Did we all believe a myth about depression?

A study some claim debunks antidepressants has gone viral. Was it read wrong?

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This Scottish Athlete’s Commonwealth Win Has Us Tearing Up For The Best Reason

It’s time to forget about the bleak news cycle for a moment and celebrate this athlete’s incredible race.

Not only did Scottish runner Eilish McColgan win the 10,000m at the Commonwealth Games on Wednesday night with a home crowd and make a new record championship time of 30:48:60, her success has sparked a great sense of nostalgia.

Eilish, 31, just won exactly the same Commonwealth Championship race her mum, Liz Nuttall, won 32 years ago, proving it really does run in the family.

Eilish (left) and her mother Liz McColgan winning their respective races
Eilish (left) and her mother Liz McColgan winning their respective races

The athlete, who has struggled with injuries in the past, was not in the lead until the final lap around the track when she suddenly overtook Kenyan rival Irine Cheptai in the home straight.

Unsurprisingly, Eilish sprinted over to her mum in the crowds when she realised she had won the race, and they shared a tender moment.

The following morning, Eilish told BBC Breakfast: “It was just an incredible experience, being in that stadium…the noise over the last 200m honestly just dragged me to that finish line.

“It was just an incredible evening and even more special to have my mum in the crowd, my dad, my partner Michael – it feels surreal to have won that so many years after my mum. I can’t put it into words.”

She said her mum simply told her “you’ve done it” when they had a celebratory hug at the end of the race.

Eilish also said she was “really nervous” before she hit the track, but that she couldn’t believe it when she not only won, but made a record time.

“I’ve actually only seen it once because a journalist sort of forced me to watch it when I was little, but it was never something that… I grew up with my mum allowing me to make my own decisions, my mum never pushed me into athletics and I never saw her medals.

“I was never forced to watch her races or anything like that, I made my own decision to come into this sport and I think that’s why I love it so much, I’m very passionate about it.”

“I don’t think it’s quite sunk in that I’ve literally replicated exactly what she’s done. It’s just very surreal right now.”

Eilish’s mother Liz also told BBC Radio’s Good Morning Scotland of her immense pride for her daughter, whom she still coaches.

Liz won two 10,000m Commonwealth gold medals in 1986 in Edinburgh and again in 1990 Auckland. She also became a world champion in 1991 and an Olympic silver medal in 1988.

She said: “As an athlete myself, you have fond memories of having success and whatever but when it’s your own children it’s like 100 times better.

’It’s just one of those really special moments and I was just thankful I was actually in the stadium and able to experience how the home support helped lift her to that gold medal.”

She also claimed that without the Birmingham crowd, “the last 150m would never have happened” for her daughter.

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Ofgem Has Changed Its Energy Cap Policy Again. Here’s Why It Matters

Energy regulator Ofgem has confirmed a major policy change today which could impact your bills, yet again.

Now the price cap will be updated quarterly (every three months) instead of every six months, in a bid to prevent large-scale disruption.

The cap was set out in law in 2018, and reflects the maximum suppliers can charge consumers per unit of energy.

It means suppliers can only take 1.9% as profit, but it’s not a cap on the maximum bill a household can be charged, as this is based on their usage.

While it may seem like an insignificant change in policy, it will have a substantial impact on your bills. Here’s what you need to know.

How important is the price cap?

Ofgem made headlines when it raised the price cap in April, meaning every household had to pay more for their annual energy bills.

The average household had to then start paying £700 more for their yearly annual bills, raising them to a record £1,971 (it was previously £1,227).

For many, this is seen as the start of the cost of living crisis.

While the cap stops prices rising and falling dramatically for consumers as wholesale prices go up, it does mean the cost of living is likely to only get harder in the short-term.

However, when wholesale prices fall, the reductions will be passed on the customers as Ofgem should lower the price cap. This will happen more quickly with the quarterly price cap.

The cap was set to rise again come October (to a staggering £3,358 a year according to analysts Cornwall Insight) but this policy change from Ofgem means the next price cap level will be published at the end of August.

Why has this changed?

Ofgem say this change prevents the cost of both gas and electricity lagging behind changes in the market, but admits the market is currently “volatile” so the price cap methodology is to be kept under review.

Ofgem CEO Jonathan Brearley acknowledged that “this situation is deeply worrying for many people”.

He then blamed Moscow’s decision to squeeze its gas supply to mainland Europe, which has a knock-on effect for the UK.

“As a result of Russia’s actions, the volatility in the energy markets we experienced last winter has lasted much longer, with much higher prices than ever before,” he said.

“And that means the cost of supplying electricity and gas to homes has increased considerably.

“The trade-offs we need to make on behalf of consumers are extremely difficult and there are simply no easy answers right now.”

He said this change means consumers will pay the “real cost of the energy”, but added: “We will keep working closely with the government, consumer groups and with energy companies on what further support can be provided to help with these higher prices.”

Why has the change been heavily criticised?

Back in May, MoneySavingExpert Martin Lewis laid into Ofgem’s early proposals to review the price cap every three months, rather than every six.

Explaining how he had lashed out at the regulator over the suggestions in a Twitter thread, he said the changes were “a fucking disgrace that sells consumers down the river”.

He apologised for his outburst, explaining: “I should’ve behaved better. My ire’s institutional not individual, it was inappropriate.”

However, Lewis claimed the changes would bring “dire consequences for consumers”.

Cornwall Insight also predicts that the energy price cap will go up to £3,615 in January. For comparison, it was £1,400 a year in October 2021.

MPs already called on the government at the end of July to take urgent action to help households amid warnings that prices will soar this autumn.

“Once again, the energy crisis is racing ahead of the government,” said Darren Jones, the chair of the business, energy and industrial strategy committee.

“To prevent millions from dropping into unmanageable debt it’s imperative that the support package is updated and implemented before October, when the squeeze will become a full-on throttling of household finances and further tip the economy towards recession.”

With this new policy change confirmed and the new price cap looming at the end of August, this threat of “unmanageable debt” is likely to only creep closer.

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Sandi Toksvig Pens Powerful Letter To Archbishop Of Canterbury After ‘Horrible’ Gay Sex Comments

Sandi Toksvig has penned an open letter to the Archbishop of Canterbury, after he “affirmed the validity” of a past declaration that gay sex is a sin.

The former Great British Bake Off host wrote that the Archbishop had “made a horrible mistake” by saying a past statement that marriage is “between a man and a woman”, and that same-sex relationships are “incompatible with scripture”, was “not in doubt”.

“I know we’ve never met and I should probably call you ‘your grace’ or ‘your eminence’ or something, but I wish we were friends,” Sandi began.

“If we were, I’d call you and say, ‘Justin, Justin, what are you doing?’. We’d have had a chat and maybe I could persuade you that you have made a horrible mistake. It’s what friends do for each other.”

The QI star continued: “You and your other religion pals got together at the Lambeth Conference and the main takeaway seems to be that gay sex is a sin. It was a sin in 1998 and you just wanted to make clear in 2022 that no one in your finely frocked gang has moved on from that.

“Seriously, with the state the world is in, that is what you wanted to focus on? You didn’t have other more pressing matters like, I don’t know, war or poverty?”

Justin Welby, the Archbishop of Canterbury
Justin Welby, the Archbishop of Canterbury

Anadolu Agency via Getty Images

Sandi went on to share statistics which revealed that young LGBTQ+ people are more likely to contemplate suicide and self-harm.

“Do you know why?” she questioned. “For many it’s because they don’t feel loved and love, Justin, is supposed to be at the core of what you do.”

She added: “The lives of LGBTQ+ people are at stake here. I have had credible death threats over the years sometimes requiring the very kind assistance of the police hate crime squad. Each and every one of those threats has come from an evangelical Christian.

“Inevitably, they have wanted to kill me on God’s behalf because although he may be omnipotent apparently he’s also very busy. Why just raising this matter is probably a bad idea for my health. I’ll cope, but what about my brothers and sisters who won’t?”

Sandi ended the letter by stating: “Call me, Justin. Let’s have coffee. Let me talk you round. You never know, I might even forgive you.”

The Danish comedian, presenter and activist came out as gay in 1994. She entered a civil partnership with her wife Debbie Toksvig in 2007.

Sandi and Debbie later renewed their vows on the day same-sex marriage was made legal in England in 2014.

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Chrissy Teigen and John Legend announce pregnancy

The US model says she and John Legend are expecting a baby, nearly two years after a stillbirth.

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Afra Rafeeq: India teen who died but raised millions to save her brother

Afra Rafeeq, who died this week, had raised millions of rupees to help get a crucial drug for her baby brother.

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Highest coral cover in central, northern Reef in 36 years

The northern and central Great Barrier Reef have recorded their highest amount of coral cover since the Australian Institute of Marine Science (AIMS) began monitoring 36 years ago.

Published today, AIMS’ Annual Summary Report on Coral Reef Condition for 2021/22 shows another year of increased coral cover across much of the Reef.

In the 87 representative reefs surveyed between August 2021 and May 2022 under the AIMS Long-Term Monitoring Program (LTMP), average hard coral cover in the region north of Cooktown increased to 36% (from 27% in 2021) and to 33% in the central Great Barrier Reef (from 26% in 2021).

However, average coral cover in the southern region (from Proserpine to Gladstone) decreased from 38% in 2021 to 34%.

AIMS CEO Dr Paul Hardisty said the results in the north and central regions were a sign the Reef could still recover, but the loss of coral cover in the southern region showed how dynamic the Reef was.

“A third of the gain in coral cover we recorded in the south in 2020/21 was lost last year due to ongoing crown-of-thorns starfish outbreaks,” he said.

“This shows how vulnerable the Reef is to the continued acute and severe disturbances that are occurring more often and are longer-lasting.”

Dr Hardisty said the increased frequency of mass coral bleaching events was “uncharted territory” for the Reef, with this year’s bleaching event the fourth in seven years and the first to occur during a La Niña.

“In our 36 years of monitoring the condition of the Great Barrier Reef we have not seen bleaching events so close together,” he said.

“Every summer the Reef is at risk of temperature stress, bleaching and potentially mortality and our understanding of how the ecosystem responds to that is still developing.

“The 2020 and 2022 bleaching events, while extensive, didn’t reach the intensity of the 2016 and 2017 events and, as a result, we have seen less mortality. These latest results demonstrate the Reef can still recover in periods free of intense disturbances.”

AIMS monitoring program team leader Dr Mike Emslie said the 2022 results built on the increases in coral cover reported for 2021, with most of the increase continuing to be driven by fast-growing Acropora corals.

“These corals are particularly vulnerable to wave damage, like that generated by strong winds and tropical cyclones,” he said.

“They are also highly susceptible to coral bleaching, when water temperatures reach elevated levels, and are the preferred prey for crown-of-thorns starfish. This means that large increases in hard coral cover can quickly be negated by disturbances on reefs where Acropora corals predominate.”

Dr Emslie said climate change was driving increasingly frequent and longer-lasting marine heatwaves.

“The peak of the most recent bleaching event in March occurred when the accumulated heat stress caused widespread bleaching but not extensive mortality,” he said.

“The increasing frequency of warming ocean temperatures and the extent of mass bleaching events highlights the critical threat climate change poses to all reefs, particularly while crown-of-thorns starfish outbreaks and tropical cyclones are also occurring. Future disturbance can reverse the observed recovery in a short amount of time.”

Background

The 36-year-long dataset of AIMS’ Long-Term Monitoring Program (LTMP) is the largest, longest, and most comprehensive information source on the health of the Great Barrier Reef. It helps determine long-term trends in the condition of coral communities across the Reef.

Percent hard coral cover describes the proportion of the reef that is covered in living hard coral. In 2021-22, most reefs surveyed had between 10 and 50 percent.

Bleaching is a coral’s response to stressful conditions such as heat. During bleaching, the coral animal loses its symbiotic algae and pigments, causing it to turn white and potentially die. Corals can survive a bleaching event, but they are under more stress.

Report; https://www.aims.gov.au/monitoring-great-barrier-reef/gbr-condition-summary-2021-22

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New patent-pending method mass-produces antitumor cells to treat blood diseases and cancer

A Purdue University chemical engineer has improved upon traditional methods to produce off-the-shelf human immune cells that show strong antitumor activity, according to a paper published in the peer-reviewed journal Cell Reports.

Xiaoping Bao, a Purdue University assistant professor from the Davidson School of Chemical Engineering, said CAR-neutrophils, or chimeric antigen receptor neutrophils, and engraftable HSCs, or hematopoietic stem cells, are effective types of therapies for blood diseases and cancer. Neutrophils are the most abundant white cell blood type and effectively cross physiological barriers to infiltrate solid tumors. HSCs are specific progenitor cells that will replenish all blood lineages, including neutrophils, throughout life.

“These cells are not readily available for broad clinical or research use because of the difficulty to expand ex vivo to a sufficient number required for infusion after isolation from donors,” Bao said. “Primary neutrophils especially are resistant to genetic modification and have a short half-life.”

Bao has developed a patent-pending method to mass-produce CAR-neutrophils from human pluripotent stem cells (hPSCs), that is, cells that self-renew and are able to become any type of human cell. The chimeric antigen receptor constructs were engineered to express on the surface of the hPSCs, which were directed into functional CAR-neutrophils through a novel, chemically defined protocol.

The method was created in collaboration with Qing Deng at Purdue’s Department of Biological Sciences, Hal E. Broxmeyer, now deceased, at Indiana University School of Medicine, and Xiaojun Lian at the Pennsylvania State University.

“We developed a robust protocol for massive production of de novo neutrophils from human pluripotent stem cells,” Bao said. “These hPSC-derived neutrophils displayed superior and specific antitumor activities against glioblastoma after engineering with chimeric antigen receptors.”

Bao disclosed the innovation to the Purdue Research Foundation Office of Technology Commercialization, which has applied for an international patent under the Patent Cooperation Treaty system of the World Intellectual Property Organization. The innovation has been optioned to an Indiana-headquartered life sciences company.

“We will also work with Dr. Timothy Bentley, professor of neurology and neurosurgery,and his team at the Purdue College of Veterinary Medicine to run clinical trials in pet dogs with spontaneous glioma,” Bao said.

This research project was partially supported by the Davidson School of Chemical Engineering and College of Engineering Startup Funds, Purdue Center for Cancer Research, Showalter Research Trust and federal grants from the National Science Foundation and National Institute of General Medical Sciences.

Story Source:

Materials provided by Purdue University. Original written by Steve Martin. Note: Content may be edited for style and length.

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As reflective satellites fill the skies, students are making sure astronomers can adapt

As satellites crawl across the sky, they reflect light from the sun back down to Earth, especially during the first few hours after sunset and the first few hours before sunrise. As more companies launch networks of satellites into low-Earth orbit, a clear view of the night sky is becoming rarer. Astronomers, in particular, are trying to find ways to adapt.

With that in mind, a team of University of Arizona students and faculty completed a comprehensive study to track and characterize the brightness of satellites, using a ground-based sensor they developed to measure satellites’ brightness, speed and paths through the sky. Their work could be helpful for astronomers, who, if notified of incoming bright satellites, could close the shutters of their telescope-mounted cameras to prevent light trails from tainting their long-exposure astronomical images.

The research team was led by professor of planetary sciences Vishnu Reddy, who also co-leads — with professor of systems and industrial engineering Roberto Furfaro — the university’s Space Domain Awareness lab, which tracks and characterizes all kinds of objects orbiting Earth and the moon.

Grace Halferty, a senior graduating this summer with a bachelor’s degree in aerospace and mechanical engineering, is the lead author of the study, which is published in Monthly Notices of the Royal Astronomical Society. The study details how the team created a satellite tracking device to measure the brightness and position of SpaceX Starlink satellites and compared those observations to government satellite tracking data from the Space Track Catalog database.

“Until now, most photometric — or brightness — observations that were available were done by naked eye,” Halferty said. “This is one of the first comprehensive photometric studies out there to go through peer review. The satellites are challenging to track with traditional astronomical telescopes, because they are so bright and fast-moving, so we built what’s basically a small sensor with a camera lens ourselves because there was nothing off the shelf available.”

The team made 353 measurements of 61 satellites over two years and found that the position of Starlink satellites as recorded in the government’s Space Track Catalog only differed by an average of 0.3 arc seconds from the UArizona calculations. An arc second on the sky is about the size of a dime held 2.5 miles away. The tiny difference is probably due to natural lag times in the government data, Reddy said. Because that data is based on estimated orbits calculated days earlier, rather than on real-time observations, positioning errors can build up.

“This suggests that there is hope that astronomers can use these data to close the shutter of their telescopes in time amid the growing chaos in the skies above,” Reddy said.

A stellar traffic jam

Starlink is a large network of satellites, also called a mega constellation, operated by SpaceX with the goal of providing global internet coverage. SpaceX started launching Starlink satellites in 2019. Today, more than 2,700 Starlink satellites have launched — a fraction of the intended total of 42,000 satellites.

Other examples of satellite constellations include 31 GPS satellites and 75 iridium satellites for communication. Other entities have plans to launch more satellites into low and medium Earth orbit in the next few years. Amazon, for example, plans to launch 3,000 satellites, and the Chinese government plans to launch 13,000. These satellites will orbit no higher than 22,000 miles above Earth.

The problem with satellites is that they require power harvested from solar panels, which can reflect sunlight at ground-based telescopes and, in turn, impact astronomical observations from telescopes around the world. About 30% of all telescope images will be impacted by at least one satellite trail once the Starlink constellation is complete, said research team member Tanner Campbell, a graduate research assistant in the Department of Aerospace and Mechanical Engineering.

“As other constellations are added, the problem will only get worse for ground-based astronomical surveys,” he said.

These satellites are even more reflective right after launch, while they are still relatively low and tightly clustered before they spread throughout their orbit over time. They are often as bright as Saturn or Jupiter, two of the brightest objects in the night sky. As they maneuver into higher orbits, they become slightly fainter.

A moving target

SpaceX has deployed a few different methods to darken its Starlink satellites. For example, VisorSat satellites rely on a shade to block additional sunlight, making them 1.6 times fainter. DarkSat satellites, on the other hand, rely on an anti-reflective coating that makes them 4.8 times fainter. However, DarkSats got too hot, so SpaceX moved away from that specific method. Since August 2021, all Starlink satellites are VisorSats.

“While these modifications are steps in the right direction, they also don’t dim the satellites enough for astronomical surveys,” said research team member Adam Battle, a graduate student studying planetary science.

In July, SpaceX announced new strategies. One involves mirrors that reflect sunlight away from Earth and another involves using darker building materials. Reddy’s team plans to study how effective these methods are at reducing sunlight reflection back to Earth.

While knowing exactly where satellites are is helpful to astronomers, the act of shutting the cameras adds overhead costs for telescope operations. Surveys become less efficient when astronomers have to close the shutter or throw away contaminated images. For example, a survey that would take five years to complete could take 10% to 20% more time if survey efficiency is down. Costs will continue to increase as more satellites are launched, Reddy said.

The team plans to build upon its success by studying the brightness of the latest generation of Starlink satellites in four different colored filters — the same ones used in astronomical surveys of the sky to tease out different information from stars, planets and more. To achieve this, the team has worked with Tucson-based small business Starizona to build a sensor that can take pictures of satellites in four colors simultaneously.

“Working with local small businesses is a win for us as it provides our students an opportunity to rapidly prototype and bring a new system online,” Reddy said.

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Junior doctors’ pay offer concerns hospital leaders

The morale of junior doctors will be damaged by a lower pay rise than other staff, hospitals in England say.

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