great-barrier-reef/gbr-condition-summary-2021-22
New patent-pending method mass-produces antitumor cells to treat blood diseases and cancer

A Purdue University chemical engineer has improved upon traditional methods to produce off-the-shelf human immune cells that show strong antitumor activity, according to a paper published in the peer-reviewed journal Cell Reports.
Xiaoping Bao, a Purdue University assistant professor from the Davidson School of Chemical Engineering, said CAR-neutrophils, or chimeric antigen receptor neutrophils, and engraftable HSCs, or hematopoietic stem cells, are effective types of therapies for blood diseases and cancer. Neutrophils are the most abundant white cell blood type and effectively cross physiological barriers to infiltrate solid tumors. HSCs are specific progenitor cells that will replenish all blood lineages, including neutrophils, throughout life.
“These cells are not readily available for broad clinical or research use because of the difficulty to expand ex vivo to a sufficient number required for infusion after isolation from donors,” Bao said. “Primary neutrophils especially are resistant to genetic modification and have a short half-life.”
Bao has developed a patent-pending method to mass-produce CAR-neutrophils from human pluripotent stem cells (hPSCs), that is, cells that self-renew and are able to become any type of human cell. The chimeric antigen receptor constructs were engineered to express on the surface of the hPSCs, which were directed into functional CAR-neutrophils through a novel, chemically defined protocol.
The method was created in collaboration with Qing Deng at Purdue’s Department of Biological Sciences, Hal E. Broxmeyer, now deceased, at Indiana University School of Medicine, and Xiaojun Lian at the Pennsylvania State University.
“We developed a robust protocol for massive production of de novo neutrophils from human pluripotent stem cells,” Bao said. “These hPSC-derived neutrophils displayed superior and specific antitumor activities against glioblastoma after engineering with chimeric antigen receptors.”
Bao disclosed the innovation to the Purdue Research Foundation Office of Technology Commercialization, which has applied for an international patent under the Patent Cooperation Treaty system of the World Intellectual Property Organization. The innovation has been optioned to an Indiana-headquartered life sciences company.
“We will also work with Dr. Timothy Bentley, professor of neurology and neurosurgery,and his team at the Purdue College of Veterinary Medicine to run clinical trials in pet dogs with spontaneous glioma,” Bao said.
This research project was partially supported by the Davidson School of Chemical Engineering and College of Engineering Startup Funds, Purdue Center for Cancer Research, Showalter Research Trust and federal grants from the National Science Foundation and National Institute of General Medical Sciences.
Story Source:
Materials provided by Purdue University. Original written by Steve Martin. Note: Content may be edited for style and length.
As reflective satellites fill the skies, students are making sure astronomers can adapt

As satellites crawl across the sky, they reflect light from the sun back down to Earth, especially during the first few hours after sunset and the first few hours before sunrise. As more companies launch networks of satellites into low-Earth orbit, a clear view of the night sky is becoming rarer. Astronomers, in particular, are trying to find ways to adapt.
With that in mind, a team of University of Arizona students and faculty completed a comprehensive study to track and characterize the brightness of satellites, using a ground-based sensor they developed to measure satellites’ brightness, speed and paths through the sky. Their work could be helpful for astronomers, who, if notified of incoming bright satellites, could close the shutters of their telescope-mounted cameras to prevent light trails from tainting their long-exposure astronomical images.
The research team was led by professor of planetary sciences Vishnu Reddy, who also co-leads — with professor of systems and industrial engineering Roberto Furfaro — the university’s Space Domain Awareness lab, which tracks and characterizes all kinds of objects orbiting Earth and the moon.
Grace Halferty, a senior graduating this summer with a bachelor’s degree in aerospace and mechanical engineering, is the lead author of the study, which is published in Monthly Notices of the Royal Astronomical Society. The study details how the team created a satellite tracking device to measure the brightness and position of SpaceX Starlink satellites and compared those observations to government satellite tracking data from the Space Track Catalog database.
“Until now, most photometric — or brightness — observations that were available were done by naked eye,” Halferty said. “This is one of the first comprehensive photometric studies out there to go through peer review. The satellites are challenging to track with traditional astronomical telescopes, because they are so bright and fast-moving, so we built what’s basically a small sensor with a camera lens ourselves because there was nothing off the shelf available.”
The team made 353 measurements of 61 satellites over two years and found that the position of Starlink satellites as recorded in the government’s Space Track Catalog only differed by an average of 0.3 arc seconds from the UArizona calculations. An arc second on the sky is about the size of a dime held 2.5 miles away. The tiny difference is probably due to natural lag times in the government data, Reddy said. Because that data is based on estimated orbits calculated days earlier, rather than on real-time observations, positioning errors can build up.
“This suggests that there is hope that astronomers can use these data to close the shutter of their telescopes in time amid the growing chaos in the skies above,” Reddy said.
A stellar traffic jam
Starlink is a large network of satellites, also called a mega constellation, operated by SpaceX with the goal of providing global internet coverage. SpaceX started launching Starlink satellites in 2019. Today, more than 2,700 Starlink satellites have launched — a fraction of the intended total of 42,000 satellites.
Other examples of satellite constellations include 31 GPS satellites and 75 iridium satellites for communication. Other entities have plans to launch more satellites into low and medium Earth orbit in the next few years. Amazon, for example, plans to launch 3,000 satellites, and the Chinese government plans to launch 13,000. These satellites will orbit no higher than 22,000 miles above Earth.
The problem with satellites is that they require power harvested from solar panels, which can reflect sunlight at ground-based telescopes and, in turn, impact astronomical observations from telescopes around the world. About 30% of all telescope images will be impacted by at least one satellite trail once the Starlink constellation is complete, said research team member Tanner Campbell, a graduate research assistant in the Department of Aerospace and Mechanical Engineering.
“As other constellations are added, the problem will only get worse for ground-based astronomical surveys,” he said.
These satellites are even more reflective right after launch, while they are still relatively low and tightly clustered before they spread throughout their orbit over time. They are often as bright as Saturn or Jupiter, two of the brightest objects in the night sky. As they maneuver into higher orbits, they become slightly fainter.
A moving target
SpaceX has deployed a few different methods to darken its Starlink satellites. For example, VisorSat satellites rely on a shade to block additional sunlight, making them 1.6 times fainter. DarkSat satellites, on the other hand, rely on an anti-reflective coating that makes them 4.8 times fainter. However, DarkSats got too hot, so SpaceX moved away from that specific method. Since August 2021, all Starlink satellites are VisorSats.
“While these modifications are steps in the right direction, they also don’t dim the satellites enough for astronomical surveys,” said research team member Adam Battle, a graduate student studying planetary science.
In July, SpaceX announced new strategies. One involves mirrors that reflect sunlight away from Earth and another involves using darker building materials. Reddy’s team plans to study how effective these methods are at reducing sunlight reflection back to Earth.
While knowing exactly where satellites are is helpful to astronomers, the act of shutting the cameras adds overhead costs for telescope operations. Surveys become less efficient when astronomers have to close the shutter or throw away contaminated images. For example, a survey that would take five years to complete could take 10% to 20% more time if survey efficiency is down. Costs will continue to increase as more satellites are launched, Reddy said.
The team plans to build upon its success by studying the brightness of the latest generation of Starlink satellites in four different colored filters — the same ones used in astronomical surveys of the sky to tease out different information from stars, planets and more. To achieve this, the team has worked with Tucson-based small business Starizona to build a sensor that can take pictures of satellites in four colors simultaneously.
“Working with local small businesses is a win for us as it provides our students an opportunity to rapidly prototype and bring a new system online,” Reddy said.
Junior doctors’ pay offer concerns hospital leaders
The morale of junior doctors will be damaged by a lower pay rise than other staff, hospitals in England say.
How to Win Against Your Favorite Distractions
What can you do when you realize that you’ve been wasting a lot of time succumbing to distractions, like endless social media or consumption-based activities, and it’s making you feel empty, hollow, disappointed, or even ashamed of yourself? How can you reboot and get your life (and your character development) back on track?
A key here is to raise your awareness of how this behavior pattern is punishing you and what you’re missing out on. And that’s the truth – you’re missing out on tons that life has to offer when you stick with the low-hanging fruit of repetitive but unfulfilling actions.
One way I like to do this is to maintain a clear line of sight to goals that are compelling. The goals have to be a lot more fascinating and stimulating than the distractions, and my goals need to provide emotional endurance that won’t easily fade. Otherwise the distractions will win. Limp goals won’t work.
Keeping long-term goals in our awareness requires a lot of refreshing. For many people this means looking at our goals and thinking about them every day or even multiple times per day. That’s a good test to see if the goals remain interesting or compelling or if they only look good on paper but don’t actually motivate action consistently.
I like to engage with my goals every day, and I’m constantly tweaking, refactoring, and refreshing them to keep them aligned with strong and persistent motivation. When I feel a goal becoming too mental and not thrilling enough, I know it’s dying and that I won’t likely achieve it till I pull it back into the emotional space. This is where reframing skills are a godsend.
Then comes the realization that with enough action and persistence and learning from mistakes, those goals can actually be achieved. Those experiences can be had. Are they better than Facebooking and video games? If not then the goals are no good and ought to be changed because those services are competing for your attention these days.
The future will introduce even more compelling distraction invitations, so your future goals will need to be even more competitive with those other services. If your goals can’t even out-compete today’s offers, you’re really have no chance in the years ahead. So you’d better learn how to pull ahead – and stay ahead – of those distractions today.
For some this may seem disheartening. I actually see it as exciting though. Why is reality providing so much temptation? Is it to pull you away from your goals and make you feel like a loser? No! It’s to invite you to up your goal-setting game. Stop setting such bland and wimpy goals. Set goals that scare you, that will radically transform your life, that will sculpt your character beautifully. Leap into spaces that you’re never explored before.
Most importantly, your goals must be personal. You can’t just rip them off from other people and expect them to have much motivating power. My best goals feel like goals that no one would set but me because they fit me and my personality in such a unique way. If your goals are generic and other people could just as easily set them, they probably won’t motivate you consistently.
A good goal is like a personal mission. It’s for you and you alone. Even if a goal involves a team project, your contribution is uniquely personal. A good goal dives deep into your private space of personal meaning. It’s part of your story, not someone else’s.
So please please please dump those lame-ass goals that you could read anywhere else online, like the ones to lose weight, make a certain amount of money, etc. Video games provide way more compelling goals than those.
You can still do some of those distracting activities for variety if you truly value them. Rachelle and I love watching TV shows and movies together, and sometimes we play video games. But those are filler activities around other goals, and they do provide value in a way that doesn’t feel empty or hollow. I often find inspiration in fictional worlds. I probably wouldn’t even be doing what I’m doing today if not for Star Trek, for instance, since that inspired many of my lifestyle decisions. Watching certain shows together is a fun bonding experience for us too; we often discuss them afterwards, even pausing to discuss while we watch.
I don’t have Facebook, Instagram, Twitter, or many other social media accounts since I don’t feel those services add enough value to my life today. I did find it interesting to explore them, but not to the extent of having them pull me away from more interesting goals. I do have Netflix, Apple TV+, Audible, YouTube, and other accounts that I appreciate. This is guilt-free. This kind of engagement actually builds enthusiasm for other goals if done right.
A good question to ask is: Would I appreciate having this account for another year (or five)? If not, that’s a good reason to cancel it.
When you compare your goals to your distractions, do your goals rise above your distractions enough that you’re going to feel a sting if you don’t work on your goals for a month or so? Do your goals compel you to take action? Do you find it necessary to put off non-goal actions, so you can advance your goals?
It’s one thing to feel disappointed if you wasting some of your life spinning in circles, but that isn’t enough by itself. It’s vital to be aware of what specifically you’re sacrificing if you don’t invest in something more meaningful. With a vague feeling of disappointment, going back to the distractions will remain the go-to treatment.
With a more specific feeling of disappointment where you develop high awareness of the progress you could have made but didn’t, it will be harder to return to distractions and not work on your goals. You’ll see that you’re delaying experiences that matter to you. You’ll see that you’re holding your character back from what you could become. You’ll see more of the specifics that you’re missing.
Your challenge is to create a vision of how you want your life to be, and then keep evolving that vision to make it personal, meaningful, and incredibly compelling. Arnold Schwarzenegger used to put up pics of bodybuilders on his bedroom wall, so he’d stay connected to the vision of how he wanted his body to be. While other people inspired him, he evolved those socially inherited goals into his own personal vision that mattered to him, and he infused a lot of his own personality into his goals. When he tried to pursue goals that other people set for him, like while he was in the military in Austria, he failed miserably.
I really love setting and achieving interesting goals. It’s hard as hell sometimes, and there are occasional setbacks to deal with, but in the long run that just makes the journey more rewarding. I especially love the long-term character sculpting effects. Even for goals I didn’t achieve (or that took longer than I expected), I still appreciate the character gains. I love the creative challenge of figuring out what to do next with my life.
When your goals become compelling enough, distractions become boring by comparison. You can still engage with side hobbies and entertainment if you want – I definitely do – but let those pursuits serve the big picture of where you want to take your life and character. I love the added stimulation and inspiration that comes from a variety of input, but if I overdo that, I’m really going to feel the sting of not making progress on my goals. I’ll be very aware of what else I’m not experiencing.
You have a lot of power to sculpt your experience of life. You can let other people direct your experience, and that’s okay for a while, but the long-term invitation is to do your own conscious sculpting and directing. I really enjoy helping people with those efforts since it’s so rewarding to see people take charge of their lives and create the kinds of experiences they truly appreciate.
Mutual appreciation is what this game is all about. Consider that even those services that you denigrate as distractions were probably created by people who hoped you’d appreciate their efforts. What you call a distraction was someone else’s life’s work. I like this framing because it helps me see that when I’m ready to let go of a service that has run its course for me, I can let go with some appreciation and respect for the value it did provide. I can even thank those services for how they helped me discover what other kinds of experiences I really want to have.
So realize that your distractions are actually trying to help you. If your distractions are more compelling than your goals, look to your distractions for insights about how you could set goals that are more engaging and meaningful for you. Clarify what you don’t like about those distractions, and challenge yourself to design experiences that are better than what they offer. If you can’t beat what those services provide, then you know you have more to learn about how to consciously create better experiences. And then you can actually engage with those services on that basis. You can use them as learning tools and stepping stones to discover how to set better goals and to create better experiences.
Pig organs partially revived hour after death
Study could transform access to organs for transplant by reversing some of the damage caused after death.
