“There is a tremendous amount of interest in what enables wildfire ignitions and what can be done to prevent them,” said Erica Fleishman, an Oregon State University professor. “This database increases the ability to access relevant information and contribute to wildfire preparedness and prevention.”

The Fire Program Analysis Fire-Occurrence Database was developed in 2013 by the U.S. Forest Service and since been updated five times. It incorporates basic information such as ignition location, discovery date and final wildfire size.

The revised database now includes many new environmental and social factors, such as topography and vegetation, social vulnerability and economic justice metrics, and practical attributes such as the distance from the ignition to the nearest road.

In addition to aiding on-the-ground firefighters and managers, the database could also help power companies evaluate short-term risk when deciding whether to implement a public safety power shutoff or land management agencies determine whether to reduce access to public lands or restrict campfires during certain times of year, Fleishman said.

“There seem to be a lot of policies that are guided to some extent by intuition or emotions rather than by a large body of evidence,” she said. “These data present one way to increase the objective evidence to consider when making those decisions.”

The team, including Fleishman, and led by Yavar Pourmohamad, a doctoral student at Boise State University, and Mojtaba Sadegh, an associate professor at Boise State, added nearly 270 additional attributes. The database now includes information on 2.3 million fires in the United States from 1992 to 2020.

“This provides a considerably deeper understanding of the individual and compounded impact of these attributes on wildfire ignitions and size,” Pourmohamad said. “It also identifies the unequal effects of wildfires on distinct human populations and ecosystems, which can, in turn, inform efforts to reduce inequities.”

Information from the database can also be incorporated into artificial intelligence and machine learning models that explain drivers of past fires or project likelihoods or effects of future fires, said Fleishman, who is affiliated with OSU’s College of Earth, Ocean, and Atmospheric Sciences and also directs the Oregon Climate Change Research Institute.

“It’s amazing what you can infer when you have the computational capacity and this much information,” she said. “You can ask a lot of questions that inform different actions in different places and to understand what is associated with wildfire ignitions and fire effects.”

A paper outlining the database was recently published in the journal Earth System Science Data.

Other co-authors of the paper are Eric Henderson and Sawyer Ball of Boise State; John Abatzoglou, University of California, Merced; Erin Belval, Karen Short, Matthew Reeves and Julia Olszewski, USDA Forest Service Rocky Mountain Research Station; Nicholas Nauslar, National Weather Service Storm Prediction Center; Philip Higuera, University of Montana; Amir AghaKouchak, University of California, Irvine; and Jeffrey Prestemon, USDA Forest Service Southern Research Station.

The research was supported by the Joint Fire Science Program, a program of the U.S. Forest Service and U.S. Department of the Interior.

Last year, the world emitted more than 37 billion metric tons of carbon dioxide, setting a new record high. As a result, sucking CO₂ out of the atmosphere has become an increasingly popular idea. Governments worldwide are banking on this technology, called direct air capture, to help them achieve climate goals and avoid the worst consequences of climate change.

But despite more than a dozen direct air capture facilities being up and running around the globe already, the technology still faces major technological hurdles — including its own high energy use.

In a study published May 1 in the journal ACS Energy Letters, researchers at the University of Colorado Boulder and collaborators revealed that a popular approach many engineers are exploring to reduce those energy costs would, in reality, fail. The team, including scientists at the National Renewable Energy Laboratory in Golden, Colorado and Delft University of Technology in the Netherlands, also proposed an alternative, more sustainable design for capturing CO₂ and converting it to fuels.

“Ideally, we want to take CO₂ out of the air and keep it out of the air,” said first author Hussain Almajed, a Ph.D. student in the Department of Chemical and Biological Engineering. “However, some of this CO₂ can be recycled into useful carbon-containing products, which is why researchers have proposed different ideas of how we can achieve that. Some of these ideas look very simple and elegant on paper, but researchers rarely check whether they are practical and economical in industrial settings.”

Trapping the gas

One of the most common direct air capture approaches is to use air contactors, essentially huge fans that pull air into a chamber filled with a basic liquid. CO₂ is acidic, so it naturally binds to and reacts with the solution to form harmless carbonate (the main ingredient in concrete) or bicarbonate (the ingredient in baking soda).

Stratos, one of the world’s largest direct air capture facilities under construction in Texas, uses this approach.

Once CO₂ is trapped in the carbonate or bicarbonate solutions, engineers must separate it out from the liquid so the liquid can return to the chamber to capture more CO₂.

Meanwhile, the captured carbon can be converted into things like plastics, carbonated drinks and even — with further processing — fuel to power homes and potentially airplanes.

But there is a catch. To release the trapped CO₂, companies need to heat the carbonate and bicarbonate solution to at least 900?C (1,652° F), a temperature solar and wind energy is unable to achieve. This step is usually powered by burning fossil-based fuels like natural gas or pure methane.

“If we have to release CO₂ in order to capture CO₂, it defeats the whole purpose of carbon capture,” said Wilson Smith, a professor in the Department of Chemical and Biological Engineering and a fellow of the Renewable and Sustainable Energy Institute at CU Boulder.

Close the loop

Researchers are actively looking for answers. One idea, commonly known as reactive capture, is to apply electricity to the carbonate and bicarbonate solutions, zapping the CO₂ and basic liquid apart in the chamber. In theory, the recycled liquid can then capture more CO₂, forming a closed-loop system.

“Reactive capture is now the buzzword in the field, and researchers proposed that it could help save energy and costs associated with carbon capture. But no one really assessed whether that’s realistic under industrial conditions,” Almajed said.

To do that, the team calculated the mass and energy outputs of the reactive capture units, based on given inputs, to understand how well the overall system would perform. They found that in an industrial setting, electricity would not be able to regenerate the basic liquid to re-capture more CO₂ from the air.

In fact, after five cycles of carbon capture and regeneration, the basic liquid could barely pull any CO₂ out of the air.

The team also suggested a tweak to the reactive capture process by adding a step called electrodialysis. The process splits additional water into acidic and basic ions, helping to maintain the basic liquid’s ability to absorb more CO₂. Electrodialysis can run on renewable electricity, making it a potentially sustainable way to turn captured CO₂ into useful products.

More importantly, electrodialysis can release CO₂ gas, which engineers can use to strengthen concrete.

“To me, turning CO₂ into rocks has to be one of the leading solutions to keep it out of the air over long periods of time,” Smith said. Concrete production is energy-intensive and responsible for 8% of global carbon emissions.

“This is solving multiple problems with one technology,” he said.

The root of the problem

According to the Intergovernmental Panel on Climate Change (IPCC), a team of scientists convened by the United Nations, carbon dioxide removal “is required to achieve global and national targets of net zero CO₂ and greenhouse gas emissions.”

Across the world, more than 20 direct air capture plants are in operation with 130 more currently under construction.

But Smith stresses that while carbon capture may have its place, cutting emissions is still the most critical step needed to avoid the worst outcomes of climate change.

“Imagining Earth as a bathtub, with the running water from the faucet being CO₂. The bathtub is getting full and becoming unlivable. Now, we have two options. We can use a little cup to scoop out the water, cup by cup, or we can turn the faucet off,” Smith said.

“Cutting emissions has to be the priority.”

When it comes to muscles and muscle disorders, the importance of a discovery like this cannot be overstated.

The muscle of muscles

The very core function of life — breathing — is controlled by your skeletal muscles, as is regulation of whole-body metabolism and every movement you make:

• And even blinking

In context

Skeletal muscles are formed during embryonic development by the fusion of hundreds of specialized cells called myoblasts. Adult skeletal muscles maintain regenerative capacity, which is attributed to the presence of muscle stem cells, named satellite cells.

After injury, satellite cells undergo several rounds of proliferation followed by their differentiation into myoblasts. These myoblasts once again fuse with each other and to injured myofibers to accomplish muscle regeneration.

In many muscular disorders, this intrinsic capacity of muscles to regenerate is diminished resulting in the loss of muscle mass and function.

The science

UH researchers found that Inositol-requiring enzyme 1, a key signaling protein, is essential for myoblast fusion during muscle formation and growth.

“During muscle regeneration, IRE1 augments the activity of X-box binding protein 1 which in turn stimulates the gene expression of multiple transmembrane proteins required for myoblast fusion,” reports Ashok Kumar, Else and Philip Hargrove Endowed Professor of pharmacy in the Department of Pharmacological and Pharmaceutical Sciences at the UH College of Pharmacy, in EMBO Reports.

According to researchers, increasing the levels of IRE1 or XBP1 in muscle stem cells outside the body, followed by their injection in patients’ muscle tissues will improve muscle repair and reduce the severity of disease.

“We also found that augmenting the levels of IRE1α or XBP1 in myoblasts leads to the formation of myotubes (muscle cells) having an increased diameter,” said Kumar.

That increase in diameter can be significant.

“Size is very important for muscle. Muscle grows only in size, not in number,” said Aniket Joshi, a graduate student in Kumar’s lab and first author on the article. “Muscular people have larger muscle cells. Larger muscles generally work better- can lift more weight, run and walk faster, and improve overall metabolism of the body and prevent various diseases, such as type II diabetes.”

Flexing their muscles

This new research is not the first flex for Kumar’s team. In 2021, research from Kumar’s lab published in the ELife journal described the role of the IRE1α/XBP1 signaling axis in regeneration of healthy skeletal muscle after acute injury and in models of Duchenne Muscular Dystrophy. In this study, they found that IRE1α/XBP1 signaling axis also plays an important cell autonomous role in satellite cells.

Along with Kumar and Joshi, post-doctoral fellow Meiricris Tomaz da Silva and research assistant professor, Anirban Roy conducted the research in Kumar’s lab. Other authors on the article from the University of Houston include Micah Castillo, Preethi Gunaratne, Mingfu Wu, Yu Liu, and a former post-doctoral fellow in Kumar’s lab Tatiana E. Koike along with Takao Iwawaki of Kanazawa Medical University, Japan.