Health24.com | Should you be worried about your own health as a caregiver?

Being a family caregiver may not be as hazardous to your health as most people think, researchers say.

Decades of research papers and media reports have warned that family caregivers are at risk for health declines. One suggested reason is that the stress of caregiving can increase inflammation and weaken the immune system. Caregiving can of course be challenging when having to deal with aspects like incontinence.

Fear of caregiving

For this study, researchers at Johns Hopkins University in Baltimore reviewed 30 papers published between 1987 and 2016. They concluded that stress explains less than 1% of the variability in caregivers’ immune and inflammation biomarkers.

“We’re not saying that family caregiving can’t be stressful, but there’s a notion that it’s so stressful that it causes deteriorating health and increased mortality. This can lead to fear of caregiving and a reluctance to care for loved ones in need,” said first author David Roth, director of Hopkins’ Center on Aging and Health.

That narrative is “exaggerated”, he said.

“It’s not that we didn’t find anything, but it’s a whisper of an effect, not nearly as large as what people have been led to believe,” Roth said in a Hopkins news release.

Pro-social behaviour

He and his colleagues hope their findings will encourage people to be more open to caregiving, and convince health care providers to move away from the idea that caregivers are vulnerable.

“Caregiving, if done right, can actually be an extremely beneficial, healthy activity that enhances your life because you’re engaging in pro-social behaviour,” Roth said.

The study was recently published in The Gerontologist journal.

More than 34 million people in the United States provide care for a chronically ill, disabled or aged family member or friend, according to the National Alliance for Caregiving. The value of that care is estimated at $375bn a year.

Image credit: iStock

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Health24.com | Many teens don’t know they are vaping nicotine

As e-cigarette use soars in high schools across America, new research shows many people don’t understand the amount of addictive nicotine they’re inhaling with every puff.

In a new survey, many teens said they regularly used e-cigarettes, but swore they only vaped nicotine-free products.

However, urine tests for a “marker” of nicotine use came up positive 40% of the time in this same group of vapers, the researchers reported.

“Many of our participants were unaware of the nicotine content of the e-cigarette products they were using”, concluded a team led by Dr Rachel Boykan, a paediatrics researcher at Stony Brook University in Stony Brook, New York.

That could mean even more lifelong nicotine addictions arising in the young, including many who already believe vaping to be “harmless” compared to traditional smoking, experts said.

Patricia Folan directs the Center for Tobacco Control at Northwell Health in Great Neck, New York. She said, “Other studies have revealed that one of the main reasons adolescents use e-cigarettes is that they perceive them to be less harmful than combustible cigarettes – without full knowledge of their actual contents.”

But the new study “shows that many of the participating youth were unaware of the nicotine content in their vaping devices,” Folan said.

The study findings were published online in the journal Pediatrics.

Nicotine-laden vaping products

As Boykan’s group noted, about one in five high school students now say they’ve used an e-cigarette at least once over the past month, and in just the 12 months between 2017 and 2018, teen vaping rates soared 78%.

But do young people understand the addictive dangers of nicotine-laden vaping products such as Juul vape “pods”?

To find out, the Stony Brook team first had 517 people, aged 12 to 21, complete questionnaires about their use of e-cigarettes, traditional cigarettes and marijuana. The investigators then compared those survey results against the results of urine tests that looked for a chemical called cotinine.

Cotinine is a well-known “marker” for the presence of nicotine in a person’s body.

Overall, the survey participants were largely honest about their use of tobacco, e-cigarettes and marijuana: Only about 2% who said they didn’t use those substances later were found to have evidence of tobacco, nicotine or pot in their urine samples.

The big discrepancy came among young vapers, Boykan’s team found.

Risk for addiction clear

In this subgroup, about four of every ten people who said they only vaped non-nicotine products were found to have markers for nicotine in their urine.

In many cases, this lack of awareness occurred with use of Juul vaping pods, which actually “have the highest nicotine concentrations to date”, the researchers reported.

These products have also “become the most widely used [vaping] products among adolescents”, the study authors added.

“The risk for addiction is clear,” said Dr Len Horovitz, a lung health specialist who wasn’t involved in the new study. The fact that many young vapers may not even realise that they are ingesting nicotine is “disturbing”, he said.

“It’s well known that e-cigarettes end up delivering more nicotine because every ‘draw’ yields nicotine, whereas traditional cigarettes burn down between puffs and therefore deliver less nicotine,” Horovitz said. He works in pulmonary care at Lenox Hill Hospital in New York City.

For her part, Folan believes more must be done to alert kids to the danger.

“This study demonstrates the need for more regulation regarding e-cigarettes, including labelling of ingredients and health warnings,” she said. Better education about what’s in a vaping product “may help teens make more educated decisions”, Folan added.

Image credit: iStock

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Severe pregnancy sickness: ‘I thought I was dying’

Hannah is one of 5,000 UK women to share their experience of extreme pregnancy sickness with BBC News.

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Thyroid disease ‘being over-treated’

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Low-Dose Aspirin May Lead to Bleeding in the Skull, Study Says

For years, many patients have been advised to take low-dose aspirin daily to protect against cardiovascular problems like heart attack and stroke. But a growing body of research has also served as a reminder that aspirin is not a cure-all—and that it also comes with its own risks.

Now, a new review of previously published studies has issued one of the strongest cautions to-date about aspirin and its potential side effects. The review, published yesterday in JAMA Neurology, suggests that taking aspirin unnecessarily may lead to bleeding in the skull.

Before you panic, keep in mind that we’re not talking about people who grab the aspirin bottle every now and then when they have a headache. We’re looking at people who take aspirin daily, based on the advice of a friend or neighbor who told them that regularly popping these pills can prevent heart trouble.

The authors of the new research analyzed records of 13 previous studies including 134,446 patients, and came to this conclusion: “Among people without symptomatic cardiovascular disease, use of low-dose aspirin was associated with an overall increased risk of intracranial hemorrhage.” (Intracranial hemorrhage translates to bleeding in the skull.)

Specifically, heart-healthy people who regularly took low-dose aspirin were 37% more likely to experience brain bleeding, compared to those who took a placebo. The study may have especially important implications for people of Asian ethnicity and those with a BMI under 25 (considered underweight): People who fell into those categories had an especially heightened risk of these dangerous complications.

The study’s authors wrote that the effects of taking low-dose aspirin are “modest but clinically relevant.” Out of every 1,000 people treated with the medication and analyzed for the study, two more experienced bleeding in the skull—which, the authors point out, has been tied to a higher risk of death and disability.

Given the fact that many people have a “very low risk of atherosclerotic events,” the authors wrote, “adverse outcomes from intracranial hemorrhage may outweigh the beneficial effects of low-dose aspirin” if aspirin were be to prescribed to everyone regardless of their heart-health status.

Health spoke with an expert to find out how serious this new warning is. “The average person might read this, and it seems scary,” says Sarah Song, MD, a Chicago-based fellow of the American Academy of Neurology. “But remember that, as with anything you put in your body, there are pros and cons.”

People who have struggled with heart trouble can still benefit from a daily low-dose aspirin, says Dr. Song. “For people who have had a heart attack or stroke and they’re on aspirin, this [new warning] doesn’t apply to them,” she says. “It’s for the people taking aspirin just to take aspirin.”

The idea that aspirin can cause bleeding isn’t new or surprising, but the new review serves as a good reminder, Dr. Song adds. “You should know aspirin is not harmless,” she says.

RELATED: More Young Women Are Having Heart Attacks. This Might Be Why

If your doctor has prescribed you daily aspirin, don’t stop taking it because of this report, Dr. Song says. But if you’re taking aspirin based on the advice of someone else, you might want to talk to your doctor about whether or not it’s necessary for you.

Additionally, if you’ve started taking aspirin somewhat regularly because of chronic pain, you might want to consult your physician about this. “Taking aspirin regularly for pain management is not a long-term solution,” Dr. Song says. Taking ibuprofen might be a better solution, she adds, depending on the reason you need relief.

Dr. Song adds that more research is needed to learn why this problem disproportionately affects Asian populations. But the study authors point out that these findings are consistent with other research on this topic. Previous studies have suggested that Asian individuals may have a higher risk of intracerebral bleeding because of environmental or dietary factors, or because they have higher rates of smoking and high blood pressure.

RELATED: Luke Perry's Death Has People Wondering: What Causes a Massive Stroke at a Young Age, Anyway?

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Generating high-quality single photons for quantum computing

MIT researchers have designed a way to generate, at room temperature, more single photons for carrying quantum information. The design, they say, holds promise for the development of practical quantum computers.

Quantum emitters generate photons that can be detected one at a time. Consumer quantum computers and devices could potentially leverage certain properties of those photons as quantum bits (“qubits”) to execute computations. While classical computers process and store information in bits of either 0s or 1s, qubits can be 0 and 1 simultaneously. That means quantum computers could potentially solve problems that are intractable for classical computers.

A key challenge, however, is producing single photons with identical quantum properties — known as “indistinguishable” photons. To improve the indistinguishability, emitters funnel light through an optical cavity where the photons bounce back and forth, a process that helps match their properties to the cavity. Generally, the longer photons stay in the cavity, the more they match.

But there’s also a tradeoff. In large cavities, quantum emitters generate photons spontaneously, resulting in only a small fraction of photons staying in the cavity, making the process inefficient. Smaller cavities extract higher percentages of photons, but the photons are lower quality, or “distinguishable.”

In a paper published today in Physical Review Letters, the researchers split one cavity into two, each with a designated task. A smaller cavity handles the efficient extraction of photons, while an attached large cavity stores them a bit longer to boost indistinguishability.

Compared to a single cavity, the researchers’ coupled cavity generated photons with around 95 percent indistinguishability, compared to 80 percent indistinguishability, with around three times higher efficiency.

“In short, two is better than one,” says first author Hyeongrak “Chuck” Choi, a graduate student in the MIT Research Laboratory of Electronics (RLE). “What we found is that in this architecture, we can separate the roles of the two cavities: The first cavity merely focuses on collecting photons for high efficiency, while the second focuses on indistinguishability in a single channel. One cavity playing both roles can’t meet both metrics, but two cavities achieves both simultaneously.”

Joining Choi on the paper are: Dirk Englund, an associate professor of electrical engineering and computer science, a researcher in RLE, and head of the Quantum Photonics Laboratory; Di Zhu, a graduate student in RLE; and Yoseob Yoon, a graduate student in the Department of Chemistry.

The relatively new quantum emitters, known as “single-photon emitters,” are created by defects in otherwise pure materials, such as diamonds, doped carbon nanotubes, or quantum dots. Light produced from these “artificial atoms” is captured by a tiny optical cavity in photonic crystal — a nanostructure acting as a mirror. Some photons escape, but others bounce around the cavity, which forces the photons to have the same quantum properties — mainly, various frequency properties. When they’re measured to match, they exit the cavity through a waveguide.

But single-photon emitters also experience tons of environmental noise, such as lattice vibrations or electric charge fluctuation, that produce different wavelength or phase. Photons with different properties cannot be “interfered,” such that their waves overlap, resulting in interference patterns. That interference pattern is basically what a quantum computer observes and measures to do computational tasks.

Photon indistinguishability is a measure of photons’ potential to interfere. In that way, it’s a valuable metric to simulate their usage for practical quantum computing. “Even before photon interference, with indistinguishability, we can specify the ability for the photons to interfere,” Choi says. “If we know that ability, we can calculate what’s going to happen if they are using it for quantum technologies, such as quantum computers, communications, or repeaters.”

In the researchers’ system, a small cavity sits attached to an emitter, which in their studies was an optical defect in a diamond, called a “silicon-vacancy center” — a silicon atom replacing two carbon atoms in a diamond lattice. Light produced by the defect is collected into the first cavity. Because of its light-focusing structure, photons are extracted with very high rates. Then, the nanocavity channels the photons into a second, larger cavity. There, the photons bounce back and forth for a certain period of time. When they reach a high indistinguishability, the photons exit through a partial mirror formed by holes connecting the cavity to a waveguide.

Importantly, Choi says, neither cavity has to meet rigorous design requirements for efficiency or indistinguishability as traditional cavities, called the “quality factor (Q-factor).” The higher the Q-factor, the lower the energy loss in optical cavities. But cavities with high Q-factors are technologically challenging to make.

In the study, the researchers’ coupled cavity produced higher quality photons than any possible single-cavity system. Even when its Q factor was roughly one-hundredth the quality of the single-cavity system, they could achieve the same indistinguishability with three times higher efficiency.

The cavities can be tuned to optimize for efficiency versus indistinguishability — and to consider any constraints on the Q factor — depending on the application. That’s important, Choi adds, because today’s emitters that operate at room temperature can vary greatly in quality and properties.

Next, the researchers are testing the ultimate theoretical limit of multiple cavities. One more cavity would still handle the initial extraction efficiently, but then would be linked to multiple cavities that photons for various sizes to achieve some optimal indistinguishability. But there will most likely be a limit, Choi says: “With two cavities, there is just one connection, so it can be efficient. But if there are multiple cavities, the multiple connections could make it inefficient. We’re now studying the fundamental limit for cavities for use in quantum computing.”

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