Cancel Thanksgiving

The USA just reached 10 million reported COVID infections earlier this month. Now it’s beyond 12.5 million and is on track to hit 14 million by the end of the month. It’s been estimated that at least 3 million people are probably infectious right now, and many don’t know it because they’re asymptomatic. The real number could be a lot higher.

A few days ago we hit another new high: 204K new cases in one day. This is after just recently breaking 100K for the first time.

Deaths are still ticking up as well, now around 2K per day. I imagine that’s going to be a lot higher in December.

In some U.S. states, the infection rate is so high that even with a modest-sized family gathering, it’s likely that at least one attendee is infected.

Some places that were previously doing contact tracing have abandoned the practice because they can’t keep up with all of the cases.

In my state of Nevada, the Governor just tightened up some restrictions because the infection rate is surging here too. A couple of months ago, we were seeing 250-500 new cases per day. Now it’s around 2000 per day with a recent high of 2416. And the infection rate here is modest compared to what some places are currently seeing. Even so, a major hospital still had to convert a parking garage into overflow space for COVID patients, and it’s already being actively used.

This Thanksgiving will be the last one for many people who aren’t intelligent, informed, or caring enough to cancel family gatherings this year. Millions of people are heading for an avoidable trap.

If you intend to host or attend a family Thanksgiving event this year, think again and cancel those plans. It isn’t safe. Such behavior is incredibly reckless right now.

If you have some intractable and clueless relatives, would you rather see them terribly disappointed, terribly sick, or peacefully dead (after being unable to breathe for a while)?

A few weeks from now, a lot of people will be crying and wishing they’d made a different decision. Don’t be one of them.

Sometimes the right decision isn’t to seize an opportunity but to avoid a calamitous mistake. Remember that you’ll have the memory of what you do this Thanksgiving for the rest of you life. No matter what you decide, you’ll carry that memory into 2030, 2040, and beyond. Which memory do you want?

You only control one side of this decision. You don’t get to control reality’s responses. And reality is clearly queuing up a big lesson for a lot of people, namely that it doesn’t respect fools.

If this is all just common sense to you – and it absolutely should be – please also do your part to actively and vehemently discourage your friends and family from having family gatherings during this time.

I know from years of experience that while my readers tend to be very smart and sensible, many have relatives who are… how shall I put this… dumb as a stump. If that’s your situation, then here’s your chance to put your personal development investments into practice. Let’s see that fancy courage you’ve been working on all these years. Get aligned and stay aligned with truth. Don’t be loyal to ignorance and denial, even if you share some blood with it.

I can assure you that no one will die from our Thanksgiving, and no animals will be harmed either. Rachelle and I are staying put, and no one is coming over.

Use your brain and don’t be stupid this year.

There will be another time. Not this year.

If you need to use it as such, this article also doubles as a permission slip to skip Thanksgiving this year.

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Health24.com | Another Covid vaccine candidate reports promising results – what we know

  • Results from the Oxford University Covid-19 vaccine trial shows promising results, with up to 90% efficacy reported
  • The vaccine will now await regulatory approval from independent regulator, the MHRA 
  • The UK government has pre-ordered 100 million doses, and AstraZeneca stated that it will seek an Emergency Use Listing from WHO for vaccine availability in low-income countries

Positive data from an interim analysis of the University of Oxford’s Covid-19 vaccine trial in the UK and Brazil shows that it protects 70% of people from developing Covid symptoms, Oxford’s manufacturing partner, AstraZeneca announced on Monday.

The data is from the COV002 Phase 2/3 trial in the UK and COV003 Phase 3 trial in Brazil, which involves more than 23 000 participants. No hospitalisations or severe cases of the disease were reported in volunteers who received the vaccine, named AZD1222.

A total of 30 cases of Covid-19 were found in participants who received two jabs of the vaccine, and 101 cases in people who received a saline injection. According to the researchers, it translates to 70% protection.

Additional data from the large-scale trial also suggests that perfecting the dose could increase protection up to 90%. This was seen for one course of dosing, where volunteers received a half dose of the vaccine, followed by a full dose at least one month after.

When participants were given two “high” doses, it resulted in 62% protection. However, this increased to 90% when participants received a “low” dose followed by a high one. 

Chief investigator pleased with results

Professor Andrew Pollard, the trial’s lead investigator said: “Excitingly, we’ve found that one of our dosing regimens may be around 90% effective and if this dosing regime is used, more people could be vaccinated with planned vaccine supply.”

The researchers stated that it’s not clear why there is a difference, although Pollard told the BBC that the team is “really pleased with these results”.

There were also lower levels of asymptomatic infection in the low followed by high dose group which “means we might be able to halt the virus in its tracks,” Pollard said.

Vaccine’s architect Professor Sarah Gilbert also commented: “The announcement today takes us another step closer to the time when we can use vaccines to bring an end to the devastation caused by [the virus].”

The vaccine uses an adenovirus, which causes the common cold in chimpanzees, that has been genetically engineered so that it’s unable to replicate and cause disease in humans. 

How does the Oxford vaccine fare, compared to Pfizer and Moderna’s vaccines?

This news follows shortly after the positive results announced by Pfizer/BioNTech and Moderna, whose vaccines showed 95% and 94.5% protection respectively. Both companies have applied to regulatory authorities for approval.

While 70% may seem like a disappointing result in comparison to these two vaccines, the Food and Drug Administration (FDA) requires a Covid-19 vaccine to prevent disease in 50% of volunteers in order to gain approval.

Logistics less complex

Logistics of storing and transporting the Oxford vaccine will be far less complex than the Pfizer and Moderna vaccines, as it can be stored at fridge temperature, making it more favourable to distribute worldwide.

The Pfizer/BioNTech vaccine needs to be stored below freezing temperatures (minus 70 degrees Celsius), while Moderna’s vaccine needs to be shipped and transported at minus 20 degrees Celsius.

Reporting by Bhekisisa earlier this month notes that despite its promise, cold chain requirements mean these jabs wouldn’t be the first choice for countries like South Africa.

In addition to the above, the Oxford vaccine is also much cheaper than the Pfizer and Moderna vaccines.

This means that it will play a significant role in fighting the spread of the virus, if it is approved by regulators, which is due to take place in the next couple of weeks.

“I’m really very pleased, I really welcome these figures – this data – that show that the vaccine in the right dosage can be up to 90% effective,” Health Secretary Matt Hancock told Sky News.

“Of course, it’s vital that the independent regulator – the MHRA (Medicines and Healthcare products Regulatory Agency) – will need to look at the data, will need to check to make sure that it’s effective and safe.” 

Comments on results by lead investigator of SA’s trial

Clinical trials are also being carried out in the US, Japan, Russia, South Africa, Kenya and Latin America. Planned trials are due to take place in other European and Asian countries. A total of 60 000 participants are expected to be enrolled globally.

This vaccine candidate was also the first of Covid-19 vaccines to be trialled in South Africa. Named the Ox1Cov-19 Vaccine VIDA trial, it is done in collaboration with Oxford University. The SA trial is being led by Shabir Madhi, Professor in Vaccinology at Wits University.

Commenting on the results, Madhi said in a press release by the university:

“The results from this study add further hope that accessing vaccines to fight the Covid-19 pandemic are fast becoming a reality.

“The results from this study are intriguing, in that a dose-sparing regimen may inadvertently end up being more protective. This has implications not only for the cost of the vaccine, but also how many more people could possibly be vaccinated in the near future when vaccine supply is likely to be constrained.

“Also, the ability to scale up production of this vaccine, and it only needing to be stored at 2-8 degrees Celcius, would greatly assist in the deployment of the vaccine in low- and middle-income countries. The cost of this vaccine is also anticipated to be much cheaper than other Covid-19 vaccines that have recently been shown to be efficacious.”

Madhi emphasised the importance of testing the vaccine in diverse populations, such as South Africa:

“The results of the study from South Africa remain of global interest, and to inform recommendations on Covid-19 vaccine in Africa, as the Covid-19 experience in South Africa has been very different to the UK.

“As for many other vaccines, genetic factors and local conditions could also affect the performance of the vaccine in different populations. The results of the pooled analysis from UK and Brazil creates optimism that we will also show protection against Covid-19 in the South African study, where participants are still being followed-up.”

Who’s first in line to receive the vaccine?

According to the BBC, AstraZeneca is preparing to produce three billion doses for the world next year.

The UK government has already pre-ordered 100 million doses, enough to immunise 50 million people. If approved, four million is expected to roll out by the end of the year.

Earlier this year, Madhi explained that AstraZeneca, however, doesn’t have any direct involvement with SA’s vaccine trial as the agreement to do the trial here preceded Oxford’s agreement with AstraZeneca for further clinical development and manufacturing of the vaccine.

But spokesman for the Department of Health, Popo Maja, confirmed to Spotlight this month that although SA had not concluded any vaccine deal, negotiations with manufacturers and COVAX (an initiative co-lead by the World Health Organization that aims to ensure developing countries get access to Covid-19 vaccines) are underway.

AstraZeneca’s press release notes that “it will now immediately prepare regulatory submission of the data to authorities around the world that have a framework in place for conditional or early approval.

“The Company will seek an Emergency Use Listing from the World Health Organization for an accelerated pathway to vaccine availability in low-income countries. In parallel, the full analysis of the interim results is being submitted for publication in a peer-reviewed journal,” they stated.

READ | Covid-19: Two of the vaccine front runners have already reported promising evidence – so what now?

READ | Cold truth: South Africa won’t be able to store these Covid vaccines. Here’s why.

READ | The latest news on a leading Covid vaccine candidate is promising, but how optimistic should we be?

Image: Getty/zhangshuang

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News24.com | Why rapid isolation is needed for confirmed Covid-19 virus cases

  • A large, comprehensive meta-analysis revealed key findings about the new coronavirus
  • For the study, the authors looked at SARS-CoV-2, SARS-CoV, and MERS-CoV
  • Their findings indicate that SARS-CoV-2 is more infectious than the other two coronaviruses

People infected with SARS-CoV-2, the virus that causes Covid-19, are most likely to be highly infectious in the first week after displaying symptoms, according to a new systematic review and meta-analysis of three human coronaviruses: SARS-CoV-2, SARS-CoV, and MERS-CoV.

The results, published in Lancet Microbe, highlight the need for early identification and isolation of cases. 

The study

To understand when individuals are most likely to be infectious is of critical importance for informing effective public health measures to control the spread of the pandemic, the authors wrote.

They, therefore, looked at the following factors:

  • Viral load (how the amount of virus in the body changes throughout infection) 
  • Viral RNA shedding (the length of time someone sheds viral genetic material)
  • Isolation of the live virus (a stronger indicator of a person’s infectiousness)

Viral RNA does not necessarily indicate that a person is infectious, as this is not necessarily able to replicate, the scientists explained, while isolation of the live virus means that the virus is tested to see if it can be successfully replicated in the laboratory.

A total of 98 studies that included five or more participants, cohort studies and randomised controlled trials were included in the analysis. Seventy-nine focused on SARS-CoV-2 (73 of which included hospitalised patients only); eight on SARS-CoV; and 11 on MERS-CoV infection. 

The team calculated the average length of viral RNA shedding and studied the changes in viral load, as well as the success of isolating the live virus from different samples collected throughout an infection.

Possible explanation for quick spread

The researchers’ findings indicate that SARS-CoV-2 viral load appears to peak in the upper respiratory tract (thought to be the main source of transmission) early in the course of the disease, which occurs from symptom onset to day five.

On the other hand, they report that SARS-CoV (which first appeared in 2002) and MERS-CoV (Middle East respiratory syndrome, which first appeared in 2012) viral loads peak later. This may explain why the Covid-19 outbreak occurred more rapidly in communities.

“This is the first systematic review and meta-analysis that has comprehensively examined and compared viral load and shedding for these three human coronaviruses. It provides a clear explanation for why SARS-CoV-2 spreads more efficiently than SARS-CoV and MERS-CoV and is so much more difficult to contain,” said lead author Dr Muge Cevik of the University of St Andrews, UK.

“Our findings are in line with contact tracing studies which suggest the majority of viral transmission events occur very early, and especially within the first five days after symptom onset, indicating the importance of self-isolation immediately after symptoms start.”

Cevik further explained that public awareness about the range of symptoms linked with the disease, “including mild symptoms that may occur earlier on in the course of the infection than those that are more prominent like cough or fever”. 

Virus detected in stools weeks later, but not infectious

Another important component of the virus that scientists have been studying for many months is whether SARS-CoV-2 genetic material detected in stool samples several weeks later can cause infection.

According to the authors of this study, no live virus (that can cause infection) was found in any type of sample collected beyond nine days of symptom onset. They, therefore, suggest that, based on their evidence, people infected with the new coronavirus are mostly likely to be highly infectious from symptom onset and the following five days.

Asymptomatic cases: ‘silent drivers’?

The study authors also note that while viral loads appear to be similar in people infected with the virus who develop symptoms and those who do not (asymptomatic), most studies indicate that asymptomatic individuals may clear the virus faster from their body and might be infectious for a shorter length of time.

An article in Nature, for example, points to evidence that suggests that about one in five infected people is asymptomatic, and they will transmit the virus to significantly fewer people than someone with symptoms, although researchers are still divided about their contribution to the Covid-19 outbreak.

Second PCR test not always needed

The findings also suggest that in clinical practice, a repeat PCR test may result in a positive result, but it would not necessarily indicate that a patient could pass on the virus to others.

“Repeat PCR testing may not be needed to deem that a patient is no longer infectious,” said Cevik. 

Study limitations

This study focused on individuals infected with SARS-CoV-2 and mainly those who were hospitalised. As a result, they received a range of treatments that may affect the course of their infection, the authors wrote.

“The majority of studies included in our review were performed in patients who were admitted to hospital. Therefore, our findings may not apply to people with milder infection although these results suggest those with milder cases may clear the virus faster from their body.

“Additionally, the increasing deployment of treatments, such as dexamethasone, remdesivir, as well as other antivirals and immunomodulators in clinical trials are likely to influence viral shedding in hospitalised patients. Further studies on viral shedding in this context are needed,” said senior author, Dr Antonia Ho of MRC-University of Glasgow Centre for Virus Research, UK. 

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Covid risk: 3 people, 3 very different Covid risks. What’s yours?

A question everyone’s asking: what’s my Covid risk? Here’s how to find out.

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U.S. should look at how other high-income countries regulate health care costs, experts urge

Structuring negotiations between insurers and providers, standardizing fee-for-service payments and negotiating prices can lower the United States’ health care spending by slowing the rate at which healthcare prices increase, according to a Rutgers study.

The study, published in the journal Health Affairs, examined how other high-income countries that use a fee-for-service model regulate health care costs.

Although the United States has the highest health care prices in the world, the specific mechanisms commonly used by other countries to set and update prices are often overlooked. In most countries with universal health insurance, physicians are paid on a fee-for-service basis, yet health care prices there are lower than in the U.S. To lower health care spending, American policymakers have focused on eliminating fee-for-service reimbursement, which provides an incentive for performing additional services rather than setting up price negotiations to address the main factor that drives health care spending.

U.S. policy makers emphasize the need to reduce the volume of care that the system provides, but prior research shows that U.S. health care expenditures are higher than in other countries because of the price, not the volume, of services.

The researchers compared policies in France, Germany and Japan where payers and physicians engage in structured fee negotiations and standardized prices in systems where fee-for-service is the main model of outpatient physician reimbursement. They interviewed 37 stakeholders and health policy experts in those three countries to understand the process for creating physician fee schedules and updates, to learn about recent policy changes in physician payment and to identify the remaining challenges in the use of fee-for-service payment to physicians.

“The parties involved, the frequency of fee schedule updates and the scope of the negotiations vary, but all three countries attempt to balance the interests of payers with those of physician associations,” said lead author Michael K. Gusmano, lead study author and a professor at the Rutgers School of Public Health and research scholar at The Hastings Center.

Expanding public insurance and creating universal health care coverage for U.S. residents have been popular — even more so during the COVID-19 pandemic. However, addressing the price of health care is crucial for making universal coverage affordable.

The use of fee-for-service physician payment does create issues, but marking fee-for-service as the major cause of high health care spending in the United States is problematic, especially as countries with lower prices and expenditures use fee-for-service systems, while also providing universal health care to its residents. France, Germany and Japan limit the incomes of physicians by standardizing and adjusting the fees they are paid while using a variety of approaches to limit the volume of services provided.

According to Gusmano — who is also a member of the Rutgers Institute for Health, Health Care Policy and Aging Research and Rutgers Global Health Institute — regardless of whether the United States will pursue fundamental policy changes such as Medicare for All or incremental expansion of the Affordable Care Act, both would require that policy makers address health care prices.

Story Source:

Materials provided by Rutgers University. Original written by Michelle Edelstein. Note: Content may be edited for style and length.

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Breaking the ice on melting and freezing

Eric Hester has spent the last three years chasing icebergs. A mathematics graduate student at the University of Sydney in Australia, Hester and researchers at Woods Hole Oceanographic Institution in Massachusetts are studying how the shape of an iceberg shapes the way it melts.

“Ice deforms as it melts,” said physical oceanographer Claudia Cenedese, who has worked with Hester on the project. “It makes these very weird shapes, especially on the bottom, like the way the wind shapes a mountain on a longer time scale.”

At the 73rd Annual Meeting of the American Physical Society’s Division of Fluid Dynamics, Hester presented results from his group’s experiments aimed at understanding how melting alters the face-changing boundary of a shrinking iceberg — and how those alterations in turn affect the melting.

The dynamics of iceberg melt is missing from most climate models, Cendese said. Including them could help with prediction: icebergs pump fresh water from ice sheets into oceans, boosting communities of living organisms. Icebergs are the dominant source of freshwater in the fjords of Greenland — and a significant contributor to freshwater loss in Antarctica. Icebergs play a critical role in the climate, Cenedese said, and shouldn’t be neglected in models. The physics of melting ice is well understood, and some models simulate it accurately, she said. Others don’t. “But what you can’t do in those simulations is change the shape of the ice.”

Icebergs form with a wide range of shapes and sizes, Hester said, and distinct thermodynamic processes affect different surfaces. The base, submerged in water, doesn’t melt in the same way as the side. “And each face doesn’t melt uniformly,” added Cenedese.

Hester conducted his experiments by submerging a dyed block of ice in a flume with a controlled flow of water passing by, and watching it melt. He and his colleagues found that the side facing a current melts faster than sides that run parallel to flow. By combining experimental and numerical approaches, Hester and his collaborators charted the relative influences of factors like relative water velocity and aspect ratio, or the proportion of height to width on a side. Not surprisingly, they found that the bottom had the slowest melt rate.

Cenedese said Hester’s project brings together collaborators from a range of disciplines and countries, and that a diverse collaboration was needed for such an interdisciplinary project. “Working in isolation isn’t as productive in this case.”

Other studies discussed at the conference focused on ice formation, rather than melting. During a session on particle-laden flows, engineer Jiarong Hong from the St. Anthony Falls Laboratory at the University of Minnesota, in Minneapolis, discussed results from experiments showing how turbulence influences both the speed and distribution of snow as it falls and settles. The findings could also help scientists better understand precipitation, Hong said.

Another project, presented by physicist Chao Sun from Tsinghua University in China and his group during a session on convection and buoyancy-driven flows, focused on ice formation in lakes.

Working on a grant from the Natural Science Foundation of China with Ziqi Wang from Tsinghua University, Enrico Calzavarini from the University of Lille in France, and Federico Toschi from Eindhoven University of Technology in the Netherlands, Sun showed how the formation of ice on a lake is closely tied to the fluid dynamics of the water beneath.

A lake may possess layers of water of differing densities and temperatures. “The water density anomalies can induce elaborate fluid dynamics beneath a moving ice front and can drastically change system behaviors,” said Sun. “This has often been ignored in previous studies.”

Sun’s group combined physical experiments, numerical simulations, and theoretical models to investigate the connection between the ice and (turbulent) convective flows. They identified four distinct regimes of different flow dynamics, each of which interacts with other layers and the ice in its own ways. Even with that complexity, though, the group developed an accurate theoretical model that could be used in future studies.

“It made a fair prediction of ice layer thickness and of icing time,” said Sun.

Since the formation and melting of ice plays such a critical role in the climate, he said, a better understanding of the fluid dynamics behind the process could help researchers identify and study accurately the markers of a warming world. “The time for ice to form and melt, for example, could potentially provide an indicator of climate change.”

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U.S.-European mission launches to monitor the world’s oceans

A joint U.S.-European satellite built to monitor global sea levels lifted off on a SpaceX Falcon 9 rocket from Space Launch Complex 4E at Vandenberg Air Force Base in California Saturday, Nov. 21, at 9:17 a.m. PST (12:17 p.m. EST).

About the size of a small pickup truck, Sentinel-6 Michael Freilich will extend a nearly 30-year continuous dataset on sea level collected by an ongoing collaboration of U.S. and European satellites while enhancing weather forecasts and providing detailed information on large-scale ocean currents to support ship navigation near coastlines.

“The Earth is changing, and this satellite will help deepen our understanding of how,” said Karen St. Germain, director of NASA’s Earth Science Division. “The changing Earth processes are affecting sea level globally, but the impact on local communities varies widely. International collaboration is critical to both understanding these changes and informing coastal communities around the world.”

After arriving in orbit, the spacecraft separated from the rocket’s second stage and unfolded its twin sets of solar arrays. Ground controllers successfully acquired the satellite’s signal, and initial telemetry reports showed the spacecraft in good health. Sentinel-6 Michael Freilich will now undergo a series of exhaustive checks and calibrations before it starts collecting science data in a few months’ time.

Continuing the Legacy

The spacecraft is named in honor of Michael Freilich, the former director of NASA’s Earth Science Division, who was a leading figure in advancing ocean observations from space. Freilich passed away Aug. 5, 2020. His close family and friends attended the launch of the satellite that now carries his name.

“Michael was a tireless force in Earth sciences. Climate change and sea level rise know no national borders, and he championed international collaboration to confront the challenge,” said ESA (European Space Agency) Director of Earth Observation Programmes Josef Aschbacher. “It’s fitting that a satellite in his name will continue the ‘gold standard’ of sea level measurements for the next half-decade. This European-U.S. cooperation is exemplary and will pave the way for more cooperation opportunities in Earth observation.”

“Mike helped ensure NASA was a steadfast partner with scientists and space agencies worldwide, and his love of oceanography and Earth science helped us improve understanding of our beautiful planet,” added Thomas Zurbuchen, NASA associate administrator for science at the agency’s headquarters. “This satellite so graciously named for him by our European partners will carry out the critical work Mike so believed in — adding to a legacy of crucial data about our oceans and paying it forward for the benefit of future generations.”

A joint U.S.-European satellite built to monitor global sea levels lifted off on a SpaceX Falcon 9 rocket from Space Launch Complex 4E at Vandenberg Air Force Base in California Saturday at 9:17 a.m. PST (12:17 p.m. EST).

About the size of a small pickup truck, Sentinel-6 Michael Freilich will extend a nearly 30-year continuous dataset on sea level collected by an ongoing collaboration of U.S. and European satellites while enhancing weather forecasts and providing detailed information on large-scale ocean currents to support ship navigation near coastlines.

The ocean-observing Sentinel-6 Michael Freilich satellite launched from Vandenberg Air Force Base in California aboard a SpaceX Falcon 9 rocket on Nov. 21, 2020 at 12:17 p.m. EST (9:17 a.m. PST, 5:17 p.m. UTC). Credit: NASA-JPL/Caltech

“The Earth is changing, and this satellite will help deepen our understanding of how,” said Karen St. Germain, director of NASA’s Earth Science Division. “The changing Earth processes are affecting sea level globally, but the impact on local communities varies widely. International collaboration is critical to both understanding these changes and informing coastal communities around the world.”

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After arriving in orbit, the spacecraft separated from the rocket’s second stage and unfolded its twin sets of solar arrays. Ground controllers successfully acquired the satellite’s signal, and initial telemetry reports showed the spacecraft in good health. Sentinel-6 Michael Freilich will now undergo a series of exhaustive checks and calibrations before it starts collecting science data in a few months’ time.

Continuing the Legacy

The spacecraft is named in honor of Michael Freilich, the former director of NASA’s Earth Science Division, who was a leading figure in advancing ocean observations from space. Freilich passed away Aug. 5, 2020. His close family and friends attended the launch of the satellite that now carries his name.

“Michael was a tireless force in Earth sciences. Climate change and sea level rise know no national borders, and he championed international collaboration to confront the challenge,” said ESA (European Space Agency) Director of Earth Observation Programmes Josef Aschbacher. “It’s fitting that a satellite in his name will continue the ‘gold standard’ of sea level measurements for the next half-decade. This European-U.S. cooperation is exemplary and will pave the way for more cooperation opportunities in Earth observation.”

“Mike helped ensure NASA was a steadfast partner with scientists and space agencies worldwide, and his love of oceanography and Earth science helped us improve understanding of our beautiful planet,” added Thomas Zurbuchen, NASA associate administrator for science at the agency’s headquarters. “This satellite so graciously named for him by our European partners will carry out the critical work Mike so believed in — adding to a legacy of crucial data about our oceans and paying it forward for the benefit of future generations.”

Sentinel-6 Michael Freilich will continue the sea level record that began in 1992 with the TOPEX/Poseidon satellite and continued with Jason-1 (2001), OSTM/Jason-2 (2008), and eventually Jason-3, which has been observing the oceans since 2016. Together, these satellites have provided a nearly 30-year record ofprecise measurements of sea level height while tracking the rate at which our oceans are rising in response to our warming climate. Sentinel-6 Michael Freilich will pass the baton to its twin, Sentinel-6B, in 2025, extending the current climate record at least another 10 years between the two satellites.

Global Science Impact

This latest mission marks the first international involvement in Copernicus, the European Union’s Earth Observation Programme. Along with measuring sea levels for almost the entire globe, Sentinel-6 Michael Freilich’s suite of scientific instruments will also make atmospheric measurements that can be used to complement climate models and help meteorologists make better weather forecasts.

“NASA is but one of several partners involved in Sentinel-6 Michael Freilich, but this satellite speaks to the very core of our mission,” said NASA Administrator Jim Bridenstine. “Whether 800 miles above Earth with this remarkable spacecraft or traveling to Mars to look for signs of life, whether providing farmers with agricultural data or aiding first responders with our Disasters program, we are tirelessly committed not just to learning and exploring, but to having an impact where it’s needed.”

The initial orbit of Sentinel-6 Michael Freilich is about 12.5 miles (20.1 kilometers) lower than its ultimate operational orbit of 830 miles (1,336 kilometers). In less than a month, the satellite will receive commands to raise its orbit, trailing Jason-3 by about 30 seconds. Mission scientists and engineers will then spend about a year cross-calibrating data collected by the two satellites to ensure the continuity of sea level measurements from one satellite to the next. Sentinel-6 Michael Freilich will then take over as the primary sea level satellite and Jason-3 will provide a supporting role until the end of its mission.

“This mission is the very essence of partnership, precision, and incredible long-term focus,” said Michael Watkins, director of NASA’s Jet Propulsion Laboratory in Southern California, which manages the mission. “Sentinel-6 Michael Freilich not only provides a critical measurement,it is essential for continuing this historic multi-decadal sea level record.”

Sentinel-6 Michael Freilich and Sentinel-6B compose the Sentinel-6/Jason-CS (Continuity of Service) mission developed in partnership with ESA. ESA is developing the new Sentinel family of missions to support the operational needs of the Copernicus program, managed by the European Commission. Other partners include the European Organisation for the Exploitation of Meteorological Satellites (EUMETSAT), and National Oceanic and Atmospheric Administration, with funding support from the European Commission and technical support from France’s National Centre for Space Studies.

“The data from this satellite, which is so critical for climate monitoring and weather forecasting, will be of unprecedented accuracy,” said EUMETSAT Director-General Alain Ratier. “These data, which can only be obtained by measurements from space, will bring a wide range of benefits to people around the globe, from safer ocean travel to more precise prediction of hurricane paths, from greater understanding of sea level rise to more accurate seasonal weather forecasts, and so much more.”

JPL, a division of Caltech in Pasadena, California, is contributing three science instruments to each Sentinel-6 satellite: the Advanced Microwave Radiometer for Climate, the Global Navigation Satellite System — Radio Occultation, and the Laser Retroreflector Array. NASA is also contributing launch services, ground systems supporting operation of the NASA science instruments, the science data processors for two of these instruments, and support for the U.S. component of the international Ocean Surface Topography Science Team. The launch is managed by NASA’s Launch Services Program, based at the agency’s Kennedy Space Center in Florida.

Read the Sentinel-6 Michael Freilich press kit:

To learn more about Sentinel-6 Michael Freilich, visit:

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Coronavirus: £3bn for NHS but Sunak warns of ‘economic shock’ to come

Borrowing – which hit a record £22.3bn in October – cannot go on indefinitely, chancellor says.

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Science reveals secrets of a mummy’s portrait

How much information can you get from a speck of purple pigment, no bigger than the diameter of a hair, plucked from an Egyptian portrait that’s nearly 2,000 years old? Plenty, according to a new study. Analysis of that speck can teach us about how the pigment was made, what it’s made of — and maybe even a little about the people who made it. The study is published in the International Journal of Ceramic Engineering and Science.

“We’re very interested in understanding the meaning and origin of the portraits, and finding ways to connect them and come up with a cultural understanding of why they were even painted in the first place,” says materials scientist Darryl Butt, co-author of the study and dean of the College of Mines and Earth Sciences.

Faiyum mummies

The portrait that contained the purple pigment came from an Egyptian mummy, but it doesn’t look the same as what you might initially think of as a mummy — not like the golden sarcophagus of Tutankhamen, nor like the sideways-facing paintings on murals and papyri. Not like Boris Karloff, either.

The portrait, called “Portrait of a Bearded Man,” comes from the second century when Egypt was a Roman province, hence the portraits are more lifelike and less hieroglyphic-like than Egyptian art of previous eras. Most of these portraits come from a region called Faiyum, and around 1,100 are known to exist. They’re painted on wood and were wrapped into the linens that held the mummified body. The portraits were meant to express the likeness of the person, but also their status — either actual or aspirational.

That idea of status is actually very important in this case because the man in the portrait we’re focusing on is wearing purple marks called clavi on his toga. “Since the purple pigment occurred in the clavi — the purple mark on the toga that in Ancient Rome indicated senatorial or equestrian rank- it was thought that perhaps we were seeing an augmentation of the sitter’s importance in the afterlife,” says Glenn Gates of the Walters Art Museum in Baltimore, where the portrait resides.

The color purple, Butt says, is viewed as a symbol of death in some cultures and a symbol of life in others. It was associated with royalty in ancient times, and still is today. Paraphrasing the author Victoria Finlay, Butt says that purple, located at the end of the visible color spectrum, can suggest the end of the known and the beginning of the unknown.

“So the presence of purple on this particular portrait made us wonder what it was made of and what it meant,” Butt says. “The color purple stimulates many questions.”

Lake pigments

Through a microscope, Gates saw that the pigment looked like crushed gems, containing particles ten to a hundred times larger than typical paint particles. To answer the question of how it was made, Gates sent a particle of the pigment to Butt and his team for analysis. The particle was only 50 microns in diameter, about the same as a human hair, which made keeping track of it challenging.

“The particle was shipped to me from Baltimore, sandwiched between two glass slides,” Butt says, “and because it had moved approximately a millimeter during transit, it took us two days to find it.” In order to move the particle to a specimen holder, the team used an eyelash with a tiny quantity of adhesive at its tip to make the transfer. “The process of analyzing something like this is a bit like doing surgery on a flea.”

With that particle, as small as it was, the researchers could machine even smaller samples using a focused ion beam and analyze those samples for their elemental composition.

What did they find? To put the results in context, you’ll need to know how dyes and pigments are made.

Pigments and dyes are not the same things. Dyes are the pure coloring agents, and pigments are the combination of dyes, minerals, binders and other components that make up what we might recognize as paint.

Initially, purple dyes came from a gland of a genus of sea snails called Murex. Butt and his colleagues hypothesize that the purple used in this mummy painting is something else — a synthetic purple.

The researchers also hypothesize that the synthetic purple could have originally been discovered by accident when red dye and blue indigo dye mixed together. The final color may also be due to the introduction of chromium into the mix.

From there, the mineralogy of the pigment sample suggests that the dye was mixed with clay or a silica material to form a pigment. According to Butt, an accomplished painter himself, pigments made in this way are called lake pigments (derived from the same root word as lacquer). Further, the pigment was mixed with a beeswax binder before finally being painted on linden wood.

The pigment showed evidence suggesting a crystal structure in the pigment. “Lake pigments were thought to be without crystallinity prior to this work,” Gates says. “We now know crystalline domains exist in lake pigments, and these can function to ‘trap’ evidence of the environment during pigment creation.”

Bottom of the barrel, er, vat

One other detail added a bit more depth to the story of how this portrait was made. The researchers found significant amounts of lead in the pigment as well and connected that finding with observations from a late 1800s British explorer who reported that the vats of dye in Egyptian dyers’ workshops were made of lead.

“Over time, a story or hypothesis emerged,” Butt says, “suggesting that the Egyptian dyers produced red dye in these lead vats.” And when they were done dyeing at the end of the day, he says, there may have been a sludge that developed inside the vat that was a purplish color. “Or, they were very smart and they may have found a way to take their red dye, shift the color toward purple by adding a salt with transition metals and a mordant [a substance that fixes a dye] to intentionally synthesize a purple pigment. We don’t know.”

Broader impacts

This isn’t Butt’s first time using scientific methods to learn about ancient artwork. He’s been involved with previous similar investigations and has drawn on both his research and artistic backgrounds to develop a class called “The Science of Art” that included studies and discussions on topics that involved dating, understanding and reverse engineering a variety of historical artifacts ranging from pioneer newspapers to ancient art.

“Mixing science and art together is just fun,” he says. “It’s a great way to make learning science more accessible.”

And the work has broader impacts as well. Relatively little is known about the mummy portraits, including whether the same artist painted multiple portraits. Analyzing pigments on an atomic level might provide the chemical fingerprint needed to link portraits to each other.

“Our results suggest one tool for documenting similarities regarding time and place of production of mummy portraits since most were grave-robbed and lack archaeological context,” Gates says.

“So we might be able to connect families,” Butt adds. “We might be able to connect artists to one another.”

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Zebra finches amazing at unmasking the bird behind the song

If songbirds could appear on “The Masked Singer” reality TV competition, zebra finches would likely steal the show. That’s because they can rapidly memorize the signature sounds of at least 50 different members of their flock, according to new research from the University of California, Berkeley.

In findings recently published in the journal Science Advances, these boisterous, red-beaked songbirds, known as zebra finches, have been shown to pick one another out of a crowd (or flock) based on a particular peer’s distinct song or contact call.

Like humans who can instantly tell which friend or relative is calling by the timbre of the person’s voice, zebra finches have a near-human capacity for language mapping. Moreover, they can remember each other’s unique vocalizations for months and perhaps longer, the findings suggest.

“The amazing auditory memory of zebra finches shows that birds’ brains are highly adapted for sophisticated social communication,” said study lead author Frederic Theunissen, a UC Berkeley professor of psychology, integrative biology and neuroscience.

Theunissen and fellow researchers sought to gauge the scope and magnitude of zebra finches’ ability to identify their feathered peers based purely on their unique sounds. As a result, they found that the birds, which mate for life, performed even better than anticipated.

“For animals, the ability to recognize the source and meaning of a cohort member’s call requires complex mapping skills, and this is something zebra finches have clearly mastered,” Theunissen said.

A pioneer in the study of bird and human auditory communication for at least two decades, Theunissen acquired a fascination and admiration for the communication skills of zebra finches through his collaboration with UC Berkeley postdoctoral fellow Julie Elie, a neuroethologist who has studied zebra finches in the forests of their native Australia. Their teamwork yielded groundbreaking findings about the communication skills of zebra finches.

Zebra finches usually travel around in colonies of 50 to 100 birds, flying apart and then coming back together. Their songs are typically mating calls, while their distance or contact calls are used to identify where they are, or to locate one another.

“They have what we call a ‘fusion fission’ society, where they split up and then come back together,” Theunissen said. “They don’t want to separate from the flock, and so, if one of them gets lost, they might call out ‘Hey, Ted, we’re right here.’ Or, if one of them is sitting in a nest while the other is foraging, one might call out to ask if it’s safe to return to the nest.”

These days, Theunissen keeps a few dozen zebra finches in aviaries on and around campus, 20 of which were used in this latest experiment.

In a two-part experiment, 20 captive zebra finches were trained to distinguish between different birds and their vocalizations. At first, half the birds were tested on memorizing songs, while the other half were assessed on distance or contact calls. They then switched those tasks.

Next, the zebra finches were placed, one at a time, inside a chamber and listened to sounds as part of a reward system. The goal was to train them to respond to particular zebra finches by hearing several different renditions of those birds’ distinct vocalizations and memorizing them.

By pecking a key inside the chamber, the bird subjects triggered an audio recording of a zebra finch vocalization. If they waited until the six-second recording ended, and it was part of the reward group, they received birdseed. If they pecked before the recording was finished, they moved to the next recording. Over several trials, they learned which vocalizations would yield birdseed, and which ones to skip.

Next, the zebra finches were introduced to more audio recordings from new zebra finches, to teach them to distinguish which vocalizations belonged to which bird. They soon learned to differentiate between 16 different zebra finches.

In fact, the zebra finches, both male and female, performed so well in the tests that four of them were given the more challenging task of distinguishing between 56 different zebra finches. On average, they succeeded in recognizing 42 different zebra finches, based on their signature sounds. Plus, they were still able to identify the birds based on their unique sounds a month later.

“I am really impressed by the spectacular memory abilities that zebra finches possess in order to interpret communication calls,” Theunissen said. “Previous research shows that songbirds are capable of using simple syntax to generate complex meanings and that, in many bird species, a song is learned by imitation. It is now clear that the songbird brain is wired for vocal communication.”

In addition to Theunissen, co-authors of the study are Kevin Yu and Willam Wood at UC Berkeley.

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