Everyone’s Saying The Same Thing About Ryan Gosling’s Oscar Nomination

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If you’ve seen Barbie (and judging by its blockbuster popularity, you probably have), you’ll know that Ryan Gosling played Stereotypical Ken in the film.

His character, whose official job was “beach” and whose main hobby was “pining after Margot Robbie’s Barbie,” delighted audiences with his hilarious antics and, er, fascinating singing voice.

Ryan Gosling has been nominated for the 2024 Oscars awards for Best Supporting Actor as Ken. The song played by his character, I’m Just Ken, which is ― well ― all about Ken has been nominated for Best Original Song.

And while nobody’s doubting the actor’s hilarious performance (which was undeniably incredible, and definitely Oscar-worthy in our opinion), some on X (formerly Twitter) have noticed that Greta Gerwig, the film’s director, and Margot Robbie ― Barbie’s main lead and producer of the film ― have not received a Best Director or Best Actress nomination.

This, some point out, is ironic given the feminist message of the film.

Of course, America Ferrera did receive an equivalent nomination for her role as Gloria in the movie (she’s been nominated for Best Supporting Actress). Greta Gerwig’s screenplay, co-written with Noah Baumbach, did get nominated for Best Adapted Screenplay.

And Margot Robbie is indirectly nominated for Best Picture via her production work.

Still, people on X thought the Best Actress and Best Director omissions were… interesting. Here are some responses:

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Alarming 30-fold rise in measles in Europe – WHO

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Urgent measures are needed now to stop further spread, the World Health Organization says.

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Theresa May horrified by type 1 diabetes disordered eating

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Better awareness and more NHS support are needed, the former prime minister says.

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New sustainable method for creating organic semiconductors

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Researchers at Linköping University, Sweden, have developed a new, more environmentally friendly way to create conductive inks for use in organic electronics such as solar cells, artificial neurons, and soft sensors. The findings, published in the journal Nature Communications, pave the way for future sustainable technology.

Organic electronics are on the rise as a complement and, in some cases, a replacement to traditional silicon-based electronics. Thanks to simple manufacturing, high flexibility, and low weight combined with the electrical properties typically associated with traditional semiconductors, it can be useful for applications such as digital displays, energy storage, solar cells, sensors, and soft implants.

Organic electronics are built from semiconducting plastics, known as conjugated polymers. However, processing conjugated polymers often requires environmentally hazardous, toxic, and flammable solvents. This is a major obstacle to the wide commercial and sustainable use of organic electronics.

Now, researchers at Linköping University have developed a new sustainable method for processing these polymers from water. In addition to being more sustainable, the new inks are also highly conductive.

“Our research introduces a new approach to processing conjugated polymers using benign solvents such as water. With this method, called ground-state electron transfer, we not only get around the problem of using hazardous chemicals, but we can also demonstrate improvements in material properties and device performance,” says Simone Fabiano, senior associate professor at the Laboratory of Organic Electronics.

When researchers tested the new conductive ink as a transport layer in organic solar cells, they found that both stability and efficiency were higher than with traditional materials. They also tested the ink to create electrochemical transistors and artificial neurons, demonstrating operating frequencies similar to biological neurons.

“I believe that these results can have a transformative impact on the field of organic electronics. By enabling the processing of organic semiconductors from green and sustainable solvents like water, we can mass-produce electronic devices with minimal impact on the environment,” says Simone Fabiano, a Wallenberg Academy Fellow.

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Good and bad news for people with low back pain

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Low back pain is a major cause of disability around the globe, with more than 570 million people affected. In the United States alone, health care spending on low back pain was $134.5 billion between 1996 and 2016, and costs are increasing.

“The good news is that most episodes of back pain recover, and this is the case even if you have already had back pain for a couple of months,” University of South Australia Professor Lorimer Moseley says.

“The bad news is that once you have had back pain for more than a few months, the chance of recovery is much lower. This reminds us that although nearly everyone experiences back pain, some people do better than others, but we don’t completely understand why.”

The systematic review and meta-analysis, conducted by an international team of researchers, included 95 studies with the goal of understanding the clinical course of acute (< 6 weeks), subacute (6 to less than 12 weeks) and persistent (12 to less than 52 weeks) low back pain.

For people with new back pain, pain and mobility problems lessened significantly in the first 6 weeks, but then recovery slowed.

This study filled a gap in a 2012 paper from the same research team, with new findings showing that many people with persistent low back pain (more than 12 weeks) continue to have moderate-to-high levels of pain and disability.

“These findings make it clear that back pain can persist even when the initial injury has healed,” Prof Moseley says.

“In these situations, back pain is associated with pain system hypersensitivity, not ongoing back injury. This means that if you have chronic back pain — back pain on most days for more than a few months — then it’s time to take a new approach to getting better.”

He notes that there are new treatments based on training both the brain and body that “focus on first understanding that chronic back pain is not a simple problem, which is why it does not have a simple solution, and then on slowly reducing pain system sensitivity while increasing your function and participation in meaningful activities.”

The authors state that identifying slowed recovery in people with subacute low back pain is important so that care can be escalated and the likelihood of persistent pain reduced.

Further research into treatments is needed to help address this common and debilitating condition, and to better understand it in people younger than 18 and older than 60 years.

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New reagent improves the process of making sulfur-containing compounds that may be used in medicines

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During the past decade, there has been significant development of new sulfur containing compounds that are used in various industries, including pharmaceuticals and agricultural products. Sulfoximines, sulfonimidoyl fluorides and sulfonimidamides are types of sulfur-containing chemical compounds that have wide-ranging potential as therapeutic drugs. However, the synthesis process for these compounds is complex and has several limitations. In a new article published in Nature Chemistry, Moffitt Cancer Center researchers describe their development of a new reagent that allows a more efficient approach to make sulfoximines, sulfonimidoyl fluorides and sulfonimidamides that may be used in medicines.

There are four main chemical approaches that are commonly used to create sulfoximines, sulfonimidoyl fluorides and sulfonimidamides. Recently an additional approach called sulfur fluorine exchange (SuFEx) chemistry has gained attention. But the approach has several limitations to its widespread use, such as the requirement for the use of high pressures.

The Moffitt research team wanted to develop a more efficient process to create sulfoximines, sulfonimidoyl fluorides and sulfonimidamides. Through a variety of chemical experiments and processes, they developed a reagent called t-BuSF that serves as a hub in the SuFEx chemical process to synthesize these sulfur-containing compounds. The use of t-BuSF decreased the number of steps required to make these compounds and improved the reaction times and stability of their chemical precursors. The researchers further demonstrated the potential utility of t-BuSF in medicinal chemistry in over 70 examples and by preparing five therapeutical targets and intermediates. They showed that t-BuSF was able to create these products in high yields with fewer synthesis steps.

“Given the cost-effectiveness and the chemical space accessible from this reagent platform, it is expected to have positive impacts on the discovery sciences from the development of new medicines and agrochemicals to the discovery of new ligands, organocatalysts and materials,” said Justin Lopchuk, Ph.D., associate member of the Department of Drug Discovery at Moffitt.

This study was supported by the National Institutes of Health (R35-GM142577, P30-CA076292) and the University of South Florida’s Chemical Purification, Analysis, and Screening Core Facility.

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Kayleigh McEnany Counsels Ex-Boss Trump On His Path To Victory Over Biden

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Fox News’ Kayleigh McEnany said on Sunday that Donald Trump must adopt a more appeasing tone and choose a fitting running mate to beat President Joe Biden. (Watch the video below.)

McEnany, who’s been accused of telling many lies on Trump’s behalf when she was the former president’s press secretary, praised remarks he made in New Hampshire earlier in the day, saying they were delivered with a “conciliatory tone”.

After GOP rival Ron DeSantis quit the race, the criminally indicted Trump praised the Florida governor’s campaign and said he appreciated his endorsement (as lukewarm as DeSantis’ words may have seemed). He also said he would retire his “Ron DeSanctimonious” nickname.

“That was a conciliatory tone,” McEnany said of Trump’s comments on The Big Weekend Show, which she co-hosts. “That reminds me of his victory speech in Iowa where he praised his opponents, praised his rivals. That’s the kind of tone he will need for the next nine months if he wants to prevail against Joe Biden.”

McEnany suggested Trump’s base will vote for him no matter what, so he has to muster support from other sources ― and that includes voters for his remaining GOP adversary, Nikki Haley.

“I think he [Trump] gets the DeSantis voter both in the primary and the general,” McEnany said. “The DeSantis voter tends to be a traditional conservative person of faith, and that naturally translates to Donald Trump. Where I think his challenge is both here and going forward into a general election, is winning over the Nikki Haley voter, winning over the establishment voter, winning over the independent, which is why I think that vice presidential pick is so important.”

“You must pick someone who helps to bring in that bloc because I believe the conservatives, the base, is going to come home, show up, rain or shine,” she continued. “You need the independent, you need the suburban women. You need that tone.”

A new CNN poll conducted before DeSantis’ departure showed Trump with an 11-point lead over Haley in New Hampshire’s primary on Tuesday. DeSantis pulled in just 6% of the vote.

Trump has said he already decided on a running mate but on Saturday he suggested his choice wasn’t so ironclad. He told Fox News that his selection has a “25% chance” of being the person he actually taps as his potential vice president.

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