Small period changes after Covid jab seen to be short-lived

Studies confirm cycles quickly return to normal, a leading reproductive expert in the UK says.

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How to ruin the taste of a cookie with just two words

A rose by any other name may smell as sweet, but a chocolate chip cookie labeled “consumer complaint” won’t taste as good as the exact same product described as “new and improved,” a new study suggests.

Researchers labeled identical saltine crackers and chocolate chip cookies as either “new and improved,” “factory typical” or “consumer complaint” for the study, and then asked participants to taste the food samples and judge each on likability, freshness and a range of other qualities.

The crackers and cookies labeled “consumer complaint” received significantly lower overall liking ratings than the samples labeled “new and improved.” This held true for both saltines — a neutral example — and the cookies, which the researchers considered an inherently positive food.

“We had both negative and positive bias — but the negative bias was much bigger. That negative context had more impact than saying ‘new and improved’ had on generating better ratings,” said Christopher Simons, associate professor of food science and technology at The Ohio State University and senior author of the study.

“On one hand, it’s not surprising. On the other hand, the degree of the impact was really surprising.”

The research is published in the journal Food Quality and Preference.

An estimated 70 to 80% of new food products fail, even when consumer testing has suggested they should be successful, Simons said — which is a sign that the methods used to gauge potential customer support might need an upgrade.

“One thing my lab’s really interested in is trying to better understand and be able to predict consumer behavior,” he said. “Currently, companies use humans as an instrument to better understand the sensory properties of foods and how they drive liking. We’re trying to understand our instrument so we can build a better one that may help reduce product failures and help companies deliver products that people actually want.”

The study tested the impact of food labeling on the human predisposition to find negative experiences more significant and memorable, but also underscored the tendency for people to be skeptical of claims that a product is better just because it’s labeled “new and improved.”

The researchers recruited 120 participants aged 18 to 70 from a database of panelists from Ohio State’s Sensory Evaluation Center. Samples of two crackers or cookies — from the same packaging sleeve — were placed on three plates. Researchers told participants they would be evaluating a major supplier’s current typical factory sample, a new and improved prototype and a sample that had received customer complaints.

After each bite, participants indicated their overall liking of the sample on a 9-point scale from “dislike extremely” to “like extremely.” They also completed additional ratings of positive and negative attributes that assessed, for example, how crisp and fresh the crackers were and the intensity of the cookies’ flavor.

The results showed a clear influence of the labeling on consumer perception. With both foods, the overall liking scores were significantly lower for samples labeled “consumer complaint” compared to “new and improved.” With the saltines, the complaint scores were also significantly lower than ratings for the crackers labeled “factory typical.”

In addition, participants generally gave the “consumer complaint” crackers and cookies fewer marks for positive qualities and more hits for negative attributes.

“With the negative contextualized messaging, there were more negative attributes selected — people didn’t like it as much, it wasn’t as fresh. People had a more negative opinion of it,” Simons said. “The positive messaging slanted toward being more positive, but not nearly as much.”

There could be a lesson here for product developers, Simons said. Rather than optimizing positive attributes for a new product idea, perhaps there would be value in teasing out what customers perceive as negative and adjusting accordingly.

“If people are more sensitive to those taints, we can use it to our advantage as it relates to food,” he said. “You get a bigger bang for your buck by removing things people find negative than you do by optimizing those positive attributes. Take care of the negatives first and you’re probably going to have a more successful product.”

This work was supported by the U.S. Department of Agriculture National Institute of Food and Agriculture.

Co-authors, all from Ohio State, include Maria Cotter, Morgan Whitecotton and Devin Peterson.

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Materials provided by Ohio State University. Original written by Emily Caldwell. Note: Content may be edited for style and length.

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‘Smart saddle’ could help equestrians hit their stride

Skilled equestrians make advanced riding maneuvers, like jumps, spins and piaffes, look effortless. But good riding requires balance and subtle cues to the horse, many of which are given through the rider’s posture, seat and legs. Now, researchers reporting in ACS Nano developed a prototype “smart saddle” that could help equestrians improve their biomechanics. Moreover, the self-powered saddle can alert others when a rider takes a fall.

Big data collection and analysis are becoming important components of many competitive sports because they provide real-time information on athletes’ performance and fitness. However, most systems are powered by batteries, often making them bulky and inflexible. In contrast, small, lightweight triboelectric nanogenerators (TENGs), which convert mechanical energy into electricity, are being tested for a variety of applications, from harvesting the energy of ocean waves to charging cell phones through walking. In addition to powering themselves, TENGs can convert mechanical stimuli, such as pressure, touch or motion, into electrical signals. Ding Nan, Baodong Chen, Zhong Lin Wang and colleagues wanted to adapt TENGs to a smart saddle for challenging and potentially dangerous equestrian sports.

The researchers made a thin, flexible, disk-shaped TENG that flattens when depressed and then rebounds when the pressure is removed. Under pressure, the internal layers of the TENG compress, transferring electrons from one electrode to another and generating a current, which stops when the pressure is released.

The team placed an array of seven TENGs on the top surface of a saddle so they could detect differences in pressure in various regions of the seat. Electrical signals from the array revealed whether a rider was leaning forward, sitting in an upright position or leaning backward. The smart saddle also detected when a person was standing up and sitting down (a motion called “posting” in the equestrian world). When a rider falls off, the system can transmit a wireless signal to alert others, a safety feature that could allow an injured rider to be quickly found and treated, which is especially important when riding alone. The self-powered smart saddle, which has a response time of 16 milliseconds, could someday provide real-time statistical data and fall detection to equestrians and their coaches, the researchers say.

The authors acknowledge funding from the Natural Science Foundation of Beijing Municipality, the National Natural Science Foundation of China, the National Key R&D Project from Ministry of Science and Technology, the Beijing Municipal Science and Technology Commission, the Inner Mongolia scientific and technological achievements transformation project and the Inner Mongolia autonomous region major science and technology program.

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Materials provided by American Chemical Society. Note: Content may be edited for style and length.

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A bioelectronic tongue ‘tastes’ sweetness

Candy, cookies, juices. Just about everyone likes sweet treats, but what one person thinks tastes too sugary, another might think is just right. This variability makes it challenging to develop new foods and beverages, so companies have sought a more objective method. Now, researchers reporting in ACS Applied Materials & Interfaces have developed an ultrasensitive bioelectronic tongue that measures sweetness by mimicking human taste buds.

Although human sensory panels are the most common way to analyze a substance’s taste, there can be a lot of differences in how people perceive flavors. To get more objective data, researchers have made bioelectronic tongues in the lab, but they either are complicated to manufacture or can’t fully replicate the way the human tongue works. Human tongues have sweet taste receptors with two large, complex structures that bind to compounds such as sugars. The outermost portion of one of these structures is called the Venus flytrap domain because its hinged, two-lobed molecular structure resembles the leaves of the insectivorous plant that close around its prey. This domain interacts with most of the sweet substances a person consumes. In a previous study, Tai Hyun Park, Seunghun Hong and colleagues made an umami sensor with human-like performance by using just the protein at the end of the umami taste receptor. So, these researchers wanted to apply the same concept to make a sweet-sensing bioelectronic tongue, using the Venus flytrap domain as electronic taste buds.

The researchers attached copies of the Venus flytrap domain that were made by bacteria in a thin layer on a gold electrode. They then connected multiple gold electrodes together with carbon nanotubes, making a field-effect transistor device. When solutions of naturally sweet sucrose or of the artificial sweetener saccharin were applied to the device, the current decreased. The sensor responded to these solutions down to the 0.1 femtomolar level, which is 10 million times more sensitive than previous bioelectronic sweet sensors, the researchers say. The device could also consistently measure the sweetness of real drinks, such as apple juice and sucrose-sweetened chamomile tea, but it did not show a response when cellobiose (a tasteless sugar) or monosodium glutamate (a salt known as MSG) were introduced. Because the bioelectronic tongue was both sensitive and selective for sweet-tasting compounds, the researchers say this could be a powerful tool for the health care, pharmaceutical, and food and drink industries.

The authors acknowledge funding from the National Research Foundation (NRF) of Korea, the Ministry of Science and ICT (MSIT) of Korea, the Ministry of Trade, Industry and Energy (MOTIE) of Korea, Samsung Electronics, the European Research Council (ERC) within the European Union’s Horizon 2020 programme, and the Korea Institute of Science and Technology (KIST) Institutional Program.

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Materials provided by American Chemical Society. Note: Content may be edited for style and length.

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Two-thirds with Omicron say they have had Covid before

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Liquid water beneath Martian south polar cap?

A Southwest Research Institute scientist measured the properties of ice-brine mixtures as cold as -145 degrees Fahrenheit to help confirm that salty water likely exists between grains of ice or sediment under the ice cap at Mars’ south pole. Laboratory measurements conducted by SwRI geophysicist Dr. David Stillman support oddly bright reflections detected by the MARSIS subsurface sounding radar aboard ESA’s Mars Express orbiter.

With a 130-foot antenna, MARSIS flies over the planet, bouncing radio waves over a selected area and then receiving and analyzing the echoes or reflections. Any near-surface liquid water should send a strong bright signal, whereas the radar signal for ice and rock would be much smaller.

Because conventional models assume the Mars south polar cap experiences temperatures much lower than the melting point of water, many scientists have questioned the presence of liquid water. Clay, hydrated salts and saline ices have been proposed as potential explanations for the source of the bright basal reflections. The Italian-led team investigating the proposed phenomena used previously published data, simulations and new laboratory measurements.

“Lakes of liquid water actually exist beneath glaciers in Arctic and Antarctic regions, so we have Earth analogs for finding liquid water below ice,” said Stillman, a specialist in detecting water in any format — liquid, ice or absorbed — on planetary bodies and co-author of a paper describing these findings. “The exotic salts that we know exist on Mars have amazing ‘antifreeze’ properties allowing brines to remain liquid down to -103 degrees Fahrenheit. We studied these salts in our lab to understand how they would respond to radar.”

Stillman has over a decade of experience measuring the properties of materials at cold temperatures to detect and characterize subsurface ice, unfrozen water and the potential for life throughout the solar system. For this project, Stillman measured the properties of perchlorate brines in an SwRI environmental chamber that produces near-liquid-nitrogen temperatures at Mars-like pressures.

“My Italian colleagues reached out to see if my laboratory experiment data would support the presence of liquid water beneath the Martian ice cap,” Stillman said. “The research showed that we don’t have to have lakes of perchlorate and chloride brines, but that these brines could exist between the grains of ice or sediments and are enough to exhibit a strong dielectric response. This is similar to how seawater saturates grains of sand at the shoreline or how flavoring permeates a slushie, but at -103 degrees Fahrenheit below a mile of ice near the South Pole of Mars.”

The search for water in the cosmos is rooted in searching for potential habitability, because all known life requires water.

“In this case ‘following the water’ has led us to place so cold that life as we know it couldn’t flourish,” Stillman said. “But it’s still interesting, and who knows what evolutionary paths extraterrestrial life may have taken?”

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Materials provided by Southwest Research Institute. Note: Content may be edited for style and length.

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Pfizer and BioNTech start trials of new Omicron-specific jab

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